IL92079A - Datastoxyclosphorophorin C synthase and its preparation - Google Patents
Datastoxyclosphorophorin C synthase and its preparationInfo
- Publication number
- IL92079A IL92079A IL9207989A IL9207989A IL92079A IL 92079 A IL92079 A IL 92079A IL 9207989 A IL9207989 A IL 9207989A IL 9207989 A IL9207989 A IL 9207989A IL 92079 A IL92079 A IL 92079A
- Authority
- IL
- Israel
- Prior art keywords
- buffer
- enzyme
- activity
- synthase
- dna
- Prior art date
Links
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- 229940056360 penicillin g Drugs 0.000 description 1
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- BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/261,437 US5082772A (en) | 1988-10-24 | 1988-10-24 | Process for preparing deacetylcephalosporin c |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL92079A true IL92079A (en) | 1994-08-26 |
Family
ID=22993294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9207989A IL92079A (en) | 1988-10-24 | 1989-10-22 | Datastoxyclosphorophorin C synthase and its preparation |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5082772A (de) |
| EP (1) | EP0366354B1 (de) |
| JP (1) | JPH02242675A (de) |
| DE (1) | DE68925338T2 (de) |
| DK (1) | DK521489A (de) |
| ES (1) | ES2082787T3 (de) |
| GR (1) | GR3018596T3 (de) |
| IL (1) | IL92079A (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0233715B1 (de) * | 1986-01-31 | 1994-05-25 | BEECHAM GROUP plc | Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen |
| US6709859B1 (en) | 1986-01-31 | 2004-03-23 | Beecham Group P.L.C. | Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression |
| HU219370B (en) * | 1991-10-15 | 2001-03-28 | Gist Brocades Bv | Novel bioprocesses for preparing 7-aca and 7-adac |
| WO1995004148A1 (en) * | 1993-07-30 | 1995-02-09 | Gist-Brocades B.V. | Process for the efficient production of 7-adca via 2-(carboxyethylthio)acetyl-7-adca and 3-(carboxymethylthio)propionyl-7-adca |
| WO1995004149A1 (en) * | 1993-07-30 | 1995-02-09 | Gist-Brocades B.V. | Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca |
| RU2139349C1 (ru) * | 1993-07-30 | 1999-10-10 | Гист-Брокейдс Б.В. | Способ эффективного производства 7-адцк через 2-(карбоксиэтилтио) ацетил-7-адцк и 3-(карбоксиметилтио)пропионил-7-адцк |
| US5571910A (en) * | 1994-12-09 | 1996-11-05 | Schering Corporation | Process for the preparation of intermediates useful in the synthesis of cephalosporins |
| US5731165A (en) * | 1995-06-02 | 1998-03-24 | Gist-Brocades, B.V. | Process for the production of 7-ADCA via expandase activity on penicillin G |
| AU1097297A (en) * | 1995-11-27 | 1997-06-19 | Gist-Brocades B.V. | Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin |
| WO1998002551A2 (en) * | 1996-07-16 | 1998-01-22 | Gist-Brocades B.V. | Process for the production of adipoyl cephalosporins |
| JP2002500015A (ja) * | 1997-12-24 | 2002-01-08 | アイシス イノヴェイション リミテッド | 改変型デアセトキシセファロスポリンｃシンターゼ（ｄａｏｃｓ）およびｘ線構造 |
| US6383773B2 (en) * | 1998-04-23 | 2002-05-07 | Massachusetts Institute Of Technology | Penicillin conversion |
| PL344863A1 (en) | 1998-05-19 | 2001-11-19 | Dsm Nv | Improved in vivo |
| DE10051628B4 (de) * | 2000-10-18 | 2007-06-06 | Fresenius Hemocare Beteiligungs Gmbh | Einzelsträngiges Oligonukleotid und dessen Verwendung |
| US6699699B2 (en) | 2002-03-26 | 2004-03-02 | Synmax Biochemical Co., Ltd. | Mutated penicillin expandases |
| CN113234093A (zh) * | 2021-04-13 | 2021-08-10 | 伊犁川宁生物技术股份有限公司 | 一种3-去乙酰氧基头孢菌素c钠盐及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3847742A (en) * | 1972-04-26 | 1974-11-12 | C Higgens | Process for deacetoxycephalosporin c |
| JPS5539735A (en) * | 1978-09-11 | 1980-03-19 | Takeda Chem Ind Ltd | Preparation of deacetyl cephalosporin c |
| US4414328A (en) * | 1980-07-21 | 1983-11-08 | Fujisawa Pharmaceutical Co., Ltd. | Process for the preparation of deacetylcephalosporin C |
| US4510246A (en) * | 1982-08-23 | 1985-04-09 | Queen's University At Kingston | Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins |
| US4693977A (en) * | 1982-08-23 | 1987-09-15 | Queen's University At Kingston | Enzyme immobilization for producing cephalosporin antibiotics |
| US4536476A (en) * | 1982-08-23 | 1985-08-20 | Queen's University At Kingston | Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins |
| EP0233715B1 (de) * | 1986-01-31 | 1994-05-25 | BEECHAM GROUP plc | Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen |
-
1988
- 1988-10-24 US US07/261,437 patent/US5082772A/en not_active Expired - Fee Related
-
1989
- 1989-10-19 DE DE68925338T patent/DE68925338T2/de not_active Expired - Fee Related
- 1989-10-19 ES ES89310744T patent/ES2082787T3/es not_active Expired - Lifetime
- 1989-10-19 EP EP89310744A patent/EP0366354B1/de not_active Expired - Lifetime
- 1989-10-20 DK DK521489A patent/DK521489A/da not_active Application Discontinuation
- 1989-10-22 IL IL9207989A patent/IL92079A/en not_active IP Right Cessation
- 1989-10-23 JP JP1275750A patent/JPH02242675A/ja active Pending
-
1996
- 1996-01-04 GR GR950403475T patent/GR3018596T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5082772A (en) | 1992-01-21 |
| DE68925338D1 (de) | 1996-02-15 |
| GR3018596T3 (en) | 1996-04-30 |
| JPH02242675A (ja) | 1990-09-27 |
| DE68925338T2 (de) | 1996-06-05 |
| DK521489A (da) | 1990-04-25 |
| EP0366354A3 (de) | 1991-03-20 |
| DK521489D0 (da) | 1989-10-20 |
| ES2082787T3 (es) | 1996-04-01 |
| EP0366354A2 (de) | 1990-05-02 |
| EP0366354B1 (de) | 1996-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |