IL92010A - Pyrrolidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
Pyrrolidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL92010A IL92010A IL92010A IL9201089A IL92010A IL 92010 A IL92010 A IL 92010A IL 92010 A IL92010 A IL 92010A IL 9201089 A IL9201089 A IL 9201089A IL 92010 A IL92010 A IL 92010A
- Authority
- IL
- Israel
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- alkyl
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888825454A GB8825454D0 (en) | 1988-10-31 | 1988-10-31 | Pyrrolidine derivatives |
| GB898908387A GB8908387D0 (en) | 1989-04-13 | 1989-04-13 | Pyrrolidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL92010A0 IL92010A0 (en) | 1990-07-12 |
| IL92010A true IL92010A (en) | 1993-06-10 |
Family
ID=26294569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL92010A IL92010A (en) | 1988-10-31 | 1989-10-16 | Pyrrolidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5130323A (hu) |
| EP (1) | EP0367130B1 (hu) |
| JP (1) | JPH0720928B2 (hu) |
| KR (1) | KR900006282A (hu) |
| CN (1) | CN1024791C (hu) |
| AT (1) | ATE143658T1 (hu) |
| AU (1) | AU628406B2 (hu) |
| CA (1) | CA2001750C (hu) |
| DE (1) | DE68927286T2 (hu) |
| DK (1) | DK540589A (hu) |
| ES (1) | ES2092470T3 (hu) |
| FI (1) | FI89594C (hu) |
| GR (1) | GR3021529T3 (hu) |
| HU (2) | HU204033B (hu) |
| IL (1) | IL92010A (hu) |
| NO (1) | NO174886C (hu) |
| PT (1) | PT92147B (hu) |
| RU (1) | RU1819261C (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL86173A (en) * | 1987-05-01 | 1992-02-16 | Fujisawa Pharmaceutical Co | Pyrrolidine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5264453A (en) * | 1988-10-31 | 1993-11-23 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolidine derivatives |
| FR2685325B1 (fr) * | 1991-12-20 | 1994-02-04 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2687146B1 (fr) * | 1992-02-12 | 1994-04-01 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| RU94046180A (ru) * | 1992-07-02 | 1996-10-27 | Фудзисава Фармасьютикал Ко. | Способ получения производного пирролидина и его соли, исходный продукт и способ его получения |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3433801A (en) * | 1966-03-22 | 1969-03-18 | Robins Co Inc A H | 1-aryl-3-(n-lower alkyl amino) pyrrolidines |
| US3509171A (en) * | 1967-09-14 | 1970-04-28 | Robins Co Inc A H | 3-amino-1-carbamyl and thiocarbamyl pyrrolidines |
| US4210660A (en) * | 1978-12-20 | 1980-07-01 | Yamanouchi Pharmaceutical Co., Ltd. | Benzamide derivatives |
| US4785119A (en) * | 1985-10-11 | 1988-11-15 | Tokyo Kasei Kogyo Co., Ltd. | 3-aminopyrrolidine compound and process for preparation thereof |
| GB2205255B (en) * | 1987-04-29 | 1991-07-24 | Pilot Ink Co Ltd | Color changing toy |
| IL86173A (en) * | 1987-05-01 | 1992-02-16 | Fujisawa Pharmaceutical Co | Pyrrolidine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
-
1989
- 1989-10-13 US US07/421,399 patent/US5130323A/en not_active Expired - Lifetime
- 1989-10-16 IL IL92010A patent/IL92010A/xx not_active IP Right Cessation
- 1989-10-26 AU AU43753/89A patent/AU628406B2/en not_active Ceased
- 1989-10-27 DE DE68927286T patent/DE68927286T2/de not_active Expired - Fee Related
- 1989-10-27 EP EP89119959A patent/EP0367130B1/en not_active Expired - Lifetime
- 1989-10-27 AT AT89119959T patent/ATE143658T1/de not_active IP Right Cessation
- 1989-10-27 ES ES89119959T patent/ES2092470T3/es not_active Expired - Lifetime
- 1989-10-30 CA CA002001750A patent/CA2001750C/en not_active Expired - Fee Related
- 1989-10-30 CN CN89108348A patent/CN1024791C/zh not_active Expired - Fee Related
- 1989-10-30 FI FI895139A patent/FI89594C/fi not_active IP Right Cessation
- 1989-10-30 DK DK540589A patent/DK540589A/da not_active Application Discontinuation
- 1989-10-30 KR KR1019890015618A patent/KR900006282A/ko not_active Application Discontinuation
- 1989-10-30 PT PT92147A patent/PT92147B/pt not_active IP Right Cessation
- 1989-10-30 NO NO894325A patent/NO174886C/no unknown
- 1989-10-30 RU SU894742358A patent/RU1819261C/ru active
- 1989-10-30 HU HU895612A patent/HU204033B/hu not_active IP Right Cessation
- 1989-10-31 JP JP1285798A patent/JPH0720928B2/ja not_active Expired - Lifetime
-
1995
- 1995-06-22 HU HU95P/P00373P patent/HU211499A9/hu unknown
-
1996
- 1996-10-31 GR GR960402892T patent/GR3021529T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5130323A (en) | 1992-07-14 |
| FI895139A0 (fi) | 1989-10-30 |
| JPH02152960A (ja) | 1990-06-12 |
| CA2001750C (en) | 1998-09-15 |
| CN1024791C (zh) | 1994-06-01 |
| FI89594B (fi) | 1993-07-15 |
| PT92147B (pt) | 1995-06-30 |
| DK540589D0 (da) | 1989-10-30 |
| FI89594C (fi) | 1993-10-25 |
| NO894325L (no) | 1990-05-02 |
| CA2001750A1 (en) | 1990-04-30 |
| ES2092470T3 (es) | 1996-12-01 |
| DE68927286T2 (de) | 1997-03-06 |
| NO174886C (no) | 1994-07-27 |
| NO174886B (no) | 1994-04-18 |
| HU895612D0 (en) | 1990-01-28 |
| DE68927286D1 (de) | 1996-11-07 |
| ATE143658T1 (de) | 1996-10-15 |
| EP0367130B1 (en) | 1996-10-02 |
| HUT52044A (en) | 1990-06-28 |
| IL92010A0 (en) | 1990-07-12 |
| AU4375389A (en) | 1990-05-03 |
| RU1819261C (ru) | 1993-05-30 |
| PT92147A (pt) | 1990-05-31 |
| GR3021529T3 (en) | 1997-01-31 |
| CN1042355A (zh) | 1990-05-23 |
| HU211499A9 (en) | 1995-11-28 |
| KR900006282A (ko) | 1990-05-07 |
| DK540589A (da) | 1990-05-01 |
| EP0367130A2 (en) | 1990-05-09 |
| AU628406B2 (en) | 1992-09-17 |
| EP0367130A3 (en) | 1991-03-13 |
| HU204033B (en) | 1991-11-28 |
| JPH0720928B2 (ja) | 1995-03-08 |
| NO894325D0 (no) | 1989-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void | ||
| HC | Change of name of proprietor(s) | ||
| ERR | Corrigendum |
Free format text: CORRECT DATE OF APPLICATION: 20090630 |
|
| HK | Corrigendum |
Free format text: CORRECT COUNTRY IN PRIORITY NUMBER CN |
|
| ERR | Corrigendum |
Free format text: CORRECT NAME APPLICANT ASPEN GLOBAL INCORPORATED |
|
| ERR | Corrigendum |
Free format text: ADD DIVISION 113140 |