EP0536311A4 - Compositions comprising vitamin d precursors, analogs thereof and their use - Google Patents

Compositions comprising vitamin d precursors, analogs thereof and their use

Info

Publication number
EP0536311A4
EP0536311A4 EP19910913426 EP91913426A EP0536311A4 EP 0536311 A4 EP0536311 A4 EP 0536311A4 EP 19910913426 EP19910913426 EP 19910913426 EP 91913426 A EP91913426 A EP 91913426A EP 0536311 A4 EP0536311 A4 EP 0536311A4
Authority
EP
European Patent Office
Prior art keywords
analogs
precursors
vitamin
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910913426
Other versions
EP0536311A1 (en
Inventor
Michael F. Holick
Zhiren Lu
Xia Quan Tian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston University
Original Assignee
Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/541,812 external-priority patent/US5167953A/en
Priority claimed from US07/541,813 external-priority patent/US5194248A/en
Application filed by Boston University filed Critical Boston University
Priority claimed from CA002085632A external-priority patent/CA2085632A1/en
Publication of EP0536311A1 publication Critical patent/EP0536311A1/en
Publication of EP0536311A4 publication Critical patent/EP0536311A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19910913426 1990-06-21 1991-06-21 Compositions comprising vitamin d precursors, analogs thereof and their use Withdrawn EP0536311A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US541813 1983-10-13
US07/541,812 US5167953A (en) 1990-06-21 1990-06-21 Compositions comprising tachysteral and the use thereof to provide vitamin D
US541812 1990-06-21
US07/541,813 US5194248A (en) 1990-06-21 1990-06-21 Compositions comprising vitamin D analog precursors and the use thereof
US59393490A 1990-10-04 1990-10-04
US593934 1990-10-04
CA002085632A CA2085632A1 (en) 1990-06-21 1992-12-17 Compositions comprising vitamin d precursors, analogs thereof and their use

Publications (2)

Publication Number Publication Date
EP0536311A1 EP0536311A1 (en) 1993-04-14
EP0536311A4 true EP0536311A4 (en) 1993-05-19

Family

ID=27426992

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910913426 Withdrawn EP0536311A4 (en) 1990-06-21 1991-06-21 Compositions comprising vitamin d precursors, analogs thereof and their use

Country Status (2)

Country Link
EP (1) EP0536311A4 (en)
WO (1) WO1991019479A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328871A1 (en) * 1993-08-27 1995-03-02 Beiersdorf Ag Means against sensitive, hyper-reactive skin conditions, atopic dermatitis, pruritus, psoriasis prurigo, photodermatoses and ichthyosis
US5476661A (en) * 1994-10-21 1995-12-19 Elizabeth Arden Co., Division Of Conopco, Inc. Compositions for topical application to skin, hair and nails
FR2734721B1 (en) * 1995-06-02 1997-08-14 Clarins DAY COSMETIC PREPARATION ACTIVATED BY LIGHT AND INTENDED TO FIGHT AGAINST SKIN AGING
TWI247001B (en) 1996-07-01 2006-01-11 Chugai Pharmaceutical Co Ltd The method for purifying vitamin d derivatives and its crystalline products
GB202202031D0 (en) 2022-02-16 2022-03-30 Dr Weller Ltd Compositions for Vitamin D production

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2301538A1 (en) * 1975-02-21 1976-09-17 Upjohn Co PROCESS FOR PREPARING 9B, 10A-CHOLESTA-5,7-DIENE-3B, 25-DIOL
US4749710A (en) * 1985-05-01 1988-06-07 Hoffmann-La Roche Inc. Immunosuppressive agents
DD285348A5 (en) * 1988-03-21 1990-12-12 Veb Jenapharm,Dd PROCESS FOR PREPARING 1S-25-DIHYDROXY CHOLECALCIFEROL

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3702810A (en) * 1971-03-02 1972-11-14 Wisconsin Alumni Res Found Photochemical method for preparing 25-hydroxytachysterol3
US4230701A (en) * 1979-03-21 1980-10-28 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
US4335120A (en) * 1979-03-21 1982-06-15 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
US4310511A (en) * 1980-10-02 1982-01-12 Massachusetts General Hospital Sunscreen compositions containing Δ5,7 steroidal dienes
JPS5832823A (en) * 1981-08-20 1983-02-25 Chugai Pharmaceut Co Ltd Cancer eliminating agent
JPS61282317A (en) * 1985-06-06 1986-12-12 Toyo Jozo Co Ltd Agent for promoting bone metabolism

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2301538A1 (en) * 1975-02-21 1976-09-17 Upjohn Co PROCESS FOR PREPARING 9B, 10A-CHOLESTA-5,7-DIENE-3B, 25-DIOL
US4749710A (en) * 1985-05-01 1988-06-07 Hoffmann-La Roche Inc. Immunosuppressive agents
DD285348A5 (en) * 1988-03-21 1990-12-12 Veb Jenapharm,Dd PROCESS FOR PREPARING 1S-25-DIHYDROXY CHOLECALCIFEROL

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 81, 1974, Columbus, Ohio, US; abstract no. 114422s, 'ANTIRACHITIC ACTIVITY OF LUMISTEROL' column 1 ; *
CHEMICAL ABSTRACTS, vol. 81, 1974, Columbus, Ohio, US; abstract no. 168147z, 'EFFECT OF LUMISTEROL3 ON CALCIUM ABSORPTION IN THE INTESTINES AND ON BONE TISSUE CALCIFICATION' page 442 ;column 1 ; *
CLINICAL RESEARCH vol. 30, no. 2, 1982, page 488A M.F. HOLICK 'ON THE ORIGIN AND FUNCTION OF PROVITAMIN D AS A UNIQUE NATURAL ULTRA-VIOLET SUNSCREEN' *
CLINICAL RESEARCH vol. 38, no. 2, April 1990, page 640A X.Q. TIAN ET AL. '1,25-DIHYDROXYVITAMIN D3: A NOVEL AGENT FOR WOUND HEALING' *
PATENT ABSTRACTS OF JAPAN vol. 7, no. 114 (C-166)(1259) 18 May 1983 & JP-A-58 032 823 ( CHUGAI SEIYAKU K.K. ) 25 February 1983 *
SCIENCE vol. 180, 1973, pages 1001 - 1003 M.F. HOLICK ET AL. 'ISOTACHYSTEROLS AND 25-HYDROXYISOTACHYSTEROLS' *
Section Ch, Week 8704, Derwent Publications Ltd., London, GB; Class B05, AN 87-025783 & JP-A-61 282317 (TOYO JOZO KK) 12 December 1986 *
See also references of WO9119479A1 *
THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM vol. 67, no. 2, 1988, pages 373 - 378 A.R. WEBB ET AL. 'INFLUENCE OF SEASON AND LATITUDE ON THE CUTANEOUS SYNTHESIS OF VITAMIN D3' *
THE JOURNAL OF INVESTIGATIVE DERMATOLOGY vol. 77, no. 1, 1981, pages 51 - 58 M.F. HOLICK 'THE CUTANEOUS PHOTOSYNTHESIS OF PREVITAMIN D3: A UNIQUE PHOTOENDOCRINE SYSTEM' *

Also Published As

Publication number Publication date
EP0536311A1 (en) 1993-04-14
WO1991019479A1 (en) 1991-12-26

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19930107

AK Designated contracting states

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Designated state(s): DE GB

A4 Supplementary search report drawn up and despatched

Effective date: 19930331

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17Q First examination report despatched

Effective date: 19941018

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19961001