IL95884A - Glucosides of the alkoxymethylidene epipodophilotoxin and pharmaceutical preparations containing them - Google Patents

Glucosides of the alkoxymethylidene epipodophilotoxin and pharmaceutical preparations containing them

Info

Publication number
IL95884A
IL95884A IL9588490A IL9588490A IL95884A IL 95884 A IL95884 A IL 95884A IL 9588490 A IL9588490 A IL 9588490A IL 9588490 A IL9588490 A IL 9588490A IL 95884 A IL95884 A IL 95884A
Authority
IL
Israel
Prior art keywords
hydrogen
compounds
compound
alkoxy
formula
Prior art date
Application number
IL9588490A
Other languages
English (en)
Hebrew (he)
Other versions
IL95884A0 (en
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL95884A0 publication Critical patent/IL95884A0/xx
Publication of IL95884A publication Critical patent/IL95884A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL9588490A 1989-11-20 1990-10-02 Glucosides of the alkoxymethylidene epipodophilotoxin and pharmaceutical preparations containing them IL95884A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/438,829 US5034380A (en) 1989-11-20 1989-11-20 Alkoxymethylidene epipodophyllotoxin glucosides

Publications (2)

Publication Number Publication Date
IL95884A0 IL95884A0 (en) 1991-07-18
IL95884A true IL95884A (en) 1994-10-21

Family

ID=23742200

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9588490A IL95884A (en) 1989-11-20 1990-10-02 Glucosides of the alkoxymethylidene epipodophilotoxin and pharmaceutical preparations containing them

Country Status (15)

Country Link
US (1) US5034380A (pt)
EP (1) EP0433678A1 (pt)
JP (1) JPH0686476B2 (pt)
KR (1) KR930007382B1 (pt)
AU (1) AU614698B2 (pt)
CA (1) CA2029748A1 (pt)
FI (1) FI905685A (pt)
HU (1) HU208019B (pt)
IE (1) IE904162A1 (pt)
IL (1) IL95884A (pt)
NO (1) NO174204C (pt)
NZ (1) NZ236106A (pt)
PT (1) PT95931A (pt)
YU (1) YU220790A (pt)
ZA (1) ZA909252B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW260671B (pt) * 1991-04-29 1995-10-21 Bristol Myers Squibb Co
US5458299A (en) * 1993-11-17 1995-10-17 Collins; Kenneth Aircraft deicing apparatus
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171314A (fr) * 1955-05-13 1959-01-23 Sandoz Ag Produits de condensation de glucosides avec des composés carbonyliques et leur préparation
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフイロトキシン誘導体
US4916217A (en) * 1987-01-08 1990-04-10 Bristol-Myers Company Phosphorus containing derivatives of epipodophyllotoxin
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4912204A (en) * 1988-09-06 1990-03-27 Bristol-Myers Company Fluoro-substituted epipodophyllotoxin glucosides
DE3913326A1 (de) * 1989-04-22 1990-11-08 Behringwerke Ag Verfahren zur herstellung von etoposiden
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
JPH087254B2 (ja) * 1989-08-07 1996-01-29 富士通株式会社 半導体集積回路装置

Also Published As

Publication number Publication date
JPH0686476B2 (ja) 1994-11-02
NO904967L (no) 1991-05-21
ZA909252B (en) 1991-09-25
YU220790A (sh) 1992-09-07
KR910009720A (ko) 1991-06-28
NO174204C (no) 1994-04-06
NO174204B (no) 1993-12-20
FI905685A (fi) 1991-05-21
CA2029748A1 (en) 1991-05-21
JPH03170494A (ja) 1991-07-24
PT95931A (pt) 1991-09-13
IE904162A1 (en) 1991-05-22
HU208019B (en) 1993-07-28
HUT55406A (en) 1991-05-28
FI905685A0 (fi) 1990-11-16
KR930007382B1 (ko) 1993-08-09
AU6671190A (en) 1991-05-23
NO904967D0 (no) 1990-11-16
US5034380A (en) 1991-07-23
IL95884A0 (en) 1991-07-18
NZ236106A (en) 1991-11-26
EP0433678A1 (en) 1991-06-26
AU614698B2 (en) 1991-09-05

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Legal Events

Date Code Title Description
RH Patent void