IL95283A0 - Human thrombomodulin derivatives - Google Patents

Human thrombomodulin derivatives

Info

Publication number
IL95283A0
IL95283A0 IL95283A IL9528390A IL95283A0 IL 95283 A0 IL95283 A0 IL 95283A0 IL 95283 A IL95283 A IL 95283A IL 9528390 A IL9528390 A IL 9528390A IL 95283 A0 IL95283 A0 IL 95283A0
Authority
IL
Israel
Prior art keywords
human thrombomodulin
thrombomodulin derivatives
derivatives
human
thrombomodulin
Prior art date
Application number
IL95283A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL95283A0 publication Critical patent/IL95283A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL95283A 1989-08-11 1990-08-05 Human thrombomodulin derivatives IL95283A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39361789A 1989-08-11 1989-08-11
US47487090A 1990-02-05 1990-02-05

Publications (1)

Publication Number Publication Date
IL95283A0 true IL95283A0 (en) 1991-06-30

Family

ID=27014375

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95283A IL95283A0 (en) 1989-08-11 1990-08-05 Human thrombomodulin derivatives

Country Status (7)

Country Link
EP (1) EP0412841A1 (xx)
JP (1) JPH03133380A (xx)
AU (1) AU6085890A (xx)
CA (1) CA2022713A1 (xx)
HU (1) HUT56876A (xx)
IE (1) IE902907A1 (xx)
IL (1) IL95283A0 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04505554A (ja) * 1989-02-17 1992-10-01 コドン 可溶性トロンボモジュリン類似体
EP0641215B1 (en) * 1992-02-05 2004-04-21 Paion GmbH Protease-resistant thrombomodulin analogs
JPH05310787A (ja) * 1992-05-01 1993-11-22 Asahi Chem Ind Co Ltd 新規なポリペプチド
US5585095A (en) * 1993-09-14 1996-12-17 Regents Of The University Of Minnesota Method to enhance thrombomodulin APC generation using cationic proteins
US5639625A (en) * 1994-09-26 1997-06-17 Oklahoma Medical Research Foundation Method for detecting antibodies to thrombomodulin in patients
DE69535317T2 (de) * 1994-10-18 2007-06-21 Dendreon Corp., Seattle Aus nematoden extrahierte serinprotease-inhibitoren und die koagulation hemmende proteine
WO2002066669A1 (en) * 2001-02-23 2002-08-29 Biovitrum Ab Method for purification of soluble ssao
DK1948216T3 (da) * 2005-10-13 2011-06-06 Lilly Co Eli Behandling af akut nyresvigt med opløselig thrombomodulin
KR20090051777A (ko) 2006-10-06 2009-05-22 아사히 가세이 파마 가부시키가이샤 파종성 혈관내 혈액 응고 증후군의 치료 및/또는 개선제
US8076298B2 (en) 2006-12-12 2011-12-13 Eli Lilly And Company Treating acute renal failure with soluble thrombomodulin variants
CA2681294C (en) 2007-03-23 2014-05-06 Asahi Kasei Pharma Corporation Method for producing high-purity soluble thrombomodulin
NZ602852A (en) 2010-04-30 2014-03-28 Asahi Kasei Pharma Corp Highly-purified soluble thrombomodulin and method for producing same
RU2580756C2 (ru) 2011-11-15 2016-04-10 Асахи Касеи Фарма Корпорейшн Лекарственное средство для терапевтического лечения и/или улучшения состояния при сепсисе
WO2014020183A1 (de) * 2012-08-03 2014-02-06 Ici Immunochemical Intelligence Gmbh In-vitro-assay zur diagnose von störungen der hämostase
EP3871684B1 (en) 2018-10-22 2024-06-26 Asahi Kasei Pharma Corporation Drug for treating and/or improving septicemia associated with coagulation abnormality

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE180496T1 (de) * 1987-01-08 1999-06-15 Asahi Chemical Ind Peptid zur beschleunigung der wirkung des proteins-c mit thrombin
DK299087D0 (da) * 1987-06-12 1987-06-12 Novo Industri As Proteins and derivatives thereof

Also Published As

Publication number Publication date
HUT56876A (en) 1991-10-28
EP0412841A1 (en) 1991-02-13
JPH03133380A (ja) 1991-06-06
CA2022713A1 (en) 1991-02-12
HU904924D0 (en) 1991-01-28
IE902907A1 (en) 1991-02-27
AU6085890A (en) 1991-02-14

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