JPS5539735A - Preparation of deacetyl cephalosporin c - Google Patents

Preparation of deacetyl cephalosporin c

Info

Publication number
JPS5539735A
JPS5539735A JP11204478A JP11204478A JPS5539735A JP S5539735 A JPS5539735 A JP S5539735A JP 11204478 A JP11204478 A JP 11204478A JP 11204478 A JP11204478 A JP 11204478A JP S5539735 A JPS5539735 A JP S5539735A
Authority
JP
Japan
Prior art keywords
streptomyces
cephalosporin
preparation
culture
contact
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11204478A
Other languages
Japanese (ja)
Other versions
JPS6247519B2 (en
Inventor
Yukio Fujisawa
Masaru Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP11204478A priority Critical patent/JPS5539735A/en
Publication of JPS5539735A publication Critical patent/JPS5539735A/en
Publication of JPS6247519B2 publication Critical patent/JPS6247519B2/ja
Granted legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To obtain the title antibiotic useful as an intermediate for the synthesis of cephalosporin in a very high yield, by bringing cephalosporin C into contact with a culture or a substance treated with Streptomyces viridochromogenes, etc.
CONSTITUTION: Cephalosporin C (C) is brought into contact with a culture of or a substance treated with Streptomyces viridochromogenes, Streptomyces olivaceus, Streptomyces griseolus or Streptomyces fradiae to eliminate the acetyl group at the side chain in the 3-position of C with the esterase-like activity. Thus, deacetylcephalosporin C of the formula can be obtained.
COPYRIGHT: (C)1980,JPO&Japio
JP11204478A 1978-09-11 1978-09-11 Preparation of deacetyl cephalosporin c Granted JPS5539735A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11204478A JPS5539735A (en) 1978-09-11 1978-09-11 Preparation of deacetyl cephalosporin c

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11204478A JPS5539735A (en) 1978-09-11 1978-09-11 Preparation of deacetyl cephalosporin c

Publications (2)

Publication Number Publication Date
JPS5539735A true JPS5539735A (en) 1980-03-19
JPS6247519B2 JPS6247519B2 (en) 1987-10-08

Family

ID=14576605

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11204478A Granted JPS5539735A (en) 1978-09-11 1978-09-11 Preparation of deacetyl cephalosporin c

Country Status (1)

Country Link
JP (1) JPS5539735A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082772A (en) * 1988-10-24 1992-01-21 Eli Lilly And Company Process for preparing deacetylcephalosporin c

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111793075A (en) * 2020-07-10 2020-10-20 伊犁川宁生物技术有限公司 Preparation method of high-purity 3-deacetylcephalosporin C sodium salt

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082772A (en) * 1988-10-24 1992-01-21 Eli Lilly And Company Process for preparing deacetylcephalosporin c

Also Published As

Publication number Publication date
JPS6247519B2 (en) 1987-10-08

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