IN2005KO00312A - - Google Patents
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- Publication number
- IN2005KO00312A IN2005KO00312A IN312KO2005A IN2005KO00312A IN 2005KO00312 A IN2005KO00312 A IN 2005KO00312A IN 312KO2005 A IN312KO2005 A IN 312KO2005A IN 2005KO00312 A IN2005KO00312 A IN 2005KO00312A
- Authority
- IN
- India
- Prior art keywords
- enzymes
- compounds
- phospholipase
- inflammation
- pain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33459101P | 2001-12-03 | 2001-12-03 | |
| US33460501P | 2001-12-03 | 2001-12-03 | |
| US33458801P | 2001-12-03 | 2001-12-03 | |
| US41966402P | 2002-10-18 | 2002-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2005KO00312A true IN2005KO00312A (fr) | 2015-08-14 |
Family
ID=27502498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN312KO2005 IN2005KO00312A (fr) | 2001-12-03 | 2005-04-12 |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1451154B1 (fr) |
| JP (1) | JP4657605B2 (fr) |
| KR (1) | KR100973665B1 (fr) |
| CN (1) | CN100503566C (fr) |
| AR (1) | AR037684A1 (fr) |
| AT (1) | ATE384045T1 (fr) |
| AU (1) | AU2002351182B2 (fr) |
| BR (1) | BR0214672A (fr) |
| CA (1) | CA2469138C (fr) |
| CO (1) | CO5580763A2 (fr) |
| CY (1) | CY1107383T1 (fr) |
| DE (1) | DE60224707T2 (fr) |
| DK (2) | DK1451154T3 (fr) |
| EC (1) | ECSP045131A (fr) |
| ES (2) | ES2300490T3 (fr) |
| HK (2) | HK1065799A1 (fr) |
| HU (1) | HUP0402577A3 (fr) |
| IL (2) | IL162052A0 (fr) |
| IN (1) | IN2005KO00312A (fr) |
| NO (1) | NO327256B1 (fr) |
| NZ (1) | NZ533269A (fr) |
| PL (1) | PL370445A1 (fr) |
| PT (1) | PT1451154E (fr) |
| TW (1) | TWI334778B (fr) |
| WO (1) | WO2003048122A2 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
| US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
| TW200510305A (en) * | 2003-07-25 | 2005-03-16 | Wyeth Corp | Process for the preparation of CPLA2 inhibitors |
| JP2007515403A (ja) | 2003-11-17 | 2007-06-14 | ワイス | Ｎ−置換フタルイミドの調製方法 |
| HN2004000536A (es) * | 2003-12-16 | 2009-02-18 | Wyeth Corp | Un procediemiento de sintesis para la alquilacion reductiva de la posicon c-3 de indoles |
| AR048239A1 (es) | 2004-02-25 | 2006-04-12 | Wyeth Corp | Procesos para la preparacion de haluros de aril- y heteroaril-alquilsulfonilo e intermediarios de sintesis de los mismos |
| US20050244367A1 (en) * | 2004-05-03 | 2005-11-03 | Ilypsa, Inc. | Phospholipase inhibitors localized in the gastrointestinal lumen |
| AR053410A1 (es) | 2004-08-19 | 2007-05-09 | Wyeth Corp | Proceso para la sintesis de indoles n-alquilados c-2, c-3 sustituidos. compuestos intermediarios |
| PL1719507T3 (pl) | 2005-04-13 | 2010-12-31 | Cipher Pharmaceuticals Inc | Agoniści receptora beta2-adrenergicznego do leczenia chorób tkanki łącznej skóry |
| GT200600228A (es) * | 2005-05-27 | 2006-12-26 | Inhibidores de la fosfolipasa a2 citosolica | |
| MX2008000816A (es) | 2005-07-21 | 2008-03-18 | Wyeth Corp | Procedimiento para la sintesis de haluros de sulfonilo y sulfonamidas a partir de sales de acido sulfonico. |
| CA2627043A1 (fr) | 2005-11-03 | 2007-05-18 | Ilypsa, Inc. | Composes d'indole multivalents et leur utilisation en tant qu'inhibiteurs de phospholipases a2 |
| FR2899471A1 (fr) * | 2006-04-06 | 2007-10-12 | Pasteur Institut | Utilisation d'au moins un inhibiteur de la phospholipase a2 cytosolique comme medicament pour le traitement des maladies respiratoires |
| WO2007140317A2 (fr) * | 2006-05-26 | 2007-12-06 | Wyeth | Méthodes d'utilisation d'inhibiteurs de la phospholipase a2 cytosolique dans le traitement de la thrombose |
| WO2008055141A2 (fr) * | 2006-10-31 | 2008-05-08 | Wyeth | Preparations liquides d'inhibiteurs d'enzymes phospholipase |
| EP2077834A2 (fr) * | 2006-10-31 | 2009-07-15 | Wyeth | Formulations d'inhibiteurs d'enzymes phospholipase |
| KR20090125799A (ko) | 2007-03-29 | 2009-12-07 | 아스비오파마 가부시키가이샤 | Ｃｐｌａ2 저해 활성을 가지는 인돌 유도체 및 그 용도 및 제조 방법 |
| CA2722102C (fr) | 2008-04-28 | 2013-06-11 | Asahi Kasei Pharma Corporation | Derive d'acide phenylpropionique et son utilisation |
| EP2488025A4 (fr) * | 2009-10-15 | 2013-04-03 | Childrens Medical Center | Inhibiteurs de sépiaptérine réductase pour le traitement de la douleur |
| WO2012031763A1 (fr) | 2010-09-08 | 2012-03-15 | Twincore Zentrum Fuer Experimentelle Und Klinische Infektionsforschung Gmbh | Utilisation d'inhibiteurs de phospholipase a2 pour traiter ou prévenir une infection à flavivirus |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2079374C (fr) * | 1991-09-30 | 2003-08-05 | Merck Frosst Canada Incorporated | Indol (azaarylmethoxy bicyclique) comme inhibiteur de leucotriene biosynthetique |
| US5994398A (en) * | 1996-12-11 | 1999-11-30 | Elan Pharmaceuticals, Inc. | Arylsulfonamides as phospholipase A2 inhibitors |
| WO1999043654A2 (fr) * | 1998-02-25 | 1999-09-02 | Genetics Institute, Inc. | Inhibiteurs d'enzymes phospholipases |
| JP2002504539A (ja) * | 1998-02-25 | 2002-02-12 | ジェネティックス・インスチチュート・インコーポレーテッド | ホスホリパーゼ酵素の阻害剤 |
-
2002
- 2002-12-02 PL PL02370445A patent/PL370445A1/xx not_active Application Discontinuation
- 2002-12-02 DK DK02786829T patent/DK1451154T3/da active
- 2002-12-02 BR BR0214672-0A patent/BR0214672A/pt not_active Application Discontinuation
- 2002-12-02 ES ES02786829T patent/ES2300490T3/es not_active Expired - Lifetime
- 2002-12-02 DE DE60224707T patent/DE60224707T2/de not_active Expired - Lifetime
- 2002-12-02 JP JP2003549314A patent/JP4657605B2/ja not_active Expired - Lifetime
- 2002-12-02 CA CA2469138A patent/CA2469138C/fr not_active Expired - Lifetime
- 2002-12-02 TW TW091134928A patent/TWI334778B/zh not_active IP Right Cessation
- 2002-12-02 DK DK07023208.7T patent/DK1892239T3/da active
- 2002-12-02 WO PCT/US2002/038311 patent/WO2003048122A2/fr active IP Right Grant
- 2002-12-02 AU AU2002351182A patent/AU2002351182B2/en not_active Expired
- 2002-12-02 AR ARP020104643A patent/AR037684A1/es unknown
- 2002-12-02 PT PT02786829T patent/PT1451154E/pt unknown
- 2002-12-02 CN CNB028276116A patent/CN100503566C/zh not_active Expired - Lifetime
- 2002-12-02 HU HU0402577A patent/HUP0402577A3/hu unknown
- 2002-12-02 KR KR1020047008482A patent/KR100973665B1/ko active IP Right Grant
- 2002-12-02 ES ES07023208T patent/ES2401454T3/es not_active Expired - Lifetime
- 2002-12-02 IL IL16205202A patent/IL162052A0/xx unknown
- 2002-12-02 EP EP02786829A patent/EP1451154B1/fr not_active Expired - Lifetime
- 2002-12-02 NZ NZ533269A patent/NZ533269A/xx not_active IP Right Cessation
- 2002-12-02 AT AT02786829T patent/ATE384045T1/de active
-
2004
- 2004-05-19 IL IL162052A patent/IL162052A/en active IP Right Grant
- 2004-05-31 CO CO04050432A patent/CO5580763A2/es not_active Application Discontinuation
- 2004-06-03 EC EC2004005131A patent/ECSP045131A/es unknown
- 2004-06-25 NO NO20042679A patent/NO327256B1/no not_active IP Right Cessation
- 2004-11-06 HK HK04108749A patent/HK1065799A1/xx not_active IP Right Cessation
-
2005
- 2005-04-12 IN IN312KO2005 patent/IN2005KO00312A/en unknown
-
2008
- 2008-03-31 CY CY20081100371T patent/CY1107383T1/el unknown
- 2008-08-20 HK HK08109339.3A patent/HK1113798A1/xx not_active IP Right Cessation
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