IN2012DN01661A - - Google Patents

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Publication number
IN2012DN01661A
IN2012DN01661A IN1661DEN2012A IN2012DN01661A IN 2012DN01661 A IN2012DN01661 A IN 2012DN01661A IN 1661DEN2012 A IN1661DEN2012 A IN 1661DEN2012A IN 2012DN01661 A IN2012DN01661 A IN 2012DN01661A
Authority
IN
India
Prior art keywords
disclosed
compounds
intended
kits
abstract
Prior art date
Application number
Other languages
English (en)
Inventor
H Alex Brown
Craig W Lindsley
Alex G Waterson
Sarah A Scott
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Publication of IN2012DN01661A publication Critical patent/IN2012DN01661A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN1661DEN2012 2009-07-24 2010-07-23 IN2012DN01661A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22849209P 2009-07-24 2009-07-24
PCT/US2010/043045 WO2011011680A1 (en) 2009-07-24 2010-07-23 Isoform selective phospholipase d inhibitors

Publications (1)

Publication Number Publication Date
IN2012DN01661A true IN2012DN01661A (enExample) 2015-06-05

Family

ID=43499428

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1661DEN2012 IN2012DN01661A (enExample) 2009-07-24 2010-07-23

Country Status (14)

Country Link
US (1) US9127005B2 (enExample)
EP (1) EP2456307B1 (enExample)
JP (1) JP2013500260A (enExample)
KR (1) KR20120090034A (enExample)
CN (1) CN102573474A (enExample)
AU (1) AU2010275526A1 (enExample)
BR (1) BR112012001586A2 (enExample)
CA (1) CA2768940C (enExample)
IL (1) IL217720A0 (enExample)
IN (1) IN2012DN01661A (enExample)
MX (1) MX2012001064A (enExample)
RU (1) RU2012106657A (enExample)
SG (1) SG178102A1 (enExample)
WO (1) WO2011011680A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9453017B2 (en) 2011-09-30 2016-09-27 Vanderbilt University Antiviral therapies with phospholipase D inhibitors

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2012106657A (ru) 2009-07-24 2013-08-27 Вандербилт Юниверсити Изоформы избирательного ингибитора фосфолипазы d
US20140163055A1 (en) * 2012-12-11 2014-06-12 Vanderbilt University Methods and compositions of treating hiv infection
EP2931277A4 (en) * 2012-12-11 2016-07-27 Univ Vanderbilt PROCEDURE AND COMPOSITIONS WITH ACTIVE INHIBITORS AND / OR PHOSPHOLIPASE D INHIBITORS
CN114778844A (zh) * 2022-03-07 2022-07-22 天津市肿瘤医院(天津医科大学肿瘤医院) Pld1作为评估肿瘤患者对于化疗药物敏感性的分子标志物的用途
EP4541791A4 (en) * 2022-06-16 2026-06-24 Shionogi & Co Dihydrooxadiazinone compound and pharmaceutical use thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1281502B1 (it) 1995-06-13 1998-02-18 Sardinian Antiviral Research C Impiego di un inibitore non nucleosidico della trascrittasi inversa in associazione con inibitori nucleosidici per il trattamento della
US6187559B1 (en) 1997-08-28 2001-02-13 Novartis Ag Phospholipase D gene
AU6262601A (en) 2000-05-25 2001-12-03 Ben Williger Phospholipase d effectors for therapy and screening
US6482829B2 (en) * 2000-06-08 2002-11-19 Hoffmann-La Roche Inc. Substituted heterocyclic siprodecane compound active as an antagonist of neurokinin 1 receptor
US20060172363A1 (en) 2002-09-18 2006-08-03 Postech Foundation Peptide complexes containing phospholipase d
BRPI0517423A (pt) * 2004-12-27 2008-10-07 Astrazeneca Ab composto, composição farmacêutica, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com disfunção do glutamato em um animal, e, uso em um composto
AU2006233101B2 (en) 2005-02-23 2011-09-01 Arbiser, Jack Honokiol derivatives for the treatment of proliferative disorders
KR101077295B1 (ko) * 2006-05-18 2011-10-26 에프. 호프만-라 로슈 아게 아데노신 a2b 수용체 길항물질로서의 티아졸로-피라미딘/피리딘 우레아 유도체
US20100009970A1 (en) 2008-03-19 2010-01-14 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2010037081A1 (en) 2008-09-29 2010-04-01 Palatin Technologies, Inc. Melanocortin receptor-specific spiro-piperidine compounds
EP2413993B1 (en) 2009-03-31 2020-07-15 Sanofi-Aventis Deutschland GmbH Drug delivery device body
WO2010138869A1 (en) 2009-05-29 2010-12-02 The Trustees Of Columbia University In The City Of New York Modulation of phospholipase d for the treatment of neurodegenerative disorders
RU2012106657A (ru) 2009-07-24 2013-08-27 Вандербилт Юниверсити Изоформы избирательного ингибитора фосфолипазы d
US9149445B2 (en) 2009-07-27 2015-10-06 The Trustees Of Princeton University Inhibition of glycerol-3-phosphate acyltransferase (GPAT) and associated enzymes for treatment of viral infections
US9453017B2 (en) 2011-09-30 2016-09-27 Vanderbilt University Antiviral therapies with phospholipase D inhibitors
US20140163055A1 (en) 2012-12-11 2014-06-12 Vanderbilt University Methods and compositions of treating hiv infection
EP2931277A4 (en) 2012-12-11 2016-07-27 Univ Vanderbilt PROCEDURE AND COMPOSITIONS WITH ACTIVE INHIBITORS AND / OR PHOSPHOLIPASE D INHIBITORS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9453017B2 (en) 2011-09-30 2016-09-27 Vanderbilt University Antiviral therapies with phospholipase D inhibitors

Also Published As

Publication number Publication date
EP2456307A1 (en) 2012-05-30
US20120214832A1 (en) 2012-08-23
WO2011011680A1 (en) 2011-01-27
IL217720A0 (en) 2012-03-29
CN102573474A (zh) 2012-07-11
US9127005B2 (en) 2015-09-08
EP2456307B1 (en) 2016-11-02
CA2768940C (en) 2018-03-13
MX2012001064A (es) 2012-07-17
EP2456307A4 (en) 2013-01-16
SG178102A1 (en) 2012-03-29
JP2013500260A (ja) 2013-01-07
CA2768940A1 (en) 2011-01-27
BR112012001586A2 (pt) 2015-09-01
KR20120090034A (ko) 2012-08-16
RU2012106657A (ru) 2013-08-27
AU2010275526A1 (en) 2012-03-15

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