IL98849A0 - (2r)-2-(di-(2-propyl)phosphonylmethoxy)-3-p-toluenesulfonyloxy-1-trimethylacetoxypropane,its preparation and use - Google Patents

(2r)-2-(di-(2-propyl)phosphonylmethoxy)-3-p-toluenesulfonyloxy-1-trimethylacetoxypropane,its preparation and use

Info

Publication number
IL98849A0
IL98849A0 IL98849A IL9884991A IL98849A0 IL 98849 A0 IL98849 A0 IL 98849A0 IL 98849 A IL98849 A IL 98849A IL 9884991 A IL9884991 A IL 9884991A IL 98849 A0 IL98849 A0 IL 98849A0
Authority
IL
Israel
Prior art keywords
trimethylacetoxypropane
phosphonylmethoxy
toluenesulfonyloxy
propyl
preparation
Prior art date
Application number
IL98849A
Other languages
English (en)
Original Assignee
Ceskoslovenska Akademie Ved
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceskoslovenska Akademie Ved filed Critical Ceskoslovenska Akademie Ved
Publication of IL98849A0 publication Critical patent/IL98849A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL98849A 1990-08-06 1991-07-15 (2r)-2-(di-(2-propyl)phosphonylmethoxy)-3-p-toluenesulfonyloxy-1-trimethylacetoxypropane,its preparation and use IL98849A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS903871A CS387190A3 (en) 1990-08-06 1990-08-06 (2r)-2-/di(2-propyl)phosphonylmethoxy/-3-p-toluenesulfonyloxy -1- trimethylacetoxypropane and process for preparing thereof

Publications (1)

Publication Number Publication Date
IL98849A0 true IL98849A0 (en) 1992-07-15

Family

ID=5380072

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98849A IL98849A0 (en) 1990-08-06 1991-07-15 (2r)-2-(di-(2-propyl)phosphonylmethoxy)-3-p-toluenesulfonyloxy-1-trimethylacetoxypropane,its preparation and use

Country Status (13)

Country Link
US (2) US5130427A (cs)
EP (1) EP0470809A1 (cs)
JP (1) JP2955402B2 (cs)
AU (1) AU8149291A (cs)
CA (1) CA2046755C (cs)
CS (1) CS387190A3 (cs)
FI (1) FI913702L (cs)
IE (1) IE71217B1 (cs)
IL (1) IL98849A0 (cs)
NO (1) NO913035L (cs)
NZ (1) NZ239131A (cs)
PT (1) PT98590B (cs)
ZA (1) ZA915932B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ284678B6 (cs) * 1991-05-20 1999-01-13 Ústav Organické Chemie A Biochemie Avčr Di(2-propyl)estery 1-fluor-2-fosfonomethoxy-3-p -toluensulfonyloxypropanů, způsob jejich přípravy a použití
US6057305A (en) 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
JP2532818B2 (ja) 1993-02-01 1996-09-11 松下電器産業株式会社 対物レンズおよび光ヘッド装置
US5502177A (en) 1993-09-17 1996-03-26 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
US6949640B2 (en) * 2000-02-18 2005-09-27 Southern Research Institute Method for synthesizing 2-chloro-9-(2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine
CZ304886B6 (cs) 2000-07-21 2015-01-07 Gilead Sciences, Inc. Prekurzory léčiv na bázi fosfonátových analogů nukleotidů a způsoby jejich výběru a přípravy
WO2003095665A2 (en) * 2002-05-13 2003-11-20 Metabasis Therapeutics, Inc. Pmea and pmpa cyclic producing synthesis
EP1532157A4 (en) * 2002-05-13 2009-02-25 Metabasis Therapeutics Inc NEW PRODRUGS FROM PMEA TO PHOSPHONIC ACID BASE AND ITS ANALOG
JP5142716B2 (ja) * 2004-06-08 2013-02-13 リガンド・ファーマシューティカルズ・インコーポレイテッド サイクリックエステルのルイス酸介在合成法
WO2012079035A1 (en) 2010-12-10 2012-06-14 Sigmapharm Laboratories, Llc Highly stable compositions of orally active nucleotide analogues or orally active nucleotide analogue prodrugs
ES2734495T3 (es) 2011-12-22 2019-12-10 Geron Corp Análogos de guanina como sustratos de telomerasa y afectores de la longitud de los telómeros
EP3105238A4 (en) 2014-02-13 2017-11-08 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
EP3164136A4 (en) 2014-07-02 2018-04-04 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
CA3087932A1 (en) 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof
JP7151348B2 (ja) * 2018-10-03 2022-10-12 日本製鉄株式会社 金属板用塗料およびこれを用いた塗装金属板の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868187A (en) * 1980-09-16 1989-09-19 Syntex (U.S.A.) Inc. Anti-viral N-substituted pyrimidines
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
CS233665B1 (en) * 1983-01-06 1985-03-14 Antonin Holy Processing of isomere o-phosphonylmethylderivative of anantiomere racemic vicinal diene
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
AU8092587A (en) * 1986-11-18 1988-05-19 Bristol-Myers Squibb Company Synthesis of purin-9-ylalkylenoxymethyl phosphonic acids
US4927830A (en) * 1988-04-08 1990-05-22 The Regents Of The University Of Michigan Acyclic pyrrolo[2,3-D]pyrimidine analogs as antiviral agents
US4968686A (en) * 1988-04-08 1990-11-06 The Regents Of The University Of Michigan Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents
AU653552B2 (en) * 1990-08-10 1994-10-06 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Novel process for the preparation of nucleotides

Also Published As

Publication number Publication date
USRE35558E (en) 1997-07-08
CS276072B6 (en) 1992-03-18
PT98590B (pt) 1999-04-30
CA2046755C (en) 2002-02-12
JPH05230087A (ja) 1993-09-07
IE912758A1 (en) 1992-02-12
ZA915932B (en) 1992-04-29
FI913702A7 (fi) 1992-02-07
NO913035D0 (no) 1991-08-05
CS387190A3 (en) 1992-03-18
EP0470809A1 (en) 1992-02-12
IE71217B1 (en) 1997-02-12
JP2955402B2 (ja) 1999-10-04
AU8149291A (en) 1992-02-13
CA2046755A1 (en) 1992-02-07
NO913035L (no) 1992-02-07
US5130427A (en) 1992-07-14
PT98590A (pt) 1992-06-30
FI913702L (fi) 1992-02-07
NZ239131A (en) 1994-04-27
FI913702A0 (fi) 1991-08-02

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