IL96387A - Pour-on formulations containing antibiotics effective for the control of internal and external parasites of homothermic animals - Google Patents
Pour-on formulations containing antibiotics effective for the control of internal and external parasites of homothermic animalsInfo
- Publication number
- IL96387A IL96387A IL9638790A IL9638790A IL96387A IL 96387 A IL96387 A IL 96387A IL 9638790 A IL9638790 A IL 9638790A IL 9638790 A IL9638790 A IL 9638790A IL 96387 A IL96387 A IL 96387A
- Authority
- IL
- Israel
- Prior art keywords
- animals
- pour
- composition
- methyloxime
- farm
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 60
- 241001465754 Metazoa Species 0.000 title claims description 56
- 239000004540 pour-on Substances 0.000 title claims description 28
- 238000009472 formulation Methods 0.000 title description 31
- 239000003242 anti bacterial agent Substances 0.000 title description 3
- 244000045947 parasite Species 0.000 title description 3
- 229940088710 antibiotic agent Drugs 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims description 16
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 claims description 14
- 241000238421 Arthropoda Species 0.000 claims description 10
- 206010061217 Infestation Diseases 0.000 claims description 10
- 239000003849 aromatic solvent Substances 0.000 claims description 10
- OAYXUHPQHDHDDZ-UHFFFAOYSA-N 2-(2-butoxyethoxy)ethanol Chemical compound CCCCOCCOCCO OAYXUHPQHDHDDZ-UHFFFAOYSA-N 0.000 claims description 9
- 230000005484 gravity Effects 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 201000002266 mite infestation Diseases 0.000 claims description 8
- 244000000013 helminth Species 0.000 claims description 7
- 229920001083 polybutene Polymers 0.000 claims description 7
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims description 7
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 7
- 229920000053 polysorbate 80 Polymers 0.000 claims description 7
- 229940068968 polysorbate 80 Drugs 0.000 claims description 7
- USZDQUQLJBLEDN-UHFFFAOYSA-N 1-(1-tetradecoxypropan-2-yloxy)propan-2-yl propanoate Chemical compound CCCCCCCCCCCCCCOCC(C)OCC(C)OC(=O)CC USZDQUQLJBLEDN-UHFFFAOYSA-N 0.000 claims description 6
- 239000005660 Abamectin Substances 0.000 claims description 6
- 241000238631 Hexapoda Species 0.000 claims description 6
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 claims description 6
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 5
- 230000037396 body weight Effects 0.000 claims description 4
- 239000002480 mineral oil Substances 0.000 claims description 4
- 235000010446 mineral oil Nutrition 0.000 claims description 4
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 4
- 239000008158 vegetable oil Substances 0.000 claims description 4
- 229930194542 Keto Natural products 0.000 claims description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 3
- 125000000468 ketone group Chemical group 0.000 claims description 3
- 241001649230 Psoroptes ovis Species 0.000 claims description 2
- MBHCWRKFAXKMRT-UHFFFAOYSA-N propanoic acid;1-tetradecoxytetradecane Chemical compound CCC(O)=O.CCCCCCCCCCCCCCOCCCCCCCCCCCCCC MBHCWRKFAXKMRT-UHFFFAOYSA-N 0.000 claims description 2
- 108010034145 Helminth Proteins Proteins 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 description 9
- 239000003814 drug Substances 0.000 description 9
- 229940079593 drug Drugs 0.000 description 8
- 241000244206 Nematoda Species 0.000 description 7
- 241001494479 Pecora Species 0.000 description 7
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 241000283690 Bos taurus Species 0.000 description 5
- 229940059904 light mineral oil Drugs 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 244000309466 calf Species 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 241000243795 Ostertagia Species 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 2
- 241000238876 Acari Species 0.000 description 2
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 description 2
- 241000283898 Ovis Species 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- 229940124339 anthelmintic agent Drugs 0.000 description 2
- 239000000921 anthelmintic agent Substances 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 229960001614 levamisole Drugs 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 231100000344 non-irritating Toxicity 0.000 description 2
- 239000001593 sorbitan monooleate Substances 0.000 description 2
- 235000011069 sorbitan monooleate Nutrition 0.000 description 2
- 229940035049 sorbitan monooleate Drugs 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241001126268 Cooperia Species 0.000 description 1
- 241001147667 Dictyocaulus Species 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- PNVJTZOFSHSLTO-UHFFFAOYSA-N Fenthion Chemical compound COP(=S)(OC)OC1=CC=C(SC)C(C)=C1 PNVJTZOFSHSLTO-UHFFFAOYSA-N 0.000 description 1
- 241000243976 Haemonchus Species 0.000 description 1
- 241000243974 Haemonchus contortus Species 0.000 description 1
- 208000006968 Helminthiasis Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 241001137882 Nematodirus Species 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 241000282898 Sus scrofa Species 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 239000013011 aqueous formulation Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 239000013256 coordination polymer Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- -1 ester PPG-2-myristyl ether propionate Chemical class 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229960001952 metrifonate Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- YZBLFMPOMVTDJY-CBYMMZEQSA-N moxidectin Chemical compound O1[C@H](C(\C)=C\C(C)C)[C@@H](C)C(=N/OC)\C[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YZBLFMPOMVTDJY-CBYMMZEQSA-N 0.000 description 1
- 229960004816 moxidectin Drugs 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- NFACJZMKEDPNKN-UHFFFAOYSA-N trichlorfon Chemical compound COP(=O)(OC)C(O)C(Cl)(Cl)Cl NFACJZMKEDPNKN-UHFFFAOYSA-N 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 208000016261 weight loss Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL11186394A IL111863A (en) | 1990-11-19 | 1994-12-04 | POUR-ON FORMULATIONS CONTAINING AN LL-F28249 α-λ, A 23-OXO OR 23-IMINO DERIVATIVE OF AN LL-F28249 α-λ, A MILBEMYCIN MOLECULE OR AN AVERMECTIN MOLECULE WHICH ARE EFFECTIVE FOR THE CONTROL OF INTERNAL AND EXTERNAL PARASITES OF HOMOTHERMIC ANIMALS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45147289A | 1989-12-15 | 1989-12-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL96387A0 IL96387A0 (en) | 1991-08-16 |
| IL96387A true IL96387A (en) | 1995-06-29 |
Family
ID=23792355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9638790A IL96387A (en) | 1989-12-15 | 1990-11-19 | Pour-on formulations containing antibiotics effective for the control of internal and external parasites of homothermic animals |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0432494B1 (de) |
| JP (1) | JP2966530B2 (de) |
| KR (1) | KR100187949B1 (de) |
| AR (1) | AR247485A1 (de) |
| AT (1) | ATE148611T1 (de) |
| AU (1) | AU634325B2 (de) |
| BR (1) | BR9006387A (de) |
| CA (1) | CA2032233C (de) |
| DE (1) | DE69029899T2 (de) |
| DK (1) | DK0432494T3 (de) |
| ES (1) | ES2097127T3 (de) |
| GR (1) | GR3022496T3 (de) |
| HK (1) | HK1000003A1 (de) |
| HU (1) | HU206037B (de) |
| IE (1) | IE81105B1 (de) |
| IL (1) | IL96387A (de) |
| PT (1) | PT96177B (de) |
| ZA (1) | ZA9010087B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT697814E (pt) * | 1993-05-10 | 2003-11-28 | Merck & Co Inc | Formulacoes para verter que contem material polimerico glicois e gliceridos |
| US5602107A (en) * | 1993-05-10 | 1997-02-11 | Merck & Co., Inc. | Pour-on formulations consisting of gylcols, glycerides and avermectin compounds |
| PL174488B1 (pl) * | 1993-05-10 | 1998-08-31 | Merck & Co Inc | Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt |
| WO2010106325A2 (en) | 2009-03-18 | 2010-09-23 | Omnipharm Limited | Parasiticidal formulation |
| CN104193760B (zh) * | 2014-08-29 | 2016-11-30 | 宁夏泰瑞制药股份有限公司 | 一种利用奈马菌素发酵液提取奈马菌素粗品的方法 |
| GB2552952B (en) * | 2016-08-12 | 2020-03-04 | Norbrook Lab Ltd | Moxidectin topical liquid formulations |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2088212B (en) * | 1980-11-21 | 1985-12-04 | Wellcome Found | Pest control |
| GB2094626B (en) * | 1981-03-16 | 1985-02-20 | Young Robert Co Ltd | Insecticidal control of ectoparasites |
| EP0259779B1 (de) * | 1986-09-12 | 1994-08-10 | American Cyanamid Company | 23-Oxo(keto) und 23-Imino-Derivate von LL-F28249-Verbindungen |
| CA1306188C (en) * | 1987-10-05 | 1992-08-11 | Alan Robert Garden | Ectoparasiticidal pour-on formulation |
| GB8803836D0 (en) * | 1988-02-18 | 1988-03-16 | Glaxo Group Ltd | Compositions |
-
1990
- 1990-11-14 ES ES90121786T patent/ES2097127T3/es not_active Expired - Lifetime
- 1990-11-14 DE DE69029899T patent/DE69029899T2/de not_active Expired - Lifetime
- 1990-11-14 DK DK90121786.9T patent/DK0432494T3/da active
- 1990-11-14 AT AT90121786T patent/ATE148611T1/de not_active IP Right Cessation
- 1990-11-14 EP EP90121786A patent/EP0432494B1/de not_active Expired - Lifetime
- 1990-11-19 IL IL9638790A patent/IL96387A/en not_active IP Right Cessation
- 1990-12-12 JP JP2409882A patent/JP2966530B2/ja not_active Expired - Lifetime
- 1990-12-13 PT PT96177A patent/PT96177B/pt not_active IP Right Cessation
- 1990-12-13 CA CA002032233A patent/CA2032233C/en not_active Expired - Lifetime
- 1990-12-14 BR BR909006387A patent/BR9006387A/pt not_active Application Discontinuation
- 1990-12-14 ZA ZA9010087A patent/ZA9010087B/xx unknown
- 1990-12-14 KR KR1019900020619A patent/KR100187949B1/ko not_active Expired - Lifetime
- 1990-12-14 IE IE450990A patent/IE81105B1/en not_active IP Right Cessation
- 1990-12-14 AU AU68134/90A patent/AU634325B2/en not_active Expired
- 1990-12-14 AR AR90318633A patent/AR247485A1/es active
- 1990-12-14 HU HU908272A patent/HU206037B/hu unknown
-
1997
- 1997-02-06 GR GR960401480T patent/GR3022496T3/el unknown
- 1997-07-08 HK HK97101513A patent/HK1000003A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9006387A (pt) | 1991-09-24 |
| IL96387A0 (en) | 1991-08-16 |
| PT96177B (pt) | 1998-04-30 |
| GR3022496T3 (en) | 1997-05-31 |
| PT96177A (pt) | 1991-09-30 |
| JPH03258704A (ja) | 1991-11-19 |
| AU6813490A (en) | 1991-06-20 |
| JP2966530B2 (ja) | 1999-10-25 |
| HU206037B (en) | 1992-08-28 |
| IE904509A1 (en) | 1991-06-19 |
| EP0432494B1 (de) | 1997-02-05 |
| DK0432494T3 (da) | 1997-03-10 |
| AU634325B2 (en) | 1993-02-18 |
| ES2097127T3 (es) | 1997-04-01 |
| HU908272D0 (en) | 1991-06-28 |
| ATE148611T1 (de) | 1997-02-15 |
| IE81105B1 (en) | 2000-03-08 |
| KR910011269A (ko) | 1991-08-07 |
| AR247485A1 (es) | 1995-01-31 |
| ZA9010087B (en) | 1991-10-30 |
| CA2032233A1 (en) | 1991-06-16 |
| EP0432494A2 (de) | 1991-06-19 |
| HUT56264A (en) | 1991-08-28 |
| HK1000003A1 (en) | 1997-10-03 |
| CA2032233C (en) | 2001-04-24 |
| EP0432494A3 (en) | 1993-05-19 |
| DE69029899T2 (de) | 1997-06-05 |
| DE69029899D1 (de) | 1997-03-20 |
| KR100187949B1 (ko) | 1999-06-01 |
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| IL111863A (en) | POUR-ON FORMULATIONS CONTAINING AN LL-F28249 α-λ, A 23-OXO OR 23-IMINO DERIVATIVE OF AN LL-F28249 α-λ, A MILBEMYCIN MOLECULE OR AN AVERMECTIN MOLECULE WHICH ARE EFFECTIVE FOR THE CONTROL OF INTERNAL AND EXTERNAL PARASITES OF HOMOTHERMIC ANIMALS | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |