IN2012DN01322A - - Google Patents

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Publication number
IN2012DN01322A
IN2012DN01322A IN1322DEN2012A IN2012DN01322A IN 2012DN01322 A IN2012DN01322 A IN 2012DN01322A IN 1322DEN2012 A IN1322DEN2012 A IN 1322DEN2012A IN 2012DN01322 A IN2012DN01322 A IN 2012DN01322A
Authority
IN
India
Prior art keywords
antibody
cmet
prognosis
disorders associated
relates
Prior art date
Application number
Other languages
English (en)
Inventor
Liliane Goetsch
Alexandra Jouhanneaud
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of IN2012DN01322A publication Critical patent/IN2012DN01322A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IN1322DEN2012 2009-08-21 2010-08-23 IN2012DN01322A (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23586409P 2009-08-21 2009-08-21
EP09305777A EP2287197A1 (de) 2009-08-21 2009-08-21 Anti-cMET-Antikörper und seine Verwendung zur Erkennung und Diagnose von Krebs
US34800510P 2010-05-25 2010-05-25
PCT/EP2010/062271 WO2011020925A1 (en) 2009-08-21 2010-08-23 Anti-cmet antibody and its use for the detection and the diagnosis of cancer

Publications (1)

Publication Number Publication Date
IN2012DN01322A true IN2012DN01322A (de) 2015-06-05

Family

ID=41571045

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1322DEN2012 IN2012DN01322A (de) 2009-08-21 2010-08-23

Country Status (19)

Country Link
US (2) US8673302B2 (de)
EP (2) EP2287197A1 (de)
JP (1) JP5951486B2 (de)
KR (1) KR20120051734A (de)
CN (1) CN102639564B (de)
AR (1) AR077901A1 (de)
AU (1) AU2010284944B2 (de)
BR (1) BR112012003759A2 (de)
CA (1) CA2769427C (de)
ES (1) ES2692522T3 (de)
IL (1) IL218202A (de)
IN (1) IN2012DN01322A (de)
MX (1) MX2012002139A (de)
NZ (2) NZ598194A (de)
RU (1) RU2582265C2 (de)
SG (1) SG178339A1 (de)
TW (1) TW201111781A (de)
WO (1) WO2011020925A1 (de)
ZA (1) ZA201202076B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2287197A1 (de) * 2009-08-21 2011-02-23 Pierre Fabre Medicament Anti-cMET-Antikörper und seine Verwendung zur Erkennung und Diagnose von Krebs
SG187886A1 (en) 2010-08-31 2013-04-30 Genentech Inc Biomarkers and methods of treatment
KR101444837B1 (ko) 2011-06-03 2014-09-30 한국생명공학연구원 HGF 활성을 가지는 c-Met에 대한 인간항체 및 이의 용도
AU2012312515A1 (en) 2011-09-19 2014-03-13 Genentech, Inc. Combination treatments comprising c-met antagonists and B-raf antagonists
KR20130036993A (ko) * 2011-10-05 2013-04-15 삼성전자주식회사 c-Met의 SEMA 도메인 내의 에피토프에 특이적으로 결합하는 항체
CN104395752B (zh) * 2011-11-21 2017-09-15 泰纬生命科技股份有限公司 对hec1活性调节剂具有反应的癌症的生物标记
TW201326193A (zh) 2011-11-21 2013-07-01 Genentech Inc 抗-c-met抗體之純化
GB201121914D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Method for patient selection
US9260531B2 (en) 2012-05-09 2016-02-16 Eli Lilly And Company Anti-c-met antibodies
EP2863946A4 (de) * 2012-06-21 2016-04-13 Sorrento Therapeutics Inc Antigenbindende proteine zur bindung von par-2
CA2900097A1 (en) 2013-02-22 2014-08-28 F. Hoffmann-La Roche Ag Methods of treating cancer and preventing drug resistance
US10214593B2 (en) 2013-04-02 2019-02-26 Samsung Electronics Co., Ltd. Anti-idiotype antibody against anti-c-MET antibody
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
WO2015031614A1 (en) * 2013-08-28 2015-03-05 Abbvie Inc. Soluble cmet assay
WO2015031626A1 (en) * 2013-08-28 2015-03-05 Abbvie Inc. Soluble cmet assay
WO2015032695A1 (en) * 2013-09-09 2015-03-12 Ventana Medical Systems, Inc. Scoring method for mesothelin protein expression
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
JP2017516458A (ja) 2014-03-24 2017-06-22 ジェネンテック, インコーポレイテッド c−met拮抗剤による癌治療及びc−met拮抗剤のHGF発現との相関
WO2015179835A2 (en) 2014-05-23 2015-11-26 Genentech, Inc. Mit biomarkers and methods using the same
JP6864953B2 (ja) 2014-12-09 2021-04-28 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Axlに対するヒトモノクローナル抗体
EP3253791A1 (de) * 2015-02-03 2017-12-13 INSERM - Institut National de la Santé et de la Recherche Médicale Konformationelle anti-rho-gtpase-einzeldomänenantikörper und verwendungen davon
WO2016135041A1 (en) 2015-02-26 2016-09-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Fusion proteins and antibodies comprising thereof for promoting apoptosis
ES2795818T3 (es) * 2015-03-18 2020-11-24 Seattle Genetics Inc Anticuerpos CD48 y conjugados de los mismos
EP3411067B1 (de) 2016-02-05 2021-10-20 Helixmith Co., Ltd Anti-c-met-antikörper und verwendungen davon
EP4233909A3 (de) 2016-05-17 2023-09-20 AbbVie Biotherapeutics Inc. Anti-cmet-antikörper-wirkstoffkonjugate und verfahren zu deren verwendung
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法
RU2735918C2 (ru) * 2018-06-07 2020-11-10 Общество с ограниченной ответственностью "ДЖЕЙВИС ДИАГНОСТИКС" Набор реагентов для выявления маркера эпителиальных карцином
CN112351998B (zh) * 2018-06-29 2022-07-22 苏州智核生物医药科技有限公司 Pd-l1结合多肽及其用途
KR102396194B1 (ko) * 2018-12-07 2022-05-10 서울대학교 산학협력단 항 c-Met 아고니스트 항체 및 이의 용도
WO2020244654A1 (en) * 2019-06-06 2020-12-10 Apollomics Inc. (Hangzhou) Method for treating cancer patients using c-met inhibitor
MX2022002886A (es) 2019-09-16 2022-04-06 Regeneron Pharma Proteinas de union met radiomarcadas para la obtencion de imagenes por inmuno-pet.
US20240165253A1 (en) 2020-09-01 2024-05-23 Remegen Co., Ltd. Anti-c-met antibody-drug conjugate and applications thereof
IL300952A (en) * 2020-09-08 2023-04-01 Ideaya Biosciences Inc Drug combination and tumor treatment
WO2023240272A2 (en) * 2022-06-09 2023-12-14 Santa Ana Bio, Inc. Antibodies targeting c-kit and/or siglec and uses thereof
WO2024030341A1 (en) 2022-07-30 2024-02-08 Pinetree Therapeutics, Inc. Compositions for targeted lysosomal degradaton and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214344B1 (en) * 1995-06-02 2001-04-10 Genetech, Inc. Hepatocyte growth factor receptor antagonists and uses thereof
AU2002357388A1 (en) * 2001-12-27 2003-07-24 The United States Of America, As Represented By The Department Of Veterans Affairs Monoclonal antibody imaging and therapy of tumors that express met and bind hepatocyte growth factor
US20040208876A1 (en) * 2003-04-18 2004-10-21 Kim Kyung Jin Monoclonal antibodies to hepatocyte growth factor
US7964365B2 (en) * 2005-11-08 2011-06-21 The United States of Americam as represented by the Secretary, Department of Health and Human Services Methods for diagnosing and monitoring the progression of cancer
SG169382A1 (en) * 2006-02-06 2011-03-30 Metheresis Translational Res S A Ch Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products
EP2014681A1 (de) * 2007-07-12 2009-01-14 Pierre Fabre Medicament Neue Antikörper zur Hemmung der C-Met-Dimerisation und Verwendungen davon
US7892770B2 (en) * 2007-08-24 2011-02-22 Van Andel Research Institute Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods
AR074439A1 (es) * 2008-12-02 2011-01-19 Pf Medicament Anticuerpo anti-cmet (receptor c-met)
US8545839B2 (en) * 2008-12-02 2013-10-01 Pierre Fabre Medicament Anti-c-Met antibody
EP2287197A1 (de) * 2009-08-21 2011-02-23 Pierre Fabre Medicament Anti-cMET-Antikörper und seine Verwendung zur Erkennung und Diagnose von Krebs

Also Published As

Publication number Publication date
IL218202A0 (en) 2012-04-30
CA2769427A1 (en) 2011-02-24
EP2467402A1 (de) 2012-06-27
CA2769427C (en) 2020-03-10
ES2692522T3 (es) 2018-12-04
BR112012003759A2 (pt) 2017-07-11
EP2467402B1 (de) 2018-08-01
US20140295452A1 (en) 2014-10-02
SG178339A1 (en) 2012-03-29
MX2012002139A (es) 2012-03-07
NZ598194A (en) 2015-05-29
AU2010284944B2 (en) 2016-01-28
AU2010284944A1 (en) 2012-03-08
RU2582265C2 (ru) 2016-04-20
JP5951486B2 (ja) 2016-07-13
CN102639564A (zh) 2012-08-15
ZA201202076B (en) 2012-11-28
JP2013502213A (ja) 2013-01-24
IL218202A (en) 2017-07-31
TW201111781A (en) 2011-04-01
EP2287197A1 (de) 2011-02-23
CN102639564B (zh) 2015-01-07
WO2011020925A1 (en) 2011-02-24
AR077901A1 (es) 2011-09-28
US8673302B2 (en) 2014-03-18
KR20120051734A (ko) 2012-05-22
NZ700437A (en) 2016-04-29
US20120149031A1 (en) 2012-06-14
RU2012109004A (ru) 2013-09-27

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