DK563789A - Hydrater af et beta-lactam-antibiotikum og fremgangsmaade til fremstilling af saadanne hydrater - Google Patents
Hydrater af et beta-lactam-antibiotikum og fremgangsmaade til fremstilling af saadanne hydraterInfo
- Publication number
- DK563789A DK563789A DK563789A DK563789A DK563789A DK 563789 A DK563789 A DK 563789A DK 563789 A DK563789 A DK 563789A DK 563789 A DK563789 A DK 563789A DK 563789 A DK563789 A DK 563789A
- Authority
- DK
- Denmark
- Prior art keywords
- hydrates
- beta
- procedure
- preparation
- lactam antibiotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27179488A | 1988-11-14 | 1988-11-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK563789D0 DK563789D0 (da) | 1989-11-10 |
| DK563789A true DK563789A (da) | 1990-05-15 |
Family
ID=23037114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK563789A DK563789A (da) | 1988-11-14 | 1989-11-10 | Hydrater af et beta-lactam-antibiotikum og fremgangsmaade til fremstilling af saadanne hydrater |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0369686A1 (da) |
| JP (1) | JPH02178281A (da) |
| KR (1) | KR900007840A (da) |
| CN (1) | CN1042712A (da) |
| AU (1) | AU620659B2 (da) |
| CA (1) | CA2002596A1 (da) |
| DK (1) | DK563789A (da) |
| HU (1) | HU205113B (da) |
| IL (1) | IL92271A0 (da) |
| NZ (1) | NZ231368A (da) |
| PT (1) | PT92275A (da) |
| SU (1) | SU1757468A3 (da) |
| ZA (1) | ZA898611B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
| CA2034592C (en) * | 1990-01-26 | 2001-06-05 | Ralph R. Pfeiffer | Crystalline hydrochloride of new beta-lactam antibiotic and process therefor |
| US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
| US5374719A (en) * | 1993-06-04 | 1994-12-20 | Eli Lilly And Company | Process for converting loracarbef dihydrate to loracarbef monohydrate |
| US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
| US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
| US5412094A (en) * | 1993-06-28 | 1995-05-02 | Eli Lilly And Company | Bicyclic beta-lactam/paraben complexes |
| US5580977A (en) * | 1995-03-01 | 1996-12-03 | Eli Lilly And Company | Process for preparing loracarbef monohydrate |
| US6001996A (en) * | 1995-05-11 | 1999-12-14 | Eli Lilly And Company | Complexes of cephalosporins and carbacephalosporins with parabens |
| ZA978515B (en) * | 1996-09-23 | 1999-03-23 | Lilly Co Eli | Intermediates and process for preparing olanzapine |
| WO2004046142A1 (en) * | 2002-11-21 | 2004-06-03 | Ranbaxy Laboratories Limited | Monohydrate solvates of loracarbef |
| ATE406364T1 (de) | 2003-03-07 | 2008-09-15 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| ES2318274T3 (es) | 2003-03-07 | 2009-05-01 | Schering Corporation | Compuestos de azetidinona sustituida, formulaciones y uso de los mismos para el tratamiento de hipercolesterolemia. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
| DD273634A5 (de) * | 1987-10-06 | 1989-11-22 | ����@�����@�����@����k�� | Verfahren zur herstellung eines kristallinen monohydrats eines 1-carbacephalosporins |
| ZA89829B (en) * | 1988-02-05 | 1990-10-31 | Lilly Co Eli | Crystalline b-lactam solvate |
| CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
-
1989
- 1989-11-09 CA CA002002596A patent/CA2002596A1/en not_active Abandoned
- 1989-11-10 AU AU44570/89A patent/AU620659B2/en not_active Ceased
- 1989-11-10 DK DK563789A patent/DK563789A/da not_active Application Discontinuation
- 1989-11-10 EP EP89311636A patent/EP0369686A1/en not_active Withdrawn
- 1989-11-10 PT PT92275A patent/PT92275A/pt not_active Application Discontinuation
- 1989-11-10 IL IL92271A patent/IL92271A0/xx unknown
- 1989-11-10 ZA ZA898611A patent/ZA898611B/xx unknown
- 1989-11-11 KR KR1019890016365A patent/KR900007840A/ko not_active Application Discontinuation
- 1989-11-13 SU SU894742389A patent/SU1757468A3/ru active
- 1989-11-13 JP JP1294753A patent/JPH02178281A/ja active Pending
- 1989-11-13 NZ NZ231368A patent/NZ231368A/en unknown
- 1989-11-13 HU HU895882A patent/HU205113B/hu not_active IP Right Cessation
- 1989-11-13 CN CN89108712A patent/CN1042712A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU620659B2 (en) | 1992-02-20 |
| ZA898611B (en) | 1991-07-31 |
| HU205113B (en) | 1992-03-30 |
| JPH02178281A (ja) | 1990-07-11 |
| PT92275A (pt) | 1990-05-31 |
| KR900007840A (ko) | 1990-06-02 |
| SU1757468A3 (ru) | 1992-08-23 |
| AU4457089A (en) | 1990-05-31 |
| DK563789D0 (da) | 1989-11-10 |
| CN1042712A (zh) | 1990-06-06 |
| IL92271A0 (en) | 1990-07-26 |
| NZ231368A (en) | 1990-12-21 |
| EP0369686A1 (en) | 1990-05-23 |
| HUT52508A (en) | 1990-07-28 |
| CA2002596A1 (en) | 1990-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |