IN2005DE03350A - - Google Patents
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- Publication number
- IN2005DE03350A IN2005DE03350A IN3350DE2005A IN2005DE03350A IN 2005DE03350 A IN2005DE03350 A IN 2005DE03350A IN 3350DE2005 A IN3350DE2005 A IN 3350DE2005A IN 2005DE03350 A IN2005DE03350 A IN 2005DE03350A
- Authority
- IN
- India
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03003495 | 2003-02-14 | ||
EP03007594 | 2003-04-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
IN2005DE03350A true IN2005DE03350A (es) | 2007-06-01 |
IN228043B IN228043B (es) | 2009-02-13 |
Family
ID=32870763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3350DE2005 IN228043B (es) | 2003-02-14 | 2004-02-06 |
Country Status (16)
Country | Link |
---|---|
US (2) | US20060229353A1 (es) |
EP (1) | EP1597262B1 (es) |
JP (1) | JP4795931B2 (es) |
KR (1) | KR20050098928A (es) |
CN (1) | CN1845925B (es) |
AT (1) | ATE448232T1 (es) |
AU (1) | AU2004212296B2 (es) |
BR (1) | BRPI0407234A (es) |
CA (1) | CA2515940C (es) |
DE (1) | DE602004024037D1 (es) |
ES (1) | ES2336562T3 (es) |
HK (1) | HK1096392A1 (es) |
IL (1) | IL169897A0 (es) |
IN (1) | IN228043B (es) |
MX (1) | MX272108B (es) |
WO (1) | WO2004071382A2 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2429163C (en) | 2000-11-16 | 2013-02-12 | The Regents Of The University Of California | Marine actinomycete taxon for drug fermentation and product discovery |
US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
KR20060026052A (ko) * | 2003-06-20 | 2006-03-22 | 니리어스 파마슈티컬즈, 인코퍼레이션 | 암, 염증 및 감염성 질환의 치료를 위한 [3.2.0]헤테로사이클릭 화합물 및 그 유사체의 사용방법 |
ZA200600473B (en) * | 2003-06-20 | 2007-04-25 | Univ California | Salinosporamides and methods for use thereof |
WO2005099687A2 (en) | 2004-04-09 | 2005-10-27 | President And Fellows Of Harvard College | Analogs of salinosporamide a |
NZ550910A (en) * | 2004-04-30 | 2011-06-30 | Nereus Pharmaceuticals Inc | [3.2.0] Heterocyclic compounds and methods of using the same |
US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
JP2008505956A (ja) * | 2004-07-12 | 2008-02-28 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | 真菌駆除剤および昆虫駆除剤としての置換されている2−ピロリドン誘導体 |
AU2005311572A1 (en) * | 2004-12-03 | 2006-06-08 | Nereus Pharmaceuticals, Inc. | Methods of using (3.2.0) heterocyclic compounds and analogs thereof |
CA2588923C (en) * | 2004-12-03 | 2015-02-03 | Kenneth C. Anderson | Compositions and methods for treating neoplastic diseases |
WO2006118973A2 (en) * | 2005-04-29 | 2006-11-09 | Nereus Pharmaceuticals, Inc. | Methods of using heterobyclic compounds for treatment of rectal cancer |
US7465720B2 (en) | 2005-09-12 | 2008-12-16 | President And Fellows Of Harvard College | Proteasome inhibiting β-lactam compounds |
CN102718776A (zh) | 2006-04-06 | 2012-10-10 | 尼瑞斯药品公司 | Salinosporamide a及其类似物的全合成 |
US7824698B2 (en) * | 2007-02-02 | 2010-11-02 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of Salinosporamide A |
US20080280968A1 (en) * | 2007-05-04 | 2008-11-13 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof for treating infectious diseases |
US8394816B2 (en) * | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
EP2088205A1 (en) | 2008-02-11 | 2009-08-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | PSMB10: A diagnosis marker and therapeutic target of chronic rejection. |
AU2009241635A1 (en) | 2008-03-07 | 2009-11-05 | Nereus Pharmaceuticals, Inc. | Total synthesis of Salinosporamide A and analogs thereof |
EP2276765A4 (en) | 2008-05-12 | 2011-10-19 | Nereus Pharmaceuticals Inc | SALINOSPORAMIDE DERIVATIVES AS PROTEASOMAL HEMMER |
WO2010096574A1 (en) | 2009-02-20 | 2010-08-26 | Lisanti Michael P | A method of diagnosis or prognosis of a neoplasm comprising determining the level of expression of a protein in stromal cells adjacent to the neoplasm |
US9126997B1 (en) | 2010-09-07 | 2015-09-08 | Northwestern University | Synergistic effect of glucocorticoid receptor agonists in combination with proteosome inhibitors for treating leukemia and myeloma |
EP2771489B1 (en) | 2011-10-28 | 2018-07-04 | Millennium Pharmaceuticals, Inc. | Biomarkers of response to nae inhibitors |
CN104126017A (zh) | 2011-11-11 | 2014-10-29 | 米伦纽姆医药公司 | 对蛋白酶体抑制剂的反应的生物标记 |
CN104204797B (zh) | 2012-01-24 | 2017-05-31 | 米伦纽姆医药公司 | 治疗癌症的方法 |
WO2013112881A1 (en) | 2012-01-27 | 2013-08-01 | Thomas Jefferson University | Mct protein inhibitor-related prognostic and therapeutic methods |
US10662477B2 (en) | 2012-10-01 | 2020-05-26 | Millennium Pharmaceuticals, Inc. | Biomarkers and methods to predict response to inhibitors and uses thereof |
WO2014172627A1 (en) | 2013-04-19 | 2014-10-23 | Thomas Jefferson University | Caveolin-1 related methods for treating glioblastoma with temozolomide |
EP3339291A1 (en) | 2016-12-22 | 2018-06-27 | Vita Api | Proteasome inhibiting ss-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6335358B1 (en) * | 1995-04-12 | 2002-01-01 | President And Fellows Of Harvard College | Lactacystin analogs |
CA2429163C (en) * | 2000-11-16 | 2013-02-12 | The Regents Of The University Of California | Marine actinomycete taxon for drug fermentation and product discovery |
-
2004
- 2004-02-06 WO PCT/EP2004/001097 patent/WO2004071382A2/en active Application Filing
- 2004-02-06 BR BR0407234-0A patent/BRPI0407234A/pt not_active IP Right Cessation
- 2004-02-06 CA CA2515940A patent/CA2515940C/en not_active Expired - Fee Related
- 2004-02-06 JP JP2006501755A patent/JP4795931B2/ja not_active Expired - Fee Related
- 2004-02-06 US US10/545,449 patent/US20060229353A1/en not_active Abandoned
- 2004-02-06 DE DE602004024037T patent/DE602004024037D1/de not_active Expired - Lifetime
- 2004-02-06 ES ES04708731T patent/ES2336562T3/es not_active Expired - Lifetime
- 2004-02-06 EP EP04708731A patent/EP1597262B1/en not_active Expired - Lifetime
- 2004-02-06 IN IN3350DE2005 patent/IN228043B/en unknown
- 2004-02-06 AU AU2004212296A patent/AU2004212296B2/en not_active Ceased
- 2004-02-06 KR KR1020057014935A patent/KR20050098928A/ko active IP Right Grant
- 2004-02-06 MX MXPA05008478 patent/MX272108B/es active IP Right Grant
- 2004-02-06 CN CN2004800093759A patent/CN1845925B/zh not_active Expired - Fee Related
- 2004-02-06 AT AT04708731T patent/ATE448232T1/de not_active IP Right Cessation
-
2005
- 2005-07-26 IL IL169897A patent/IL169897A0/en unknown
-
2007
- 2007-03-30 HK HK07103474.2A patent/HK1096392A1/xx not_active IP Right Cessation
-
2009
- 2009-01-08 US US12/350,696 patent/US20110015248A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BRPI0407234A (pt) | 2006-01-31 |
EP1597262B1 (en) | 2009-11-11 |
AU2004212296B2 (en) | 2010-06-17 |
EP1597262A2 (en) | 2005-11-23 |
ES2336562T3 (es) | 2010-04-14 |
CA2515940C (en) | 2011-12-06 |
JP4795931B2 (ja) | 2011-10-19 |
CA2515940A1 (en) | 2004-08-26 |
JP2006517934A (ja) | 2006-08-03 |
WO2004071382A3 (en) | 2005-01-06 |
MXPA05008478A (es) | 2005-10-18 |
ATE448232T1 (de) | 2009-11-15 |
KR20050098928A (ko) | 2005-10-12 |
WO2004071382A2 (en) | 2004-08-26 |
DE602004024037D1 (de) | 2009-12-24 |
AU2004212296A1 (en) | 2004-08-26 |
HK1096392A1 (en) | 2007-06-01 |
IL169897A0 (en) | 2007-07-04 |
CN1845925A (zh) | 2006-10-11 |
US20060229353A1 (en) | 2006-10-12 |
US20110015248A1 (en) | 2011-01-20 |
CN1845925B (zh) | 2010-11-03 |
MX272108B (es) | 2009-11-25 |
IN228043B (es) | 2009-02-13 |