IN2012DE00337A - - Google Patents
Info
- Publication number
- IN2012DE00337A IN2012DE00337A IN337DE2012A IN2012DE00337A IN 2012DE00337 A IN2012DE00337 A IN 2012DE00337A IN 337DE2012 A IN337DE2012 A IN 337DE2012A IN 2012DE00337 A IN2012DE00337 A IN 2012DE00337A
- Authority
- IN
- India
- Prior art keywords
- addition
- hydrolysis
- organic solvent
- solution
- required quantity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/377,047 US9872873B2 (en) | 2012-02-06 | 2012-03-29 | Process for preparing stable pharmaceutical compositions of compounds susceptible to hydrolysis |
PCT/IB2012/051513 WO2013117969A1 (en) | 2012-02-06 | 2012-03-29 | Process for preparing stable pharmaceutical compositions of compounds susceptible to hydrolysis |
EP12719066.8A EP2811984B1 (en) | 2012-02-06 | 2012-03-29 | Process for preparing stable pharmaceutical compositions of compounds susceptible to hydrolysis |
IN337DE2012 IN2012DE00337A (ru) | 2012-02-06 | 2012-03-29 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN337DE2012 IN2012DE00337A (ru) | 2012-02-06 | 2012-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DE00337A true IN2012DE00337A (ru) | 2015-04-10 |
Family
ID=46028019
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN337DE2012 IN2012DE00337A (ru) | 2012-02-06 | 2012-03-29 |
Country Status (4)
Country | Link |
---|---|
US (1) | US9872873B2 (ru) |
EP (1) | EP2811984B1 (ru) |
IN (1) | IN2012DE00337A (ru) |
WO (1) | WO2013117969A1 (ru) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
CN103945902B (zh) | 2011-08-30 | 2018-07-20 | 阿斯泰克斯制药公司 | 地西他滨衍生物制剂 |
US9801859B2 (en) * | 2012-09-18 | 2017-10-31 | Innopharma Licensing, Llc | Bendamustine formulations |
US9765108B2 (en) | 2012-11-19 | 2017-09-19 | Shilpa Medicare Limited | Formulation of 5-azacytidine |
CA2922099C (en) | 2013-08-27 | 2022-11-29 | Vasilios VOUDOURIS | Bendamustine pharmaceutical compositions |
CN103585168A (zh) * | 2013-11-27 | 2014-02-19 | 哈尔滨誉衡药业股份有限公司 | 一种含有盐酸吉西他滨的药物组合物 |
CN104739778A (zh) * | 2013-12-26 | 2015-07-01 | 山东新时代药业有限公司 | 一种注射用阿扎胞苷及其制备方法 |
CA2941632C (en) | 2014-03-13 | 2023-10-24 | Vasilios VOUDOURIS | Bendamustine solid dispersions and continuous infusion |
US20160095925A1 (en) * | 2014-10-01 | 2016-04-07 | Cadila Healthcare Limited | Stable formulation of azacitidine or salts thereof and their process for preparation |
AU2016287585B2 (en) * | 2015-07-02 | 2020-12-17 | Otsuka Pharmaceutical Co., Ltd. | Lyophilized pharmaceutical compositions |
CN105769775A (zh) * | 2016-03-24 | 2016-07-20 | 浙江华海药业股份有限公司 | 一种注射用阿扎胞苷的制备方法 |
JP2020529409A (ja) | 2017-08-03 | 2020-10-08 | 大塚製薬株式会社 | 薬物化合物およびその精製方法 |
CN108295034A (zh) * | 2018-03-29 | 2018-07-20 | 健进制药有限公司 | 一种注射用阿扎胞苷冻干粉针及其制备方法 |
KR20190136284A (ko) * | 2018-05-30 | 2019-12-10 | 주식회사 삼양바이오팜 | 안정한 아자시티딘-함유 약제학적 조성물의 제조방법 |
US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4684630A (en) | 1983-08-24 | 1987-08-04 | Repta Arnold J | Method of parenterally delivering drugs and related compositions |
SG144165A1 (en) | 2003-07-25 | 2008-07-29 | Wyeth Corp | Cci-779 lyophilized formulations |
US20060069060A1 (en) * | 2004-09-27 | 2006-03-30 | Sanjeev Redkar | Salts of decitabine |
US8436190B2 (en) | 2005-01-14 | 2013-05-07 | Cephalon, Inc. | Bendamustine pharmaceutical compositions |
CN101361718B (zh) | 2008-09-26 | 2013-08-28 | 深圳万乐药业有限公司 | 稳定的地西他滨冻干制剂的制备方法 |
CN101584670B (zh) * | 2009-06-19 | 2011-04-20 | 江苏奥赛康药业有限公司 | 地西他滨冻干粉针剂 |
US20110042247A1 (en) | 2009-06-25 | 2011-02-24 | Chandrasekhar Kocherlakota | Formulations of azacitidine and its derivatives |
WO2011014541A1 (en) | 2009-07-30 | 2011-02-03 | Eagle Pharmaceuticals, Inc. | Stable formulations of azacitidine |
WO2011103150A2 (en) * | 2010-02-18 | 2011-08-25 | Cephalon, Inc. | Lyophilized preparations of bendamustine |
WO2012103226A2 (en) * | 2011-01-25 | 2012-08-02 | Dr. Reddy's Laboratories Ltd. | Bendamustine formulations |
-
2012
- 2012-03-29 EP EP12719066.8A patent/EP2811984B1/en active Active
- 2012-03-29 WO PCT/IB2012/051513 patent/WO2013117969A1/en active Application Filing
- 2012-03-29 US US14/377,047 patent/US9872873B2/en active Active
- 2012-03-29 IN IN337DE2012 patent/IN2012DE00337A/en unknown
Also Published As
Publication number | Publication date |
---|---|
US9872873B2 (en) | 2018-01-23 |
US20140378407A1 (en) | 2014-12-25 |
EP2811984A1 (en) | 2014-12-17 |
EP2811984B1 (en) | 2015-08-26 |
WO2013117969A1 (en) | 2013-08-15 |
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