IN181859B - - Google Patents

Info

Publication number
IN181859B
IN181859B IN946MA1996A IN181859B IN 181859 B IN181859 B IN 181859B IN 946MA1996 A IN946MA1996 A IN 946MA1996A IN 181859 B IN181859 B IN 181859B
Authority
IN
India
Prior art keywords
protein solution
treatment
protein
clarification
purification
Prior art date
Application number
Other languages
English (en)
Inventor
Terben Kjaersgaard Nielsen
Mads Aage Laustsen
Niels-Viktor Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IN181859B publication Critical patent/IN181859B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN946MA1996 1995-06-02 1996-06-03 IN181859B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK62695 1995-06-02

Publications (1)

Publication Number Publication Date
IN181859B true IN181859B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) 1998-10-03

Family

ID=8095720

Family Applications (1)

Application Number Title Priority Date Filing Date
IN946MA1996 IN181859B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) 1995-06-02 1996-06-03

Country Status (9)

Country Link
EP (1) EP0828753B1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
JP (1) JPH11511118A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
CN (1) CN1114613C (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
AT (1) ATE235506T1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
AU (1) AU5996996A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
DE (1) DE69626976T2 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
DK (1) DK0828753T3 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
IN (1) IN181859B (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)
WO (1) WO1996038469A1 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2810667B1 (fr) * 2000-06-23 2004-09-03 Warner Lambert Co Procede d'isolement et de purification d'une proteine, et proteine obtenue
CA2438884C (en) 2001-02-21 2014-01-28 Diversa Corporation Enzymes having alpha amylase activity and methods of use thereof
US7659102B2 (en) 2001-02-21 2010-02-09 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
US20030013172A1 (en) * 2001-05-14 2003-01-16 Joel Gerendash Novel methods of enzyme purification
JP5562510B2 (ja) 2001-06-28 2014-07-30 ノヴォ ノルディスク アー/エス 修飾glp−1の安定な処方剤
US7118891B2 (en) 2001-12-11 2006-10-10 Novozymes A/S Crystal harvest from fermentation broth
WO2003050274A2 (en) * 2001-12-11 2003-06-19 Novozymes A/S Process for harvesting crystalline particles from fermentation broth
MXPA05009566A (es) 2003-03-06 2005-12-14 Diversa Corp Amilasas, acidos nucleicos que las codifican, y metodos para hacerlas y usarlas.
JP2007524592A (ja) 2003-06-03 2007-08-30 ノボ・ノルデイスク・エー/エス 安定化された薬学的ペプチド組成物
BRPI0410972C1 (pt) 2003-06-03 2021-05-25 Novo Nordisk As método para aumentar a vida de armazenagem de uma composição farmacêutica, composição farmacêutica, e, método para tratamento de hiperglicemia
DK3300721T4 (da) 2003-11-20 2025-03-03 Novo Nordisk As Propylenglycol-holdige peptidformuleringer hvilke er optimale til fremstilling og til anvendelse i injektionsindretninger
WO2006024631A2 (en) 2004-08-31 2006-03-09 Novo Nordisk A/S Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
BRPI0517341A (pt) 2004-11-12 2008-10-07 Novo Nordisk As composição farmacêutica estável em prateleira, métodos para a preparação de uma composição farmacêutica, para o tratamento de hiperglicemia, para o tratamento de obesidade, deficiência de célula beta, igt ou dislipidemia, para a preparação de uma solução estável de um composto glp-1, para a preparação de um composto glp-1 estável e para a preparação de uma composição farmacêutica estável em prateleira de um composto glp-1, solução estável de um composto glp-1, e, uso de uma solução estável de um composto glp-1
TW200801039A (en) 2005-09-15 2008-01-01 Wyeth Corp Separation methods
EP3101128B1 (en) 2006-12-21 2019-04-10 BASF Enzymes LLC Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
US20120252066A1 (en) * 2011-03-29 2012-10-04 Heng Meng H Methods of foam control
CN104797590A (zh) 2012-11-01 2015-07-22 诺维信公司 用于去除dna的方法
EP3071589B1 (en) 2013-11-19 2018-03-14 Kemira OYJ Method for reducing colour of a biotechnological liquid
CN118903386A (zh) 2017-08-24 2024-11-08 诺和诺德股份有限公司 Glp-1组合物及其用途
CN108949703A (zh) * 2018-06-28 2018-12-07 大连理工大学 一种半纤维小体类似物粗提纯方法
MX2021015364A (es) 2019-06-13 2022-01-24 Basf Se Metodo de recuperacion de una proteina de un caldo de fermentacion mediante el uso de un cation divalente.
CN115135304A (zh) 2020-02-18 2022-09-30 诺和诺德股份有限公司 Glp-1组合物及其用途
BR112023005111A2 (pt) 2020-09-22 2023-04-18 Basf Se Método para recuperar uma proteína de interesse de um caldo de fermentação bacteriana, e, uso de pelo menos um floculante
CN112500471B (zh) * 2020-12-22 2022-09-27 中美华世通生物医药科技(武汉)股份有限公司 一种制备高澄清度蛋白琥珀酸铁的方法
WO2024028338A1 (en) 2022-08-02 2024-02-08 Basf Se Stabilized protein production process using bacillus host cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795586A (en) * 1969-08-11 1974-03-05 Pabst Brewing Co Recovery of enzymes
DD270466A5 (de) * 1987-01-30 1989-08-02 �������������@��������@�K@���������@����Kk�� Verfahren zur rueckgewinnung von somatropinen aus verduennten waessrigen loesungen
US4894444A (en) * 1987-07-16 1990-01-16 Merck & Co., Inc. Recovery and purification of immunogens from immunogen-alum complexes
DE3915277A1 (de) * 1989-05-10 1990-11-15 Henkel Kgaa Verfahren zur reinigung von enzymfluessigkonzentraten
DE4037530A1 (de) * 1990-11-26 1992-05-27 Henkel Kgaa Faellungsverfahren fuer exocellulaere proteine
DK91092D0 (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) * 1992-07-10 1992-07-10 Novo Nordisk As

Also Published As

Publication number Publication date
JPH11511118A (ja) 1999-09-28
EP0828753B1 (en) 2003-03-26
WO1996038469A1 (en) 1996-12-05
EP0828753A1 (en) 1998-03-18
DE69626976D1 (de) 2003-04-30
CN1114613C (zh) 2003-07-16
DE69626976T2 (de) 2004-03-04
ATE235506T1 (de) 2003-04-15
CN1186498A (zh) 1998-07-01
AU5996996A (en) 1996-12-18
DK0828753T3 (da) 2003-06-30

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