IL95283A0 - Human thrombomodulin derivatives - Google Patents

Human thrombomodulin derivatives

Info

Publication number
IL95283A0
IL95283A0 IL95283A IL9528390A IL95283A0 IL 95283 A0 IL95283 A0 IL 95283A0 IL 95283 A IL95283 A IL 95283A IL 9528390 A IL9528390 A IL 9528390A IL 95283 A0 IL95283 A0 IL 95283A0
Authority
IL
Israel
Prior art keywords
human thrombomodulin
thrombomodulin derivatives
derivatives
human
thrombomodulin
Prior art date
Application number
IL95283A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL95283A0 publication Critical patent/IL95283A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL95283A 1989-08-11 1990-08-05 Human thrombomodulin derivatives IL95283A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39361789A 1989-08-11 1989-08-11
US47487090A 1990-02-05 1990-02-05

Publications (1)

Publication Number Publication Date
IL95283A0 true IL95283A0 (en) 1991-06-30

Family

ID=27014375

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95283A IL95283A0 (en) 1989-08-11 1990-08-05 Human thrombomodulin derivatives

Country Status (7)

Country Link
EP (1) EP0412841A1 (fr)
JP (1) JPH03133380A (fr)
AU (1) AU6085890A (fr)
CA (1) CA2022713A1 (fr)
HU (1) HUT56876A (fr)
IE (1) IE902907A1 (fr)
IL (1) IL95283A0 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0458903A4 (en) * 1989-02-17 1992-06-17 Codon Soluble analogs of thrombomodulin
PT641215E (pt) * 1992-02-05 2004-09-30 Paion Gmbh Analogos de trombomodulina resistentes a proteases
JPH05310787A (ja) * 1992-05-01 1993-11-22 Asahi Chem Ind Co Ltd 新規なポリペプチド
US5585095A (en) * 1993-09-14 1996-12-17 Regents Of The University Of Minnesota Method to enhance thrombomodulin APC generation using cationic proteins
US5639625A (en) * 1994-09-26 1997-06-17 Oklahoma Medical Research Foundation Method for detecting antibodies to thrombomodulin in patients
ATE346928T1 (de) * 1994-10-18 2006-12-15 Dendreon Corp Aus nematoden extrahierte serinprotease- inhibitoren und die koagulation hemmende proteine
WO2002066669A1 (fr) * 2001-02-23 2002-08-29 Biovitrum Ab Procede de purification de ssao soluble
ATE503489T1 (de) * 2005-10-13 2011-04-15 Lilly Co Eli Behandlung von akutem nierenversagen mit löslichem thrombomodulin
WO2008044631A1 (fr) 2006-10-06 2008-04-17 Asahi Kasei Pharma Corporation Agent thérapeutique et/ou améliorant pour la coagulation intravasculaire disséminée
CA2671863C (fr) 2006-12-12 2015-07-21 Eli Lilly And Company Procede de traitement de sujets atteints d'une insuffisance renale aigue au moyen de variantes de la thrombomoduline
SG184699A1 (en) 2007-03-23 2012-10-30 Asahi Kasei Pharma Corp Method for producing high-purity soluble thrombomodulin
EP2565269B1 (fr) 2010-04-30 2016-11-16 Asahi Kasei Pharma Corporation Méthode de production de la thrombomoduline soluble de pureté élevée
CN103974710B (zh) 2011-11-15 2016-07-06 旭化成制药株式会社 用于败血症的治疗和/或改善的药物
WO2014020183A1 (fr) * 2012-08-03 2014-02-06 Ici Immunochemical Intelligence Gmbh Essai de diagnostic in vitro de troubles de l'hémostase
EP3871684B1 (fr) 2018-10-22 2024-06-26 Asahi Kasei Pharma Corporation Médicament permettant de traiter et/ou d'atténuer la septicémie associée à une anomalie de coagulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856335T2 (de) * 1987-01-08 2000-01-27 Asahi Chemical Ind Peptid zur beschleunigung der wirkung des proteins-c mit thrombin
DK299087D0 (da) * 1987-06-12 1987-06-12 Novo Industri As Proteins and derivatives thereof

Also Published As

Publication number Publication date
EP0412841A1 (fr) 1991-02-13
AU6085890A (en) 1991-02-14
CA2022713A1 (fr) 1991-02-12
JPH03133380A (ja) 1991-06-06
HUT56876A (en) 1991-10-28
HU904924D0 (en) 1991-01-28
IE902907A1 (en) 1991-02-27

Similar Documents

Publication Publication Date Title
IL94047A0 (en) 3-substituted-2-oxindole derivatives
EP0430709A3 (en) Benzthiophen derivatives
IL95283A0 (en) Human thrombomodulin derivatives
EP0431421A3 (en) Heteroarylsubstituted pyridinylpyrimidin derivatives
HK95192A (en) Thieno-triazolo-diazepine derivatives
GB2231330B (en) Thieno-triazolo-diazepine derivatives
EP0431424A3 (en) Pyridinylpyrimidin derivatives
ZA903984B (en) Phosphonomethylthioalkoxypyrine derivatives
IL94987A0 (en) Croman derivatives
GB2229724B (en) Thieno-triazolo-diazepine derivatives
EP0479951A4 (en) Bis-acyloxymethyl derivatives
GB9015831D0 (en) Dihydropyrimidothiazine derivatives
EP0411636A3 (en) Piperidylthiocarbapenem derivatives
GB8918275D0 (en) Fluoro-chloro-benzene derivatives
EP0438686A3 (en) Triazolylmethyl-cyclopropyl derivatives
GB2238310B (en) Selenophen derivatives
GB9017950D0 (en) Fluoro-chloro-benzene derivatives
GB8916635D0 (en) Cardanolactam derivatives
IE893935L (en) Benzopyranylpyrrolinone derivatives
ZA90203B (en) Cyclohexaneacetamide derivatives
ZA906023B (en) 1-phenylalkyl-3-phenylurea derivatives
GB8913442D0 (en) Fluoro-chloro-benzene derivatives
ZA905417B (en) Thienodiazepine derivatives
IE891748L (en) Cyclopentane-purine derivatives
GB8928445D0 (en) Benzofuranyl-imidazole derivatives