WO2009016488A3 - Compositions comprising tetracyclic antidepressants for treatment of cancer and related methods - Google Patents

Compositions comprising tetracyclic antidepressants for treatment of cancer and related methods Download PDF

Info

Publication number
WO2009016488A3
WO2009016488A3 PCT/IB2008/002006 IB2008002006W WO2009016488A3 WO 2009016488 A3 WO2009016488 A3 WO 2009016488A3 IB 2008002006 W IB2008002006 W IB 2008002006W WO 2009016488 A3 WO2009016488 A3 WO 2009016488A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
compositions
treatment
related methods
tetracyclic antidepressants
Prior art date
Application number
PCT/IB2008/002006
Other languages
French (fr)
Other versions
WO2009016488A2 (en
Inventor
Anat Oren
Alex Diber
Sergey Nemzer
Yaron Kinar
Gad S. Cojocaru
Yossi Cohen
Original Assignee
Compugen, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen, Ltd. filed Critical Compugen, Ltd.
Publication of WO2009016488A2 publication Critical patent/WO2009016488A2/en
Publication of WO2009016488A3 publication Critical patent/WO2009016488A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method for treating cancer, for example breast cancer, urologic cancer, glioma, and/or hormone-refractory prostate cancer, and/or a related disorder in a patient comprises administering HTR2A antagonists to the patient.
PCT/IB2008/002006 2007-08-02 2008-07-30 Compositions comprising tetracyclic antidepressants for treatment of cancer and related methods WO2009016488A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93525207P 2007-08-02 2007-08-02
US93524907P 2007-08-02 2007-08-02
US60/935,252 2007-08-02
US60/935,249 2007-08-02

Publications (2)

Publication Number Publication Date
WO2009016488A2 WO2009016488A2 (en) 2009-02-05
WO2009016488A3 true WO2009016488A3 (en) 2009-12-30

Family

ID=40304978

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/002006 WO2009016488A2 (en) 2007-08-02 2008-07-30 Compositions comprising tetracyclic antidepressants for treatment of cancer and related methods

Country Status (1)

Country Link
WO (1) WO2009016488A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201908587PA (en) * 2012-08-06 2019-10-30 S1 Pharmaceuticals Inc Treatment regimens
US20140271727A1 (en) * 2013-03-18 2014-09-18 National Yang-Ming University Method of using an antidepressant for increasing immunity of a subject and treating cancer
US11185542B2 (en) 2016-07-28 2021-11-30 Jiangsu Yahong Meditech Co., Ltd. Uses of dopamine beta-hydroxylase (DBH) inhibitors and serotonin receptor (5-HT) antagonists for the treatment of cancer
EP3348266A1 (en) 2017-01-16 2018-07-18 Leukos Biotech, S.L. Combination therapy for treating cancer
US20230263798A1 (en) * 2020-09-01 2023-08-24 The General Hospital Corporation Compositions and methods for treating therapy resistant cancer
WO2023006954A1 (en) * 2021-07-30 2023-02-02 Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) Asenapine for use in cancer
CN113694205B (en) * 2021-09-23 2023-05-16 山东第一医科大学(山东省医学科学院) Application of 5-HT receptor inhibitor and cisplatin in preparation of medicines for treating liver cancer
CN114159440A (en) * 2021-11-05 2022-03-11 复旦大学附属肿瘤医院 Application of flibanserin and derivatives thereof in preparation of antitumor drugs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072824A1 (en) * 2001-06-01 2004-04-15 Adam Telerman Methods and compositions for the treatment of cancer
US20050267027A1 (en) * 2004-04-05 2005-12-01 Lounsbury Karen M Use of erythropoietin for treatment of cancer
US20070041981A1 (en) * 2005-06-01 2007-02-22 Northwestern University Compositions and methods for altering immune function

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072824A1 (en) * 2001-06-01 2004-04-15 Adam Telerman Methods and compositions for the treatment of cancer
US20050267027A1 (en) * 2004-04-05 2005-12-01 Lounsbury Karen M Use of erythropoietin for treatment of cancer
US20070041981A1 (en) * 2005-06-01 2007-02-22 Northwestern University Compositions and methods for altering immune function

Also Published As

Publication number Publication date
WO2009016488A2 (en) 2009-02-05

Similar Documents

Publication Publication Date Title
WO2009016488A3 (en) Compositions comprising tetracyclic antidepressants for treatment of cancer and related methods
PH12016502066A1 (en) Methods of treating bladder cancer
TW200738262A (en) Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
WO2008122049A3 (en) Methods and compositions for reduction of side effects of therapeutic treatments
NZ587706A (en) Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
GB0700560D0 (en) Device and method for the treatment of diseased tissue such as tumours
WO2008137867A3 (en) Compositions comprising mir34 therapeutic agents for treating cancer
TN2010000208A1 (en) Treatment of breast cancer with a parp inhibitor alone or in combination with anti-tumor agents
MX2010009670A (en) Polymer paclitaxel conjugates and methods for treating cancer.
UA104426C2 (en) Anti-tumoural effects of cannabinoid combinations
MY162903A (en) Methods of treatment of pancreatic cancer
WO2007100675A3 (en) Collagenase for treating cellulite
MX343135B (en) Fumagillol type compounds and methods of making and using same.
MX2010000465A (en) Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders.
WO2008130704A3 (en) PDGFRβ-SPECIFIC INHIBITORS
IL197633A (en) Combination of mva and taxane for the treatment of her-2 over expressing cancer
WO2010014595A3 (en) Methods and compositions for delivering therapeutic agents in the treatment of b-cell related disorders
BRPI0908635A8 (en) compound, pharmaceutical composition and cancer treatment method
WO2007146335A3 (en) Compounds and compositions for treatment of cancer
IN2012DN02423A (en)
WO2010065329A3 (en) Nanoparticles for cancer treatment
MX2009012421A (en) Inhibition of tumor metastasis by anti neuropilin 2 antibodies.
WO2007134203A3 (en) Anticancer treatments with a combination of docetaxel and ecteinascidin
TN2013000333A1 (en) Combinations comprising macitentan for the treatment of glioblastoma multiforme
WO2011044523A3 (en) Compositions and methods for treating obesity

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08788971

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 08788971

Country of ref document: EP

Kind code of ref document: A2