IL99605A0 - 4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticals - Google Patents
4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticalsInfo
- Publication number
- IL99605A0 IL99605A0 IL99605A IL9960591A IL99605A0 IL 99605 A0 IL99605 A0 IL 99605A0 IL 99605 A IL99605 A IL 99605A IL 9960591 A IL9960591 A IL 9960591A IL 99605 A0 IL99605 A0 IL 99605A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceuticals
- preparation
- carboxylic acids
- substituted pyridine
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4031000A DE4031000A1 (de) | 1990-10-01 | 1990-10-01 | 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL99605A0 true IL99605A0 (en) | 1992-08-18 |
Family
ID=6415345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL99605A IL99605A0 (en) | 1990-10-01 | 1991-09-27 | 4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticals |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0479177A3 (fr) |
| JP (1) | JPH04247070A (fr) |
| KR (1) | KR920007999A (fr) |
| CN (1) | CN1060655A (fr) |
| AU (1) | AU8485291A (fr) |
| BG (1) | BG95162A (fr) |
| BR (1) | BR9104205A (fr) |
| CA (1) | CA2052510A1 (fr) |
| CS (1) | CS299191A3 (fr) |
| DE (1) | DE4031000A1 (fr) |
| FI (1) | FI914556A (fr) |
| HU (1) | HUT59103A (fr) |
| IE (1) | IE913435A1 (fr) |
| IL (1) | IL99605A0 (fr) |
| MA (1) | MA22313A1 (fr) |
| MX (1) | MX9101347A (fr) |
| NO (1) | NO913834L (fr) |
| PL (1) | PL291881A1 (fr) |
| PT (1) | PT99132A (fr) |
| ZA (1) | ZA917805B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0617020A1 (fr) * | 1992-04-02 | 1994-09-28 | Shudo, Koichi, Prof. Dr. | Acides carboxyliques ayant une activité analogue à l'acide rétinoique |
| DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| TW200626154A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| BRPI0515478A (pt) | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e seu uso como mediadores de estearoil-coa-desaturase |
| AU2005329423A1 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| TW200626155A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| WO2006034279A1 (fr) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Derives heterocycliques et leur utilisation comme agents therapeutiques |
| CN101083982A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物 |
| CN101084207A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途 |
| BRPI0611187A2 (pt) | 2005-06-03 | 2010-08-24 | Xenon Pharmaceuticals Inc | derivados aminotiazàis como inibidores da estearoil-coa desaturase humana |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3703959A1 (de) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| DE3703962A1 (de) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| ATE113036T1 (de) * | 1988-08-04 | 1994-11-15 | Hoechst Ag | Verbessertes verfahren zur herstellung von n,n- bis(alkoxyalkyl)-pyridin -2,4- dicarbonsäurediamiden. |
-
1990
- 1990-10-01 DE DE4031000A patent/DE4031000A1/de not_active Withdrawn
-
1991
- 1991-09-24 BG BG095162A patent/BG95162A/bg unknown
- 1991-09-27 FI FI914556A patent/FI914556A/fi unknown
- 1991-09-27 IL IL99605A patent/IL99605A0/xx unknown
- 1991-09-30 CA CA002052510A patent/CA2052510A1/fr not_active Abandoned
- 1991-09-30 HU HU913119A patent/HUT59103A/hu unknown
- 1991-09-30 ZA ZA917805A patent/ZA917805B/xx unknown
- 1991-09-30 JP JP3250719A patent/JPH04247070A/ja active Pending
- 1991-09-30 AU AU84852/91A patent/AU8485291A/en not_active Abandoned
- 1991-09-30 CN CN91109400A patent/CN1060655A/zh active Pending
- 1991-09-30 BR BR919104205A patent/BR9104205A/pt unknown
- 1991-09-30 CS CS912991A patent/CS299191A3/cs unknown
- 1991-09-30 PL PL29188191A patent/PL291881A1/xx unknown
- 1991-09-30 KR KR1019910017066A patent/KR920007999A/ko not_active Application Discontinuation
- 1991-09-30 IE IE343591A patent/IE913435A1/en not_active Application Discontinuation
- 1991-09-30 MX MX9101347A patent/MX9101347A/es unknown
- 1991-09-30 NO NO91913834A patent/NO913834L/no unknown
- 1991-09-30 EP EP19910116632 patent/EP0479177A3/de not_active Withdrawn
- 1991-10-01 PT PT99132A patent/PT99132A/pt not_active Application Discontinuation
- 1991-10-01 MA MA22593A patent/MA22313A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA22313A1 (fr) | 1992-07-01 |
| CA2052510A1 (fr) | 1992-04-02 |
| MX9101347A (es) | 1992-06-05 |
| PT99132A (pt) | 1992-09-30 |
| EP0479177A3 (en) | 1992-10-28 |
| HU913119D0 (en) | 1992-01-28 |
| DE4031000A1 (de) | 1992-04-09 |
| PL291881A1 (en) | 1992-06-15 |
| CS299191A3 (en) | 1992-06-17 |
| JPH04247070A (ja) | 1992-09-03 |
| NO913834L (no) | 1992-04-02 |
| BG95162A (bg) | 1993-12-24 |
| CN1060655A (zh) | 1992-04-29 |
| KR920007999A (ko) | 1992-05-27 |
| AU8485291A (en) | 1992-04-02 |
| FI914556A0 (fi) | 1991-09-27 |
| NO913834D0 (no) | 1991-09-30 |
| ZA917805B (en) | 1992-05-27 |
| HUT59103A (en) | 1992-04-28 |
| BR9104205A (pt) | 1992-06-02 |
| FI914556A (fi) | 1992-04-02 |
| IE913435A1 (en) | 1992-04-08 |
| EP0479177A2 (fr) | 1992-04-08 |
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