IL92271A0 - Hydrates of beta-lactam antibiotic - Google Patents

Hydrates of beta-lactam antibiotic

Info

Publication number
IL92271A0
IL92271A0 IL92271A IL9227189A IL92271A0 IL 92271 A0 IL92271 A0 IL 92271A0 IL 92271 A IL92271 A IL 92271A IL 9227189 A IL9227189 A IL 9227189A IL 92271 A0 IL92271 A0 IL 92271A0
Authority
IL
Israel
Prior art keywords
hydrates
beta
lactam antibiotic
lactam
antibiotic
Prior art date
Application number
IL92271A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL92271A0 publication Critical patent/IL92271A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
IL92271A 1988-11-14 1989-11-10 Hydrates of beta-lactam antibiotic IL92271A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27179488A 1988-11-14 1988-11-14

Publications (1)

Publication Number Publication Date
IL92271A0 true IL92271A0 (en) 1990-07-26

Family

ID=23037114

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92271A IL92271A0 (en) 1988-11-14 1989-11-10 Hydrates of beta-lactam antibiotic

Country Status (13)

Country Link
EP (1) EP0369686A1 (pt)
JP (1) JPH02178281A (pt)
KR (1) KR900007840A (pt)
CN (1) CN1042712A (pt)
AU (1) AU620659B2 (pt)
CA (1) CA2002596A1 (pt)
DK (1) DK563789A (pt)
HU (1) HU205113B (pt)
IL (1) IL92271A0 (pt)
NZ (1) NZ231368A (pt)
PT (1) PT92275A (pt)
SU (1) SU1757468A3 (pt)
ZA (1) ZA898611B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5399686A (en) * 1993-06-04 1995-03-21 Eli Lilly And Company Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5374719A (en) * 1993-06-04 1994-12-20 Eli Lilly And Company Process for converting loracarbef dihydrate to loracarbef monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5412094A (en) * 1993-06-28 1995-05-02 Eli Lilly And Company Bicyclic beta-lactam/paraben complexes
US5580977A (en) * 1995-03-01 1996-12-03 Eli Lilly And Company Process for preparing loracarbef monohydrate
US6001996A (en) * 1995-05-11 1999-12-14 Eli Lilly And Company Complexes of cephalosporins and carbacephalosporins with parabens
ZA978515B (en) * 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
WO2004046142A1 (en) * 2002-11-21 2004-06-03 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef
JP5137228B2 (ja) 2003-03-07 2013-02-06 メルク・シャープ・アンド・ドーム・コーポレーション 高コレステロール血症の処置のための置換アゼチジノン化合物、置換アゼチジノン処方物およびそれらの使用
EP1601669B1 (en) 2003-03-07 2008-12-24 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
MY104063A (en) * 1987-10-06 1993-11-30 Lilly Co Eli Crystalline (beta)-lactam hydrate
IL89150A0 (en) * 1988-02-05 1989-09-10 Lilly Co Eli Crystalline beta-lactam solvate
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic

Also Published As

Publication number Publication date
CN1042712A (zh) 1990-06-06
DK563789D0 (da) 1989-11-10
EP0369686A1 (en) 1990-05-23
AU620659B2 (en) 1992-02-20
JPH02178281A (ja) 1990-07-11
HUT52508A (en) 1990-07-28
CA2002596A1 (en) 1990-05-14
SU1757468A3 (ru) 1992-08-23
HU205113B (en) 1992-03-30
AU4457089A (en) 1990-05-31
DK563789A (da) 1990-05-15
PT92275A (pt) 1990-05-31
NZ231368A (en) 1990-12-21
KR900007840A (ko) 1990-06-02
ZA898611B (en) 1991-07-31

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