IL96009A0 - Pyrimidines - Google Patents
PyrimidinesInfo
- Publication number
- IL96009A0 IL96009A0 IL96009A IL9600990A IL96009A0 IL 96009 A0 IL96009 A0 IL 96009A0 IL 96009 A IL96009 A IL 96009A IL 9600990 A IL9600990 A IL 9600990A IL 96009 A0 IL96009 A0 IL 96009A0
- Authority
- IL
- Israel
- Prior art keywords
- pyrimidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH379989 | 1989-10-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL96009A0 true IL96009A0 (en) | 1991-07-18 |
Family
ID=4263704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL96009A IL96009A0 (en) | 1989-10-19 | 1990-10-15 | Pyrimidines |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0424317A3 (ja) |
JP (1) | JPH03133964A (ja) |
KR (1) | KR910007889A (ja) |
AU (1) | AU638496B2 (ja) |
CA (1) | CA2027839A1 (ja) |
FI (1) | FI93957C (ja) |
HU (1) | HUT55383A (ja) |
IE (1) | IE903749A1 (ja) |
IL (1) | IL96009A0 (ja) |
MX (1) | MX22877A (ja) |
NO (1) | NO176758C (ja) |
NZ (1) | NZ235726A (ja) |
PT (1) | PT95626A (ja) |
ZA (1) | ZA908344B (ja) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5324729A (en) * | 1990-03-30 | 1994-06-28 | Merck & Co., Inc. | Substituted pyrimidines, pyrimidinones and pyridopyrimidines |
EP0522038A4 (en) * | 1990-03-30 | 1993-05-26 | Merck & Co. Inc. | Substituted pyrimidines, pyrimidinones and pyridopyrimidines |
NZ238624A (en) * | 1990-06-19 | 1994-08-26 | Meiji Seika Co | Pyridine derivatives, compositions, preparations and use thereof |
IL99246A0 (en) * | 1990-09-10 | 1992-07-15 | Abbott Lab | Angiotensin ii receptor antagonists and pharmaceutical compositions containing them |
US5250548A (en) * | 1990-09-10 | 1993-10-05 | Abbott Laboratories | Angiotensin II receptor antagonists |
FR2672892B1 (fr) * | 1991-02-20 | 1994-01-14 | Synthelabo | Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique. |
US5472967A (en) * | 1991-02-20 | 1995-12-05 | Synthelabo | 4-pyrimidinone derivatives their preparation and their application in therapy |
DE4110019C2 (de) * | 1991-03-27 | 2000-04-13 | Merck Patent Gmbh | Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
IL101860A0 (en) * | 1991-05-31 | 1992-12-30 | Ici Plc | Heterocyclic derivatives |
IT1250749B (it) * | 1991-08-02 | 1995-04-21 | Luso Farmaco Inst | Composti eterociclici ad attivita' a ii antagonista |
US5234936A (en) * | 1991-10-24 | 1993-08-10 | American Home Products Corporation | Pyrimidocycloalkanes as a ii antagonists |
US5256781A (en) * | 1991-10-24 | 1993-10-26 | American Home Products Corporation | Substituted quinazolines as angiotensin II antagonists |
US5236925A (en) * | 1991-10-24 | 1993-08-17 | American Home Products Corporation | Fused pyrimidines as angiotensin II antagonists |
DE4221583A1 (de) | 1991-11-12 | 1993-05-13 | Bayer Ag | Substituierte biphenylpyridone |
GB9125842D0 (en) * | 1991-12-04 | 1992-02-05 | Ici Plc | Heterocyclic derivatives |
US5225408A (en) * | 1991-12-20 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Biphenyl oxadiazinone angiotensin II inhibitors |
IL104756A0 (en) * | 1992-02-17 | 1993-06-10 | Ciba Geigy Ag | Composition for the treatment of glaucoma |
US5378704A (en) * | 1992-04-15 | 1995-01-03 | E. R. Squibb & Sons, Inc. | Non-peptidic angiotensin-II-receptor-antagonists |
US5236916A (en) * | 1992-05-26 | 1993-08-17 | E. R. Squibb & Sons, Inc. | Oxadiazinone substituted indole and benzimidazole derivatives |
TW348175B (en) * | 1993-01-06 | 1998-12-21 | Hoechst Ag | Process for the preparation of biphenyl derivatives |
AU1522400A (en) | 1998-11-12 | 2000-05-29 | Elan Pharmaceuticals, Inc. | Substituted pyrimidine compositions and methods of use |
SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
JP4880473B2 (ja) | 2004-10-08 | 2012-02-22 | 壽製薬株式会社 | ホスホン酸誘導体及び血中の高リン酸が関与する疾患の治療剤 |
US8080571B2 (en) * | 2005-04-12 | 2011-12-20 | Vicore Pharma Ab | Tricyclic angiotensin II agonists |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US20120322819A1 (en) * | 2010-02-25 | 2012-12-20 | Kowa Company, Ltd. | Compound containing a novel 4-alkoxypyrimidine structure and medicine containing same |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法 |
CN116134025A (zh) * | 2020-09-17 | 2023-05-16 | 浙江海正药业股份有限公司 | 酰胺膦氧类衍生物及其制备方法和用途 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
-
1990
- 1990-10-10 EP EP19900810777 patent/EP0424317A3/de not_active Withdrawn
- 1990-10-15 IL IL96009A patent/IL96009A0/xx unknown
- 1990-10-16 AU AU64680/90A patent/AU638496B2/en not_active Ceased
- 1990-10-17 MX MX2287790A patent/MX22877A/es unknown
- 1990-10-17 FI FI905124A patent/FI93957C/fi not_active IP Right Cessation
- 1990-10-17 CA CA002027839A patent/CA2027839A1/en not_active Abandoned
- 1990-10-17 NZ NZ235726A patent/NZ235726A/xx unknown
- 1990-10-18 HU HU906501A patent/HUT55383A/hu unknown
- 1990-10-18 ZA ZA908344A patent/ZA908344B/xx unknown
- 1990-10-18 IE IE374990A patent/IE903749A1/en unknown
- 1990-10-18 PT PT95626A patent/PT95626A/pt not_active Application Discontinuation
- 1990-10-18 NO NO904511A patent/NO176758C/no unknown
- 1990-10-18 KR KR1019900016590A patent/KR910007889A/ko not_active Application Discontinuation
- 1990-10-19 JP JP2279461A patent/JPH03133964A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA908344B (en) | 1991-06-26 |
EP0424317A3 (en) | 1991-09-25 |
HUT55383A (en) | 1991-05-28 |
FI93957C (fi) | 1995-06-26 |
PT95626A (pt) | 1991-09-13 |
CA2027839A1 (en) | 1991-04-20 |
NO904511D0 (no) | 1990-10-18 |
IE903749A1 (en) | 1991-04-24 |
NO904511L (no) | 1991-04-22 |
NZ235726A (en) | 1993-09-27 |
MX22877A (es) | 1993-12-01 |
AU6468090A (en) | 1991-04-26 |
FI905124A0 (fi) | 1990-10-17 |
EP0424317A2 (de) | 1991-04-24 |
JPH03133964A (ja) | 1991-06-07 |
NO176758B (no) | 1995-02-13 |
NO176758C (no) | 1995-05-24 |
KR910007889A (ko) | 1991-05-30 |
AU638496B2 (en) | 1993-07-01 |
FI93957B (fi) | 1995-03-15 |
HU906501D0 (en) | 1991-04-29 |
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