IL99605A0 - 4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticals - Google Patents
4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticalsInfo
- Publication number
- IL99605A0 IL99605A0 IL99605A IL9960591A IL99605A0 IL 99605 A0 IL99605 A0 IL 99605A0 IL 99605 A IL99605 A IL 99605A IL 9960591 A IL9960591 A IL 9960591A IL 99605 A0 IL99605 A0 IL 99605A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceuticals
- preparation
- carboxylic acids
- substituted pyridine
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4031000A DE4031000A1 (de) | 1990-10-01 | 1990-10-01 | 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL99605A0 true IL99605A0 (en) | 1992-08-18 |
Family
ID=6415345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL99605A IL99605A0 (en) | 1990-10-01 | 1991-09-27 | 4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticals |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0479177A3 (xx) |
| JP (1) | JPH04247070A (xx) |
| KR (1) | KR920007999A (xx) |
| CN (1) | CN1060655A (xx) |
| AU (1) | AU8485291A (xx) |
| BR (1) | BR9104205A (xx) |
| CA (1) | CA2052510A1 (xx) |
| CS (1) | CS299191A3 (xx) |
| DE (1) | DE4031000A1 (xx) |
| FI (1) | FI914556A (xx) |
| HU (1) | HUT59103A (xx) |
| IE (1) | IE913435A1 (xx) |
| IL (1) | IL99605A0 (xx) |
| MA (1) | MA22313A1 (xx) |
| MX (1) | MX9101347A (xx) |
| NO (1) | NO913834L (xx) |
| PL (1) | PL291881A1 (xx) |
| PT (1) | PT99132A (xx) |
| ZA (1) | ZA917805B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0617020A1 (en) * | 1992-04-02 | 1994-09-28 | Shudo, Koichi, Prof. Dr. | Carboxylic acid derivatives having retinoic acid-like activity |
| DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| BRPI0515489A (pt) | 2004-09-20 | 2008-07-29 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e sua utilização como inibidores de estearoil-coa desaturase |
| EP1799668A1 (en) | 2004-09-20 | 2007-06-27 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase |
| AR051092A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa |
| AU2005329423A1 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| BRPI0515500A (pt) | 2004-09-20 | 2008-07-29 | Xenon Pharmaceuticals Inc | derivados piridazina para inibição de estearoil-coa-desaturase |
| JP5043668B2 (ja) | 2004-09-20 | 2012-10-10 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環誘導体および治療薬としてのそれらの使用 |
| US7919496B2 (en) | 2004-09-20 | 2011-04-05 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes |
| CN101208089A (zh) | 2005-06-03 | 2008-06-25 | 泽农医药公司 | 氨基噻唑衍生物作为人硬酯酰-CoA去饱和酶抑制剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3703962A1 (de) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| DE3703959A1 (de) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| EP0353668B1 (de) * | 1988-08-04 | 1994-10-19 | Hoechst Aktiengesellschaft | Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden |
-
1990
- 1990-10-01 DE DE4031000A patent/DE4031000A1/de not_active Withdrawn
-
1991
- 1991-09-27 IL IL99605A patent/IL99605A0/xx unknown
- 1991-09-27 FI FI914556A patent/FI914556A/fi unknown
- 1991-09-30 CN CN91109400A patent/CN1060655A/zh active Pending
- 1991-09-30 NO NO91913834A patent/NO913834L/no unknown
- 1991-09-30 ZA ZA917805A patent/ZA917805B/xx unknown
- 1991-09-30 BR BR919104205A patent/BR9104205A/pt unknown
- 1991-09-30 CS CS912991A patent/CS299191A3/cs unknown
- 1991-09-30 EP EP19910116632 patent/EP0479177A3/de not_active Withdrawn
- 1991-09-30 PL PL29188191A patent/PL291881A1/xx unknown
- 1991-09-30 AU AU84852/91A patent/AU8485291A/en not_active Abandoned
- 1991-09-30 CA CA002052510A patent/CA2052510A1/en not_active Abandoned
- 1991-09-30 IE IE343591A patent/IE913435A1/en not_active Application Discontinuation
- 1991-09-30 HU HU913119A patent/HUT59103A/hu unknown
- 1991-09-30 JP JP3250719A patent/JPH04247070A/ja active Pending
- 1991-09-30 KR KR1019910017066A patent/KR920007999A/ko not_active Application Discontinuation
- 1991-09-30 MX MX9101347A patent/MX9101347A/es unknown
- 1991-10-01 MA MA22593A patent/MA22313A1/fr unknown
- 1991-10-01 PT PT99132A patent/PT99132A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO913834L (no) | 1992-04-02 |
| CS299191A3 (en) | 1992-06-17 |
| CA2052510A1 (en) | 1992-04-02 |
| NO913834D0 (no) | 1991-09-30 |
| FI914556A0 (fi) | 1991-09-27 |
| HU913119D0 (en) | 1992-01-28 |
| AU8485291A (en) | 1992-04-02 |
| PL291881A1 (en) | 1992-06-15 |
| IE913435A1 (en) | 1992-04-08 |
| EP0479177A3 (en) | 1992-10-28 |
| JPH04247070A (ja) | 1992-09-03 |
| BR9104205A (pt) | 1992-06-02 |
| PT99132A (pt) | 1992-09-30 |
| HUT59103A (en) | 1992-04-28 |
| MX9101347A (es) | 1992-06-05 |
| CN1060655A (zh) | 1992-04-29 |
| MA22313A1 (fr) | 1992-07-01 |
| DE4031000A1 (de) | 1992-04-09 |
| EP0479177A2 (de) | 1992-04-08 |
| KR920007999A (ko) | 1992-05-27 |
| FI914556A (fi) | 1992-04-02 |
| ZA917805B (en) | 1992-05-27 |
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