IL91602A0 - Nitrate esters and pharmaceutical compositions containing them - Google Patents
Nitrate esters and pharmaceutical compositions containing themInfo
- Publication number
- IL91602A0 IL91602A0 IL91602A IL9160289A IL91602A0 IL 91602 A0 IL91602 A0 IL 91602A0 IL 91602 A IL91602 A IL 91602A IL 9160289 A IL9160289 A IL 9160289A IL 91602 A0 IL91602 A0 IL 91602A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- nitrate esters
- nitrate
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C203/00—Esters of nitric or nitrous acid
- C07C203/02—Esters of nitric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C203/00—Esters of nitric or nitrous acid
- C07C203/02—Esters of nitric acid
- C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C203/00—Esters of nitric or nitrous acid
- C07C203/02—Esters of nitric acid
- C07C203/08—Esters of nitric acid having nitrate groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
- C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/28—Hydrogenated naphthalenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8802276A NL8802276A (nl) | 1988-09-15 | 1988-09-15 | Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL91602A0 true IL91602A0 (en) | 1990-04-29 |
Family
ID=19852906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL91602A IL91602A0 (en) | 1988-09-15 | 1989-09-11 | Nitrate esters and pharmaceutical compositions containing them |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5049694A (da) |
| EP (1) | EP0359335A3 (da) |
| JP (1) | JPH02134316A (da) |
| KR (1) | KR900004331A (da) |
| AU (1) | AU638413B2 (da) |
| DK (1) | DK453089A (da) |
| FI (1) | FI894349A7 (da) |
| IL (1) | IL91602A0 (da) |
| NL (1) | NL8802276A (da) |
| NO (1) | NO171904C (da) |
| NZ (1) | NZ230631A (da) |
| PT (1) | PT91701B (da) |
| ZA (1) | ZA896982B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1243367B (it) * | 1990-07-26 | 1994-06-10 | Italfarmaco Spa | Derivati acidi benzoici sostituiti ad attivita' cardiovascolare |
| NL9001955A (nl) * | 1990-09-05 | 1992-04-01 | Cedona Pharm Bv | Nieuwe thiazolidinederivaten. |
| JP3454531B2 (ja) * | 1991-11-07 | 2003-10-06 | 三共株式会社 | ニトロキシアルキルアミド誘導体 |
| US5646181A (en) * | 1992-07-02 | 1997-07-08 | Research Foundation Of State University Of New York | Method and compositions for treating impotence |
| IT1256450B (it) * | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
| CA2158368A1 (en) * | 1993-03-15 | 1994-09-29 | Jan Bron | Use of substituted alkyl nitrates for the treatment of pathologically raised intraocular pressure |
| ES2065291B1 (es) * | 1993-07-30 | 1995-10-01 | Prodesfarma Sa | "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente" |
| DK0722434T3 (da) * | 1993-10-06 | 1998-11-16 | Nicox Sa | Salpetersyreestere, der har anti-inflammatorisk og/eller analgetisk aktivitet og fremgangsmåder til deres fremstilling |
| JPH09507672A (ja) * | 1994-01-19 | 1997-08-05 | ビイク ネダーラント ベスローテン フェンノートシャップ | ニトロキシ基含有ベンジルアミン誘導体及び循環器疾患並びに眼内圧増加の治療のためのその使用 |
| US5925658A (en) * | 1995-03-02 | 1999-07-20 | Sankyo Company, Limited | Optically active thiazolidinone derivative |
| US5807847A (en) * | 1996-06-04 | 1998-09-15 | Queen's University At Kingston | Nitrate esters |
| US20050137191A1 (en) * | 1996-06-04 | 2005-06-23 | Thatcher Gregory R. | Nitrate esters and their use for mitigating cellular damage |
| US6310052B1 (en) | 1996-06-04 | 2001-10-30 | Queen's University At Kingston | Nitrate esters and their use for neurological conditions |
| US7115661B1 (en) | 1999-12-29 | 2006-10-03 | Queen's University At Kingston | Methods and compositions for mitigating pain |
| IL120531A (en) * | 1997-03-26 | 2006-12-31 | Yissum Res Dev Co | Nitric oxide donors and pharmaceutical compositions containing them |
| RU2125040C1 (ru) * | 1997-04-23 | 1999-01-20 | Институт химической физики в Черноголовке РАН | Производные янтарной кислоты, способ их получения, промежуточные соединения для их синтеза и способ получения промежуточных соединений |
| RU2146243C1 (ru) * | 1998-04-22 | 2000-03-10 | Институт химической физики в Черноголовке РАН | Нитраты спиртов, содержащие амидную, динитрометиленовую и нитроаминную группы, способ их получения, 3-(ациламинодинитроалкил)-тетрагидро-1,3-оксазолы и - оксазины, способ их получения |
| US6056966A (en) * | 1998-05-18 | 2000-05-02 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for treating impotence |
| AU2003265769A1 (en) * | 2002-05-02 | 2003-11-17 | Ciphergen Biosystems, Inc. | Biochips with surfaces coated with polysaccharide based hydrogels |
| JP4891982B2 (ja) * | 2008-12-15 | 2012-03-07 | スガツネ工業株式会社 | ２軸ヒンジ装置及び携帯機器 |
| WO2013060673A1 (en) * | 2011-10-24 | 2013-05-02 | Nicox S.A. | Quinone based nitric oxide donating compounds |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2139364A (en) * | 1937-03-22 | 1938-12-06 | Shell Dev | Alpha-substituted glycerol nitrates |
| NL49919C (da) * | 1938-02-10 | |||
| US2294849A (en) * | 1938-08-20 | 1942-09-01 | Sharples Chemicals Inc | Manufacture of nitric acid esters |
| US2549687A (en) * | 1947-11-21 | 1951-04-17 | Duriron Co | Heat exchanger |
| GB713329A (en) * | 1951-01-08 | 1954-08-11 | Nat Res Dev | Improvements in or relating to production of nitric acid esters of higher alcohols and glycols |
| US2683164A (en) * | 1951-12-21 | 1954-07-06 | Trojan Powder Co | Preparation of 1, 2, 6-hexanetriol trinitrate |
| US2742492A (en) * | 1954-07-29 | 1956-04-17 | Ethyl Corp | Nitrate formulations |
| NL98269C (da) * | 1956-02-24 | |||
| NL110701C (da) * | 1960-03-14 | |||
| US3428667A (en) * | 1962-09-20 | 1969-02-18 | Aerojet General Co | N,n-dinitramines of certain organic compounds and process |
| US3419571A (en) * | 1966-04-06 | 1968-12-31 | Warner Lambert Pharmaceutical | Method for relieving coronary insufficiency |
| US3409620A (en) * | 1967-02-06 | 1968-11-05 | Mario Biazzi Sa Dr Ing | Continuous manufacture in vacuum of nitric esters and/or organic nitro compounds |
| US3470231A (en) * | 1967-05-29 | 1969-09-30 | Us Navy | Method of stabilizing nitric acid esters |
| US3853891A (en) * | 1971-06-16 | 1974-12-10 | Sandoz Ag | N-(n-(cyanoalkyl)-n-nitroso)amino-aminoalcohol |
| US4336408A (en) * | 1977-11-25 | 1982-06-22 | Thiokol Corporation | 2-Hydroxymethyl-1,3-propanediol preparation |
| JPS56113748A (en) * | 1980-02-13 | 1981-09-07 | Kowa Co | Aminoethanol derivative and its preparation |
| US4417903A (en) * | 1982-10-15 | 1983-11-29 | Ethyl Corporation | Diesel fuel composition |
| DE3305690A1 (de) * | 1983-02-18 | 1984-08-30 | Heinrich Mack Nachf., 7918 Illertissen | Glycerinmononitrate zur behandlung der angina pectoris |
| US4479905A (en) * | 1983-09-19 | 1984-10-30 | Ethyl Corporation | Nitration process |
| DE3443998A1 (de) * | 1984-12-01 | 1986-06-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| DE3512627A1 (de) * | 1985-04-06 | 1986-10-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel |
-
1988
- 1988-09-15 NL NL8802276A patent/NL8802276A/nl not_active Application Discontinuation
-
1989
- 1989-09-11 IL IL91602A patent/IL91602A0/xx unknown
- 1989-09-12 EP EP19890202294 patent/EP0359335A3/en not_active Withdrawn
- 1989-09-13 PT PT91701A patent/PT91701B/pt not_active IP Right Cessation
- 1989-09-13 ZA ZA896982A patent/ZA896982B/xx unknown
- 1989-09-13 NZ NZ230631A patent/NZ230631A/xx unknown
- 1989-09-13 AU AU41330/89A patent/AU638413B2/en not_active Ceased
- 1989-09-14 DK DK453089A patent/DK453089A/da not_active Application Discontinuation
- 1989-09-14 FI FI894349A patent/FI894349A7/fi not_active IP Right Cessation
- 1989-09-14 NO NO893686A patent/NO171904C/no unknown
- 1989-09-14 US US07/407,355 patent/US5049694A/en not_active Expired - Fee Related
- 1989-09-16 JP JP1240497A patent/JPH02134316A/ja active Pending
- 1989-09-16 KR KR1019890013351A patent/KR900004331A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| FI894349L (fi) | 1990-03-16 |
| DK453089D0 (da) | 1989-09-14 |
| EP0359335A3 (en) | 1991-03-06 |
| NL8802276A (nl) | 1990-04-02 |
| PT91701B (pt) | 1995-06-30 |
| NZ230631A (en) | 1993-01-27 |
| AU638413B2 (en) | 1993-07-01 |
| DK453089A (da) | 1990-03-16 |
| PT91701A (pt) | 1990-03-30 |
| US5049694A (en) | 1991-09-17 |
| NO893686D0 (no) | 1989-09-14 |
| JPH02134316A (ja) | 1990-05-23 |
| EP0359335A2 (en) | 1990-03-21 |
| KR900004331A (ko) | 1990-04-12 |
| NO893686L (no) | 1990-03-16 |
| FI894349A7 (fi) | 1990-03-16 |
| ZA896982B (en) | 1990-06-27 |
| FI894349A0 (fi) | 1989-09-14 |
| NO171904C (no) | 1993-05-19 |
| NO171904B (no) | 1993-02-08 |
| AU4133089A (en) | 1990-03-22 |
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