MX2021007604A - Biomarcadores de desregulacion de neutrofilos como diagnostico de gingivitis. - Google Patents

Biomarcadores de desregulacion de neutrofilos como diagnostico de gingivitis.

Info

Publication number
MX2021007604A
MX2021007604A MX2021007604A MX2021007604A MX2021007604A MX 2021007604 A MX2021007604 A MX 2021007604A MX 2021007604 A MX2021007604 A MX 2021007604A MX 2021007604 A MX2021007604 A MX 2021007604A MX 2021007604 A MX2021007604 A MX 2021007604A
Authority
MX
Mexico
Prior art keywords
gingivitis
mif
methods
deregulation
neutrophil
Prior art date
Application number
MX2021007604A
Other languages
English (en)
Inventor
Ying Yang
Harsh Mahendra Trivedi
Camille Zenobia
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Publication of MX2021007604A publication Critical patent/MX2021007604A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56955—Bacteria involved in periodontal diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G01N2333/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4 or KC
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G01N2333/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1or LDCF-2

Abstract

Métodos para determinar una o más relaciones de quimiocinas en el líquido crevicular gingival de un individuo seleccionado del grupo que consiste en: Se describen MIF:MIP1a, MIF:CXCL1; MIF:CXCL5; MIF:CXCL8; MIF:CXCL2; y MIF:CXCL6 y métodos para identificar a un individuo que tiene gingivitis que comprende determinar una o más relaciones de las quimiocinas en el líquido crevicular gingival. Se describen métodos para tratar individuos que se identifica que tienen gingivitis mediante la determinación de una o más relaciones de las quimiocinas en el líquido crevicular gingival. También se describen métodos para monitorear a los individuos de tratamiento que tienen gingivitis.
MX2021007604A 2018-12-26 2019-12-17 Biomarcadores de desregulacion de neutrofilos como diagnostico de gingivitis. MX2021007604A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862785167P 2018-12-26 2018-12-26
PCT/US2019/066813 WO2020139620A1 (en) 2018-12-26 2019-12-17 Biomarkers of neutrophil deregulation as diagnostic for gingivitis

Publications (1)

Publication Number Publication Date
MX2021007604A true MX2021007604A (es) 2021-08-11

Family

ID=69182639

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021007604A MX2021007604A (es) 2018-12-26 2019-12-17 Biomarcadores de desregulacion de neutrofilos como diagnostico de gingivitis.

Country Status (8)

Country Link
US (1) US11573228B2 (es)
EP (1) EP3884277A1 (es)
CN (1) CN113383235A (es)
AU (1) AU2019417313B2 (es)
BR (1) BR112021011897A2 (es)
CA (1) CA3123290A1 (es)
MX (1) MX2021007604A (es)
WO (1) WO2020139620A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022173884A1 (en) * 2021-02-10 2022-08-18 Colgate-Palmolive Company Biomarker of gingivitis diagnosis and treatment
KR102561554B1 (ko) * 2021-04-14 2023-07-28 부산대학교 산학협력단 치주질환 진단용 바이오마커 조성물, 치주질환 치료 효용성 평가용 바이오마커 조성물 및 이를 이용한 진단키트

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI98961C (fi) * 1994-08-26 1997-09-10 Medix Biochemica Ab Oy Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi
CN102046199A (zh) * 2008-03-20 2011-05-04 卡罗勒斯治疗公司 使用抗mif抗体的治疗方法
US8367350B2 (en) * 2009-04-29 2013-02-05 Morehouse School Of Medicine Compositions and methods for diagnosis, prognosis and management of malaria
CA2773978A1 (en) * 2009-09-23 2011-03-31 Carolus Therapeutics, Inc. Methods of treating inflammation
WO2014037811A2 (en) * 2012-09-07 2014-03-13 The Governors Of The University Of Alberta Methods and compositions for diagnosis of inflammatory liver disease
CA2884089A1 (en) * 2012-09-10 2014-03-13 Koninklijke Philips N.V. Analysis of saliva proteome for biomarkers of gingivitis and periodontitis using ft-icr-ms/ms
BR112015017403A2 (pt) * 2013-01-21 2017-11-21 Abbvie Inc biomarcadores de terapia de combinação de anti-tnf e anti-il17 para doença inflamatória
WO2015187169A1 (en) * 2014-06-05 2015-12-10 Colgate-Palmolive Company Assay for oral inflammation
US9964472B2 (en) 2016-06-29 2018-05-08 The Procter & Gamble Company Methods for sampling gingival metabolites
JP2018072163A (ja) * 2016-10-28 2018-05-10 山本　徳則 間質性膀胱炎鑑別用マーカー及びその用途
CA3003529A1 (en) * 2017-05-04 2018-11-04 John Christian Haught Methods of reduction for measuring oral lavage proteins

Also Published As

Publication number Publication date
CN113383235A (zh) 2021-09-10
AU2019417313A1 (en) 2021-06-24
EP3884277A1 (en) 2021-09-29
BR112021011897A2 (pt) 2021-08-31
WO2020139620A1 (en) 2020-07-02
US20220146512A1 (en) 2022-05-12
AU2019417313B2 (en) 2023-01-19
US11573228B2 (en) 2023-02-07
CA3123290A1 (en) 2020-07-02

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