IN2012DN00303A - - Google Patents
Info
- Publication number
- IN2012DN00303A IN2012DN00303A IN303DEN2012A IN2012DN00303A IN 2012DN00303 A IN2012DN00303 A IN 2012DN00303A IN 303DEN2012 A IN303DEN2012 A IN 303DEN2012A IN 2012DN00303 A IN2012DN00303 A IN 2012DN00303A
- Authority
- IN
- India
- Prior art keywords
- avß5
- integrin
- treating
- preventing
- sepsis
- Prior art date
Links
- 102000006495 integrins Human genes 0.000 abstract 3
- 108010044426 integrins Proteins 0.000 abstract 3
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22841609P | 2009-07-24 | 2009-07-24 | |
| PCT/US2010/043211 WO2011011775A1 (en) | 2009-07-24 | 2010-07-26 | Methods and compositions for treating and preventing disease associated with avb5 integrin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN00303A true IN2012DN00303A (cs) | 2015-05-08 |
Family
ID=43499449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN303DEN2012 IN2012DN00303A (cs) | 2009-07-24 | 2010-07-26 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10087252B2 (cs) |
| EP (1) | EP2456460A4 (cs) |
| JP (1) | JP5755647B2 (cs) |
| KR (1) | KR101752515B1 (cs) |
| CN (1) | CN102481347A (cs) |
| AU (1) | AU2010275367B2 (cs) |
| BR (1) | BR112012001463A2 (cs) |
| CA (1) | CA2767409C (cs) |
| IL (1) | IL217406A (cs) |
| IN (1) | IN2012DN00303A (cs) |
| WO (1) | WO2011011775A1 (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201215414D0 (en) * | 2012-08-30 | 2012-10-17 | Isis Innovation | Composition and use |
| WO2014151680A1 (en) * | 2013-03-15 | 2014-09-25 | Biogen Idec Ma Inc. | Treatment and prevention of acute kidney injury using anti-alpha v beta 5 antibodies |
| EP3191519A1 (en) * | 2014-09-12 | 2017-07-19 | Biogen MA Inc. | Humanized anti-alpha v beta 5 antibodies and uses thereof |
| JP2019524702A (ja) * | 2016-07-05 | 2019-09-05 | ザ ロックフェラー ユニバーシティー | テトラヒドロナフチルリジンペンタンアミドインテグリンアンタゴニスト |
| AU2020272766A1 (en) * | 2019-04-08 | 2021-11-18 | Biogen Ma Inc. | Anti-integrin antibodies and uses thereof |
Family Cites Families (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| US5506337A (en) | 1985-03-15 | 1996-04-09 | Antivirals Inc. | Morpholino-subunit combinatorial library and method |
| EP0247091B1 (en) | 1985-11-01 | 1993-09-29 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5010175A (en) | 1988-05-02 | 1991-04-23 | The Regents Of The University Of California | General method for producing and selecting peptides with specific properties |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| IE66205B1 (en) | 1990-06-14 | 1995-12-13 | Paul A Bartlett | Polypeptide analogs |
| US5650489A (en) | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| US5527679A (en) | 1991-05-01 | 1996-06-18 | Dana Farber Cancer Institute | β5 protein and DNA encoding the same |
| DE4123341A1 (de) | 1991-07-15 | 1993-01-21 | Thomae Gmbh Dr K | Phenylalkylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4142366A1 (de) | 1991-07-15 | 1993-06-24 | Thomae Gmbh Dr K | Phenylalkylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5777085A (en) | 1991-12-20 | 1998-07-07 | Protein Design Labs, Inc. | Humanized antibodies reactive with GPIIB/IIIA |
| US6291196B1 (en) | 1992-01-31 | 2001-09-18 | Research Corporation Technologies, Inc. | Melanoma and prostate cancer specific antibodies for immunodetection and immunotherapy |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US6210671B1 (en) | 1992-12-01 | 2001-04-03 | Protein Design Labs, Inc. | Humanized antibodies reactive with L-selectin |
| US5519134A (en) | 1994-01-11 | 1996-05-21 | Isis Pharmaceuticals, Inc. | Pyrrolidine-containing monomers and oligomers |
| US5593853A (en) | 1994-02-09 | 1997-01-14 | Martek Corporation | Generation and screening of synthetic drug libraries |
| US5539083A (en) | 1994-02-23 | 1996-07-23 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid combinatorial libraries and improved methods of synthesis |
| US5525735A (en) | 1994-06-22 | 1996-06-11 | Affymax Technologies Nv | Methods for synthesizing diverse collections of pyrrolidine compounds |
| US5549974A (en) | 1994-06-23 | 1996-08-27 | Affymax Technologies Nv | Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof |
| US5780426A (en) | 1995-06-07 | 1998-07-14 | Ixsys, Incorporated | Fivemer cyclic peptide inhibitors of diseases involving αv β3 |
| US5569588A (en) | 1995-08-09 | 1996-10-29 | The Regents Of The University Of California | Methods for drug screening |
| US7053041B1 (en) | 1996-05-31 | 2006-05-30 | The Scripps Research Institute | Methods and compositions useful for inhibition of αvβ5mediated angiogenesis |
| UA60311C2 (uk) | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| CO4920232A1 (es) | 1997-01-08 | 2000-05-29 | Smithkline Beecham Corp | Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin |
| TW589189B (en) | 1997-08-04 | 2004-06-01 | Scras | Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis |
| KR100586202B1 (ko) | 1997-08-08 | 2006-06-07 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | ανβ6 길항제로의 급성 폐 상해 및 섬유증의 치료방법 |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
| GB9827152D0 (en) | 1998-07-03 | 1999-02-03 | Devgen Nv | Characterisation of gene function using double stranded rna inhibition |
| DE19842415A1 (de) | 1998-09-16 | 2000-03-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
| DE69942671D1 (de) | 1998-12-01 | 2010-09-23 | Facet Biotech Corp | Humanisierte antikoerper gegen gamma-interferon |
| WO2000044914A1 (en) | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| WO2001023376A1 (en) | 1999-09-29 | 2001-04-05 | Ortho-Mcneil Pharmaceutical, Inc. | Isonipecotamides for the treatment of integrin-mediated disorders |
| AU1086501A (en) | 1999-10-15 | 2001-04-30 | Carnegie Institution Of Washington | Rna interference pathway genes as tools for targeted genetic interference |
| GB9927444D0 (en) | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
| WO2001053297A1 (en) | 2000-01-20 | 2001-07-26 | Merck & Co., Inc. | Alpha v integrin receptor antagonists |
| CA2397665A1 (en) | 2000-01-24 | 2001-07-26 | Merck & Co., Inc. | Alpha v integrin receptor antagonists |
| NZ520299A (en) | 2000-02-03 | 2004-05-28 | Eisai Co Ltd | Integrin expression inhibitors containing sulphonamide derivatives |
| US20020004042A1 (en) | 2000-04-18 | 2002-01-10 | Factor Phillip H. | Gene therapy for pulmonary edema using adenovirus vectors encoding a beta2adrenergic receptor gene |
| UY26780A1 (es) | 2000-06-15 | 2002-01-31 | Pharmacia Corp | Cicloalquil avb3 antagonistas |
| US7163681B2 (en) | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
| US7288390B2 (en) | 2000-08-07 | 2007-10-30 | Centocor, Inc. | Anti-dual integrin antibodies, compositions, methods and uses |
| DE10041423A1 (de) | 2000-08-23 | 2002-03-07 | Merck Patent Gmbh | Biphenylderivate |
| US20020072500A1 (en) | 2000-09-27 | 2002-06-13 | Thomas Rogers | Hydroxy acid integrin antagonists |
| ATE320258T1 (de) | 2000-10-24 | 2006-04-15 | Merck & Co Inc | Dibenzoxazepin-alpha-v-integrin- rezeptorantagonist |
| JP2004532616A (ja) | 2000-12-28 | 2004-10-28 | ジョンソン・アンド・ジョンソン・リサーチ・ピー・ティー・ワイ・リミテッド | 二本鎖rna仲介遺伝子抑制 |
| EP1393075A4 (en) | 2001-04-04 | 2006-06-14 | Allergan Inc | METHODS OF SCREENING AND USE OF ANGIOGENESIS INHIBITORS |
| WO2002081467A1 (en) | 2001-04-09 | 2002-10-17 | Ortho-Mcneil Pharmaceutical, Inc. | Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders |
| US20040019206A1 (en) | 2001-09-27 | 2004-01-29 | Peter Ruminiski | Lactone integrin antagonists |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| DE60335118D1 (de) | 2002-08-16 | 2011-01-05 | Janssen Pharmaceutica Nv | Piperidinylverbindungen, die selektiv an integrine binden |
| CN1964740A (zh) * | 2004-04-02 | 2007-05-16 | 加利福尼亚大学董事会 | 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 |
| KR20110102142A (ko) * | 2008-12-12 | 2011-09-16 | 유니버시티 오브 유타 리서치 파운데이션 | 혈관 장벽 기능을 촉진하고 폐 섬유증을 치료하기 위한 조성물 및 방법 |
| TWI552751B (zh) | 2011-06-20 | 2016-10-11 | H 朗德貝克公司 | 投予4-((1r,3s)-6-氯-3-苯基-二氫茚-1-基)-1,2,2-三甲基-哌及其鹽用於治療精神分裂症的方法 |
| WO2014151680A1 (en) * | 2013-03-15 | 2014-09-25 | Biogen Idec Ma Inc. | Treatment and prevention of acute kidney injury using anti-alpha v beta 5 antibodies |
| EP3191519A1 (en) * | 2014-09-12 | 2017-07-19 | Biogen MA Inc. | Humanized anti-alpha v beta 5 antibodies and uses thereof |
-
2010
- 2010-07-26 IN IN303DEN2012 patent/IN2012DN00303A/en unknown
- 2010-07-26 KR KR1020127003723A patent/KR101752515B1/ko not_active Expired - Fee Related
- 2010-07-26 US US13/386,323 patent/US10087252B2/en active Active
- 2010-07-26 EP EP10803008A patent/EP2456460A4/en not_active Withdrawn
- 2010-07-26 WO PCT/US2010/043211 patent/WO2011011775A1/en not_active Ceased
- 2010-07-26 BR BR112012001463A patent/BR112012001463A2/pt not_active Application Discontinuation
- 2010-07-26 AU AU2010275367A patent/AU2010275367B2/en not_active Ceased
- 2010-07-26 CN CN2010800333673A patent/CN102481347A/zh active Pending
- 2010-07-26 CA CA2767409A patent/CA2767409C/en not_active Expired - Fee Related
- 2010-07-26 JP JP2012521872A patent/JP5755647B2/ja not_active Expired - Fee Related
-
2012
- 2012-01-05 IL IL217406A patent/IL217406A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2456460A1 (en) | 2012-05-30 |
| IL217406A0 (en) | 2012-02-29 |
| WO2011011775A1 (en) | 2011-01-27 |
| KR101752515B1 (ko) | 2017-06-29 |
| KR20120052312A (ko) | 2012-05-23 |
| JP5755647B2 (ja) | 2015-07-29 |
| CA2767409A1 (en) | 2011-01-27 |
| JP2013500269A (ja) | 2013-01-07 |
| US20120328604A1 (en) | 2012-12-27 |
| US10087252B2 (en) | 2018-10-02 |
| CN102481347A (zh) | 2012-05-30 |
| AU2010275367B2 (en) | 2015-09-03 |
| CA2767409C (en) | 2018-10-30 |
| BR112012001463A2 (pt) | 2016-03-15 |
| IL217406A (en) | 2016-02-29 |
| EP2456460A4 (en) | 2013-02-20 |
| AU2010275367A1 (en) | 2012-02-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL273607A (en) | Humanized antibodies against liv-1, preparations containing them and their uses | |
| CY1122978T1 (el) | Αντισωματα εναντι-vla-4 | |
| TN2010000213A1 (en) | Wise binding antibodies and epitopes | |
| IL212099A0 (en) | Cross-species specific psmaxcd3 bispecific single chain antibodies, compositions comprising the same and uses thereof | |
| PH12013500810B1 (en) | Anti-il-23 antibodies | |
| MX2010005682A (es) | Anticuerpos bivalentes, biespecificos. | |
| MX2010005888A (es) | Anticuerpos bivalentes biespecificos. | |
| MX2010006396A (es) | Anticuerpos bivalentes, biespecificos. | |
| UA100874C2 (en) | Bivalent bispecific antibodies | |
| PH12014501108A1 (en) | Anti-il-36r antibodies | |
| IL216014A0 (en) | Antibodies immunorective with heregulin-her3 complexes, compositions comprising the same and uses thereof | |
| WO2013006490A3 (en) | Antibodies that specifically bind to tim3 | |
| WO2012019024A3 (en) | Her3-binding molecules and immunoconjugates thereof | |
| EA201291039A1 (ru) | Антитела, связывающие cd27 человека, и их применение | |
| MX2014008102A (es) | Inmunoglobulinas de dominio variable dual contra receptores. | |
| IL205127A (en) | Antibody to aβ is humanized, a preparation containing it and its uses | |
| BR112013007229A2 (pt) | ''composição,mistura e processo''. | |
| ZA201102081B (en) | Engineered anti0il-13 antibodies,compositions,methods and uses | |
| IN2012DN02046A (cs) | ||
| EA201390575A1 (ru) | Неантагонистические egfr-связывающие молекулы и их иммуноконъюгаты | |
| IL212066A (en) | 4cxcr antibodies, preparations containing them, processes for their production and selection and use for cancer treatment | |
| PL2354161T3 (pl) | Przeciwciało anty -NR10 i jego zastosowanie | |
| IL226023A0 (en) | Antibodies against 5dr, preparations containing them and their uses | |
| WO2011103490A3 (en) | INTEGRIN αVβ8 NEUTRALIZING ANTIBODY | |
| IL219827A0 (en) | Lyophilization methods, compositions, and kits |