IL96979A0 - Crystalline hydrochloride of new beta-lactam antibiotic and process therefor - Google Patents

Crystalline hydrochloride of new beta-lactam antibiotic and process therefor

Info

Publication number
IL96979A0
IL96979A0 IL96979A IL9697991A IL96979A0 IL 96979 A0 IL96979 A0 IL 96979A0 IL 96979 A IL96979 A IL 96979A IL 9697991 A IL9697991 A IL 9697991A IL 96979 A0 IL96979 A0 IL 96979A0
Authority
IL
Israel
Prior art keywords
lactam antibiotic
process therefor
crystalline hydrochloride
new beta
beta
Prior art date
Application number
IL96979A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL96979A0 publication Critical patent/IL96979A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL96979A 1990-01-26 1991-01-20 Crystalline hydrochloride of new beta-lactam antibiotic and process therefor IL96979A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47048690A 1990-01-26 1990-01-26

Publications (1)

Publication Number Publication Date
IL96979A0 true IL96979A0 (en) 1992-03-29

Family

ID=23867812

Family Applications (1)

Application Number Title Priority Date Filing Date
IL96979A IL96979A0 (en) 1990-01-26 1991-01-20 Crystalline hydrochloride of new beta-lactam antibiotic and process therefor

Country Status (19)

Country Link
EP (1) EP0439353B1 (zh)
JP (1) JPH04234880A (zh)
KR (1) KR910014378A (zh)
CN (1) CN1053611A (zh)
AU (1) AU631960B2 (zh)
CA (1) CA2034592C (zh)
DE (1) DE69118933T2 (zh)
ES (1) ES2087240T3 (zh)
FI (1) FI910365A (zh)
HU (1) HU208972B (zh)
IE (1) IE910251A1 (zh)
IL (1) IL96979A0 (zh)
MX (1) MX24247A (zh)
NO (1) NO910267L (zh)
NZ (1) NZ236868A (zh)
PT (1) PT96531A (zh)
RU (1) RU1825365C (zh)
YU (1) YU12191A (zh)
ZA (1) ZA91428B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
AU1234999A (en) * 1997-11-10 1999-05-31 Gist-Brocades B.V. Crystallization of beta-lactam compounds
AU2003283624A1 (en) * 2002-11-21 2004-06-15 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic

Also Published As

Publication number Publication date
AU631960B2 (en) 1992-12-10
CN1053611A (zh) 1991-08-07
HU208972B (en) 1994-02-28
EP0439353A1 (en) 1991-07-31
PT96531A (pt) 1991-10-15
FI910365A (fi) 1991-07-27
RU1825365C (ru) 1993-06-30
ZA91428B (en) 1992-09-30
YU12191A (sh) 1994-01-20
CA2034592C (en) 2001-06-05
IE910251A1 (en) 1991-07-31
EP0439353B1 (en) 1996-04-24
HUT57207A (en) 1991-11-28
MX24247A (es) 1993-11-01
NZ236868A (en) 1992-04-28
NO910267D0 (no) 1991-01-23
ES2087240T3 (es) 1996-07-16
JPH04234880A (ja) 1992-08-24
CA2034592A1 (en) 1991-07-27
FI910365A0 (fi) 1991-01-24
DE69118933T2 (de) 1996-10-02
AU6992391A (en) 1991-08-01
KR910014378A (ko) 1991-08-31
NO910267L (no) 1991-07-29
HU910263D0 (en) 1991-08-28
DE69118933D1 (de) 1996-05-30

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