IL91615A0 - Derivatives of human/bovine basic fibroblast growth factor - Google Patents

Derivatives of human/bovine basic fibroblast growth factor

Info

Publication number
IL91615A0
IL91615A0 IL91615A IL9161589A IL91615A0 IL 91615 A0 IL91615 A0 IL 91615A0 IL 91615 A IL91615 A IL 91615A IL 9161589 A IL9161589 A IL 9161589A IL 91615 A0 IL91615 A0 IL 91615A0
Authority
IL
Israel
Prior art keywords
derivatives
human
bfgf
growth factor
fibroblast growth
Prior art date
Application number
IL91615A
Other languages
English (en)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL91615A0 publication Critical patent/IL91615A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL91615A 1988-09-16 1989-09-12 Derivatives of human/bovine basic fibroblast growth factor IL91615A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888821795A GB8821795D0 (en) 1988-09-16 1988-09-16 New derivatives of human/bovine basic fibroplast growth factor

Publications (1)

Publication Number Publication Date
IL91615A0 true IL91615A0 (en) 1990-04-29

Family

ID=10643728

Family Applications (1)

Application Number Title Priority Date Filing Date
IL91615A IL91615A0 (en) 1988-09-16 1989-09-12 Derivatives of human/bovine basic fibroblast growth factor

Country Status (21)

Country Link
EP (2) EP0363675B1 (fr)
JP (1) JP2888575B2 (fr)
KR (1) KR900702027A (fr)
CN (1) CN1041181A (fr)
AT (1) ATE98693T1 (fr)
AU (1) AU620925B2 (fr)
CA (1) CA1340834C (fr)
DE (1) DE68911461T2 (fr)
DK (1) DK120290A (fr)
ES (1) ES2061855T3 (fr)
FI (1) FI902391A0 (fr)
GB (1) GB8821795D0 (fr)
HU (1) HUT53937A (fr)
IL (1) IL91615A0 (fr)
MY (1) MY104910A (fr)
NO (1) NO902176L (fr)
NZ (1) NZ230621A (fr)
PT (1) PT91719B (fr)
WO (1) WO1990002800A1 (fr)
YU (1) YU179489A (fr)
ZA (1) ZA897020B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143829A (en) * 1990-03-29 1992-09-01 California Biotechnology Inc. High level expression of basic fibroblast growth factor having a homogeneous n-terminus
US5478804A (en) * 1990-09-19 1995-12-26 The Salk Institute For Biological Studies Treatment of tumorigenic pathophysiological conditions with FGF-cytoxic conjugates
US6833354B1 (en) 1990-12-19 2004-12-21 Kaken Pharmaceutical Co., Ltd. Agent for the treatment of bone diseases
JP3135138B2 (ja) * 1990-12-19 2001-02-13 科研製薬株式会社 骨疾患治療剤
DE69205466T2 (de) * 1991-03-21 1996-05-30 Procter & Gamble Mittel zur Kontrolle von Hautfalten, die die Arg-Ser-Arg-Lys-Sequenzen enthalten.
JP3303211B2 (ja) * 1991-04-26 2002-07-15 武田薬品工業株式会社 ｂＦＧＦムテインおよびその製造法
TW275068B (fr) * 1993-09-24 1996-05-01 American Cyanamid Co
AUPO247496A0 (en) 1996-09-23 1996-10-17 Resmed Limited Assisted ventilation to match patient respiratory need
US6214795B1 (en) * 1996-11-12 2001-04-10 Praecis Pharmaceuticals, Inc. Peptide compounds useful for modulating FGF receptor activity
US6274712B1 (en) 1997-12-23 2001-08-14 3-Dimensional Pharmaceuticals, Inc. Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
FR2780416B1 (fr) * 1998-06-10 2002-12-20 Rhone Poulenc Nutrition Animal Procede industriel de production de proteines heterologues chez e. coli et souches utiles pour le procede
EP1207900A2 (fr) * 1999-08-13 2002-05-29 Chiron Corporation Dose d'un facteur angiogenique et procede d'administration correspondant destines a ameliorer le debit sanguin du myocarde
DE69933057T2 (de) * 1999-12-22 2007-03-15 Ortho-Mcneil Pharmaceutical, Inc. Analoge des humanen basischen fibroblasten-wachstumsfactors
CA2430112C (fr) 2000-11-27 2010-07-27 Dnavec Research Inc. Vecteur de paramyxovirus encodant le gene de l'angiogenese et son utilisation
WO2013090919A1 (fr) * 2011-12-16 2013-06-20 Wisconsin Alumni Research Foundation Fgf-2 ayant une stabilité accrue
CN106957359B (zh) * 2016-08-31 2020-04-24 黄志锋 Fgf1突变体及其医药应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81839A0 (en) * 1986-03-14 1987-10-20 Takeda Chemical Industries Ltd Polypeptide,dna and its use
AU1185488A (en) * 1987-01-16 1988-08-10 Amgen, Inc. Production of fibroblast growth factor
JP2526965B2 (ja) * 1987-02-24 1996-08-21 武田薬品工業株式会社 ムテイン，ｄｎａおよびその用途
JP2879148B2 (ja) * 1987-07-07 1999-04-05 サイオス インコーポレイテッド 組換え繊維芽細胞成長因子
EP0326907A1 (fr) * 1988-01-26 1989-08-09 Takeda Chemical Industries, Ltd. Polypeptide, DNA et leur utilisation

Also Published As

Publication number Publication date
DE68911461D1 (de) 1994-01-27
WO1990002800A1 (fr) 1990-03-22
EP0363675A1 (fr) 1990-04-18
NZ230621A (en) 1992-06-25
EP0396664A1 (fr) 1990-11-14
ZA897020B (en) 1990-08-29
ATE98693T1 (de) 1994-01-15
NO902176L (no) 1990-07-13
DK120290A (da) 1990-07-16
MY104910A (en) 1994-06-30
HU895573D0 (en) 1990-11-28
YU179489A (en) 1991-10-31
FI902391A0 (fi) 1990-05-14
CA1340834C (fr) 1999-11-30
AU4317189A (en) 1990-04-02
DE68911461T2 (de) 1994-05-19
GB8821795D0 (en) 1988-10-19
PT91719B (pt) 1995-05-31
AU620925B2 (en) 1992-02-27
EP0363675B1 (fr) 1993-12-15
PT91719A (pt) 1990-03-30
DK120290D0 (da) 1990-05-15
JPH03501855A (ja) 1991-04-25
JP2888575B2 (ja) 1999-05-10
KR900702027A (ko) 1990-12-05
ES2061855T3 (es) 1994-12-16
NO902176D0 (no) 1990-05-15
HUT53937A (en) 1990-12-28
CN1041181A (zh) 1990-04-11

Similar Documents

Publication Publication Date Title
IL91615A0 (en) Derivatives of human/bovine basic fibroblast growth factor
PL322945A1 (en) Novel protein and method of obtaining same
GR3020517T3 (en) Human erythropoietin muteins, their production and their use
EP0458959A4 (en) Novel platelet-derived growth factor b chain analogs and method for homogeneous production thereof
SG49097A1 (en) Nucleotide sequences coding for a protein with urease activity
EP0237966A3 (fr) Facteur humain basique de croissance de fibroblaste
GB8727045D0 (en) Immunoglobulin e competitor
IL92669A (en) TGF beta 1/beta 2: a chimeric transforming growth factor-beta
DK38889D0 (da) Onkogen-indkodet polypeptid med vaekstfaktoraktivitet
EP0276778A3 (fr) Expression à haut niveau de IL-1bêta soluble et mature dans E. coli et dérivés ayant une activité biologique modifiée
EP0315118A3 (fr) ADN codant pour endothéline et son utilisant
HUT62327A (en) Process for producing somatotropins modified in their alfa-helix 1 region and their combination with other mutants
HUT44609A (en) Process for preparing new polypeptides
ATE131175T1 (de) Protein mit fibroblasten-wachstumsfaktor- rezeptoraktivität.
IL85759A0 (en) The cloning of malaria-specific dna sequences,isolation of the gene for the 140 kd protein
DE68927009D1 (de) EXPRESSION UND PROZESSIERUNG VON ACETYLIERTEN FGFs IN HEFEN
AU637589B2 (en) Ancrod proteins, their production and use
IL78278A0 (en) Process for the production of polypeptides,dna sequence encoding desired polypeptide human somatomedin c polypeptide and recombinant dna molecules
ATE130872T1 (de) Ancrod ähnliche proteine, ihre herstellung und verwendung.
Bergonzoni et al. Deletion mutant of basic fibroblast growth factor and production thereof