IN181859B - - Google Patents

Info

Publication number
IN181859B
IN181859B IN946MA1996A IN181859B IN 181859 B IN181859 B IN 181859B IN 946MA1996 A IN946MA1996 A IN 946MA1996A IN 181859 B IN181859 B IN 181859B
Authority
IN
India
Prior art keywords
protein solution
treatment
protein
clarification
purification
Prior art date
Application number
Other languages
English (en)
Inventor
Terben Kjaersgaard Nielsen
Mads Aage Laustsen
Niels-Viktor Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IN181859B publication Critical patent/IN181859B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN946MA1996 1995-06-02 1996-06-03 IN181859B (en:Method)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK62695 1995-06-02

Publications (1)

Publication Number Publication Date
IN181859B true IN181859B (en:Method) 1998-10-03

Family

ID=8095720

Family Applications (1)

Application Number Title Priority Date Filing Date
IN946MA1996 IN181859B (en:Method) 1995-06-02 1996-06-03

Country Status (9)

Country Link
EP (1) EP0828753B1 (en:Method)
JP (1) JPH11511118A (en:Method)
CN (1) CN1114613C (en:Method)
AT (1) ATE235506T1 (en:Method)
AU (1) AU5996996A (en:Method)
DE (1) DE69626976T2 (en:Method)
DK (1) DK0828753T3 (en:Method)
IN (1) IN181859B (en:Method)
WO (1) WO1996038469A1 (en:Method)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2810667B1 (fr) * 2000-06-23 2004-09-03 Warner Lambert Co Procede d'isolement et de purification d'une proteine, et proteine obtenue
PT1370674E (pt) 2001-02-21 2011-08-31 Verenium Corp Enzimas que possuem actividade de alfa-amilase e processos para a sua utilização
US7659102B2 (en) 2001-02-21 2010-02-09 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
US20030013172A1 (en) * 2001-05-14 2003-01-16 Joel Gerendash Novel methods of enzyme purification
AU2002316811A1 (en) 2001-06-28 2003-03-03 Novo Nordisk A/S Stable formulation of modified glp-1
CN100487114C (zh) * 2001-12-11 2009-05-13 诺维信公司 从发酵液收获晶体
US7118891B2 (en) 2001-12-11 2006-10-10 Novozymes A/S Crystal harvest from fermentation broth
WO2004091544A2 (en) 2003-03-06 2004-10-28 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
EP1633391B1 (en) 2003-06-03 2011-10-19 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
JP4936884B2 (ja) 2003-06-03 2012-05-23 ノボ・ノルデイスク・エー／エス 安定化された薬学的ペプチド組成物
MXPA06005581A (es) 2003-11-20 2006-08-11 Novo Nordisk As Formulaciones de peptidos que contienen propilenglicol que son optimas para la produccion y uso en dispositivos de inyeccion.
EP1789434B1 (en) 2004-08-31 2013-11-20 Novo Nordisk A/S Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
MX2007005521A (es) 2004-11-12 2007-05-18 Novo Nordisk As Formulaciones estables de peptidos insulinotropicos.
WO2007035283A1 (en) * 2005-09-15 2007-03-29 Wyeth Protein floculation using salts
MX2009006782A (es) 2006-12-21 2009-09-21 Verenium Corp Amilasas y glucoamilasas, acidos nucleicos que las codifican y metodos para formarlas y usarlas.
US20120252066A1 (en) * 2011-03-29 2012-10-04 Heng Meng H Methods of foam control
US20150291656A1 (en) 2012-11-01 2015-10-15 Novozymes A/S Method for removal of dna
CN105745217A (zh) 2013-11-19 2016-07-06 凯米罗总公司 减少生物技术液体的颜色的方法
SG11202000940XA (en) 2017-08-24 2020-02-27 Novo Nordisk As Glp-1 compositions and uses thereof
CN108949703A (zh) * 2018-06-28 2018-12-07 大连理工大学 一种半纤维小体类似物粗提纯方法
WO2020249546A1 (en) 2019-06-13 2020-12-17 Basf Se Method of recovering a protein from fermentation broth using a divalent cation
TWI878456B (zh) 2020-02-18 2025-04-01 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
MX2023003276A (es) 2020-09-22 2023-05-03 Basf Se Método para recuperar una proteína de un caldo de fermentación que comprende un alto grado de células lisadas.
CN112500471B (zh) * 2020-12-22 2022-09-27 中美华世通生物医药科技(武汉)股份有限公司 一种制备高澄清度蛋白琥珀酸铁的方法
EP4565711A1 (en) 2022-08-02 2025-06-11 Basf Se Stabilized protein production process using bacillus host cells with salt feed

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795586A (en) * 1969-08-11 1974-03-05 Pabst Brewing Co Recovery of enzymes
PL270368A1 (en) * 1987-01-30 1988-10-13 Int Minerals & Chem Corp Method for recovery of somatotropins from diluted water solutions
US4894444A (en) * 1987-07-16 1990-01-16 Merck & Co., Inc. Recovery and purification of immunogens from immunogen-alum complexes
DE3915277A1 (de) * 1989-05-10 1990-11-15 Henkel Kgaa Verfahren zur reinigung von enzymfluessigkonzentraten
DE4037530A1 (de) * 1990-11-26 1992-05-27 Henkel Kgaa Faellungsverfahren fuer exocellulaere proteine
DK91092D0 (en:Method) * 1992-07-10 1992-07-10 Novo Nordisk As

Also Published As

Publication number Publication date
EP0828753A1 (en) 1998-03-18
CN1186498A (zh) 1998-07-01
DK0828753T3 (da) 2003-06-30
AU5996996A (en) 1996-12-18
ATE235506T1 (de) 2003-04-15
JPH11511118A (ja) 1999-09-28
CN1114613C (zh) 2003-07-16
EP0828753B1 (en) 2003-03-26
DE69626976T2 (de) 2004-03-04
DE69626976D1 (de) 2003-04-30
WO1996038469A1 (en) 1996-12-05

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