MX2012003514A - Metodos para tratamiento de inflamaciones. - Google Patents
Metodos para tratamiento de inflamaciones.Info
- Publication number
- MX2012003514A MX2012003514A MX2012003514A MX2012003514A MX2012003514A MX 2012003514 A MX2012003514 A MX 2012003514A MX 2012003514 A MX2012003514 A MX 2012003514A MX 2012003514 A MX2012003514 A MX 2012003514A MX 2012003514 A MX2012003514 A MX 2012003514A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- mif
- treating inflammation
- cxcr2
- cxcr4
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 102100028989 C-X-C chemokine receptor type 2 Human genes 0.000 abstract 2
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 abstract 2
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 abstract 2
- 108010018951 Interleukin-8B Receptors Proteins 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se divulgan aquí, en algunas realizaciones, métodos para tratar un trastorno mediado por MIF. En algunas realizaciones, el método comprende administrar un agente que inhibe (i) el enlazamiento de MIF a CXCR2 y CXCR4 y/o (ii) la activación por MIF de CXCR2 y CXCR4; (iii) la capacidad del MIF para formar un homomultímero; o una combinación de los mismos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24521409P | 2009-09-23 | 2009-09-23 | |
US31903910P | 2010-03-30 | 2010-03-30 | |
PCT/US2010/050047 WO2011038149A2 (en) | 2009-09-23 | 2010-09-23 | Methods of treating inflammation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012003514A true MX2012003514A (es) | 2012-04-19 |
Family
ID=43796491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012003514A MX2012003514A (es) | 2009-09-23 | 2010-09-23 | Metodos para tratamiento de inflamaciones. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2480579A4 (es) |
KR (1) | KR20120105429A (es) |
CN (1) | CN102725311A (es) |
AU (1) | AU2010298249A1 (es) |
BR (1) | BR112012006468A2 (es) |
CA (1) | CA2773978A1 (es) |
IN (1) | IN2012DN02423A (es) |
MX (1) | MX2012003514A (es) |
WO (1) | WO2011038149A2 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013010955A1 (en) | 2011-07-15 | 2013-01-24 | Morphosys Ag | Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt) |
US9328174B2 (en) * | 2012-05-09 | 2016-05-03 | Novartis Ag | Chemokine receptor binding polypeptides |
AU2013262397B2 (en) * | 2012-05-17 | 2017-07-27 | Anji Pharmaceuticals Inc. | Methods and uses for proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors |
TW201605886A (zh) * | 2013-11-14 | 2016-02-16 | 巴克斯特保健公司 | 作爲治療標靶的mif |
CA3017345A1 (en) | 2016-03-11 | 2017-09-14 | Ardea Biosciences, Inc. | Cxcr-2 inhibitors for treating crystal arthropathy disorders |
AU2019282132A1 (en) | 2018-06-05 | 2020-12-17 | Anji Pharmaceuticals Inc. | Compositions and methods for treating pancreatitis |
US11573228B2 (en) * | 2018-12-26 | 2023-02-07 | Colgate-Palmolive Company | Biomarkers of neutrophil deregulation as diagnostic for gingivitis |
JP2023517616A (ja) * | 2020-03-11 | 2023-04-26 | バイオラインアールエックス・リミテッド | 急性呼吸窮迫症候群およびウイルス感染の治療用のcxcr4阻害剤 |
WO2021219495A1 (en) * | 2020-04-28 | 2021-11-04 | Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch | Methods for treating or preventing a viral infection or inhibiting viral replication |
CN112656934A (zh) * | 2021-01-22 | 2021-04-16 | 深圳市图微安创科技开发有限公司 | 多肽at03在治疗原发性胆汁性胆管炎药物中的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7534605B2 (en) * | 1999-06-08 | 2009-05-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases |
WO2003072753A2 (en) * | 2002-02-27 | 2003-09-04 | Emory University | Multimeric binding complexes |
CN102174108B (zh) * | 2002-03-01 | 2016-06-29 | 免疫医疗公司 | 内在化抗-cd74抗体和使用方法 |
US7897349B2 (en) * | 2003-12-30 | 2011-03-01 | The United States Of America As Represented By The Department Of Veterans Affairs | Macrophage migration inhibitory factor (MIF) as marker for urological inflammatory disease |
US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
BRPI0910259A2 (pt) * | 2008-03-20 | 2015-12-01 | Carolus Therapeutics Inc | métodos de tratamento de inflamação |
WO2010056910A2 (en) * | 2008-11-12 | 2010-05-20 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
-
2010
- 2010-09-23 AU AU2010298249A patent/AU2010298249A1/en not_active Abandoned
- 2010-09-23 WO PCT/US2010/050047 patent/WO2011038149A2/en active Application Filing
- 2010-09-23 EP EP10819481.2A patent/EP2480579A4/en not_active Withdrawn
- 2010-09-23 IN IN2423DEN2012 patent/IN2012DN02423A/en unknown
- 2010-09-23 CA CA2773978A patent/CA2773978A1/en not_active Abandoned
- 2010-09-23 MX MX2012003514A patent/MX2012003514A/es unknown
- 2010-09-23 KR KR1020127010455A patent/KR20120105429A/ko not_active Application Discontinuation
- 2010-09-23 CN CN2010800526286A patent/CN102725311A/zh active Pending
- 2010-09-23 BR BR112012006468A patent/BR112012006468A2/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP2480579A2 (en) | 2012-08-01 |
CA2773978A1 (en) | 2011-03-31 |
IN2012DN02423A (es) | 2015-08-21 |
EP2480579A4 (en) | 2013-07-31 |
KR20120105429A (ko) | 2012-09-25 |
WO2011038149A2 (en) | 2011-03-31 |
CN102725311A (zh) | 2012-10-10 |
WO2011038149A3 (en) | 2011-10-27 |
BR112012006468A2 (pt) | 2016-08-09 |
AU2010298249A1 (en) | 2012-04-19 |
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