IN2012DN01954A - - Google Patents

Download PDF

Info

Publication number
IN2012DN01954A
IN2012DN01954A IN1954DEN2012A IN2012DN01954A IN 2012DN01954 A IN2012DN01954 A IN 2012DN01954A IN 1954DEN2012 A IN1954DEN2012 A IN 1954DEN2012A IN 2012DN01954 A IN2012DN01954 A IN 2012DN01954A
Authority
IN
India
Prior art keywords
partially processed
amount
bont
unprocessed
solution
Prior art date
Application number
Other languages
English (en)
Inventor
Harold V Taylor
Karl-Heinz Eisele
Cornelia Brunn
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41466928&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN01954(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of IN2012DN01954A publication Critical patent/IN2012DN01954A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1282Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96402Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
    • G01N2333/96405Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
    • G01N2333/96408Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
    • G01N2333/96419Metalloendopeptidases (3.4.24)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
IN1954DEN2012 2009-10-21 2010-10-18 IN2012DN01954A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27945309P 2009-10-21 2009-10-21
EP09173612 2009-10-21
PCT/EP2010/065618 WO2011048044A1 (en) 2009-10-21 2010-10-18 System for determining unprocessed and partially processed neurotoxin type a

Publications (1)

Publication Number Publication Date
IN2012DN01954A true IN2012DN01954A (ko) 2015-08-21

Family

ID=41466928

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1954DEN2012 IN2012DN01954A (ko) 2009-10-21 2010-10-18

Country Status (16)

Country Link
US (2) US8841080B2 (ko)
EP (1) EP2491384B1 (ko)
JP (1) JP5709877B2 (ko)
KR (1) KR101788340B1 (ko)
CN (1) CN102597769B (ko)
AU (1) AU2010309932B2 (ko)
BR (1) BR112012009436A2 (ko)
CA (1) CA2773478C (ko)
ES (1) ES2449303T3 (ko)
HK (1) HK1173493A1 (ko)
IL (1) IL218455A (ko)
IN (1) IN2012DN01954A (ko)
MX (1) MX2012004454A (ko)
PT (1) PT2491384E (ko)
RU (1) RU2545825C9 (ko)
WO (1) WO2011048044A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2578250C (en) * 2004-07-26 2013-03-05 Merz Pharma Gmbh & Co. Kgaa Therapeutic composition with a botulinum neurotoxin
RU2549463C1 (ru) * 2013-12-03 2015-04-27 Федеральное бюджетное учреждение науки Государственный научный центр прикладной микробиологии и биотехнологии (ФБУН ГНЦ ПМБ) Способ определения ботулинического нейротоксина типа а на основе иммунодетекции, сопряженной с полимеразной цепной реакцией

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2340299A (en) 1998-01-26 1999-08-09 University Of Massachusetts Biologically active hemagglutinin from type a (clostridium botulinum) and methods of use
US6667158B1 (en) 1998-12-17 2003-12-23 The United States Of America As Represented By The Secretary Of The Army Antibodies against type a botulinum neurotoxin
CA2371279A1 (en) 1999-05-12 2000-11-16 Leonard A. Smith Recombinant vaccine against botulinum neurotoxin
US20080171347A1 (en) * 2003-04-11 2008-07-17 Atassi M Zouhair Determining and reducing immunoresistance to botulinum toxin therapy using botulinum toxin a peptides
FR2869908B1 (fr) * 2004-05-05 2006-07-28 Pharmaleads Substrat peptidique reconnu par la toxine botulique de type a, bont/a et son utilisation pour detecter et/ou doser ladite toxine ou des inhibiteurs de son activite
CN100575363C (zh) * 2007-03-07 2009-12-30 中国人民解放军军事医学科学院微生物流行病研究所 人源抗a型肉毒神经毒素基因工程抗体及其制备方法与用途
US7732579B2 (en) * 2007-06-13 2010-06-08 The United States Of America As Represented By The Secretary Of Agriculture High-affinity monoclonal antibodies for botulinum toxin type A
US9447175B2 (en) * 2009-02-19 2016-09-20 Merz Pharma Gmbh & Co. Kgaa Means and methods for manufacturing highly pure neurotoxin
CN101503472B (zh) * 2009-03-17 2011-08-10 中国人民解放军军事医学科学院生物工程研究所 抗a型肉毒毒素的人源性中和抗体及其应用

Also Published As

Publication number Publication date
AU2010309932B2 (en) 2015-04-16
JP5709877B2 (ja) 2015-04-30
KR101788340B1 (ko) 2017-10-19
WO2011048044A1 (en) 2011-04-28
JP2013508701A (ja) 2013-03-07
RU2545825C2 (ru) 2015-04-10
MX2012004454A (es) 2012-05-22
BR112012009436A2 (pt) 2017-02-21
US9213026B2 (en) 2015-12-15
CN102597769B (zh) 2014-11-05
ES2449303T3 (es) 2014-03-19
CA2773478A1 (en) 2011-04-28
IL218455A (en) 2015-10-29
US20120214182A1 (en) 2012-08-23
US8841080B2 (en) 2014-09-23
PT2491384E (pt) 2014-02-21
AU2010309932A1 (en) 2012-04-05
EP2491384B1 (en) 2013-12-04
US20140349322A1 (en) 2014-11-27
RU2545825C9 (ru) 2015-06-20
KR20120102639A (ko) 2012-09-18
HK1173493A1 (en) 2013-05-16
EP2491384A1 (en) 2012-08-29
CA2773478C (en) 2018-07-17
RU2012120572A (ru) 2013-11-27
IL218455A0 (en) 2012-04-30
CN102597769A (zh) 2012-07-18

Similar Documents

Publication Publication Date Title
MX360513B (es) Medios y metodos para la determinacion de la actividad biologica de polipeptidos de neurotoxina en celulas.
UA95958C2 (en) Antibody that binds to cd22, immunoconjugates and uses therefor
MX2011011045A (es) Medios y metodos para determinacion de cantidad de polipeptido de neurotoxina y de sus actividades cataliticas y proteoliticas.
WO2008081849A1 (ja) ペプチドおよびタンパク質定量法
NZ609824A (en) Immunochromatography devices, methods and kits
WO2008134526A3 (en) Glycoprotein profiling of bladder cancer
WO2010091182A3 (en) Methods for screening candidate agents for modulating prorenin and renin, assays for detecting prorenin, and antibodies used therein
WO2012035296A3 (en) Assay for prions
EA200802169A1 (ru) Способы анализа гидроксикарбоната лантана
ATE438856T1 (de) Biomarker für eierstockkrebs: mit ctap3 verwandte proteine
GB201014028D0 (en) In-situ reagent
IN2012DN03911A (ko)
WO2010014854A3 (en) Antibodies that neutralize botulinum neurotoxins
MX2010005377A (es) Metodo para caracterizacion de proteina policlonal recombinante.
PL2185937T5 (pl) Sposób wykrywania posocznicy u ludzi
WO2010075360A3 (en) Methods for detection of sepsis
WO2008112258A3 (en) Modified proteases
MX2017011195A (es) Metodos para mejorar la captacion especifica de neurotoxinas botulinicas en las celulas.
EA201171178A1 (ru) Устройство и способ для определения и количественного анализа аналитов, в частности, микотоксинов
DK2118666T3 (da) Fremgangsmåde til normalisering af koncentrationen af analytter i en urinprøve
IN2012DN01954A (ko)
WO2012164525A3 (en) Aging biomarkers
WO2012145516A3 (en) Methods and kits for quantitative determination of total organic acid content in a coolant
WO2012077139A8 (en) Method for the diagnosis of a carcinoma and uses thereof
MX2009008525A (es) La determinacion cuantitativa de risedronato en orina mediante spe-lc-ms-ms.