IL90733A - Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type - Google Patents
Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this typeInfo
- Publication number
- IL90733A IL90733A IL9073389A IL9073389A IL90733A IL 90733 A IL90733 A IL 90733A IL 9073389 A IL9073389 A IL 9073389A IL 9073389 A IL9073389 A IL 9073389A IL 90733 A IL90733 A IL 90733A
- Authority
- IL
- Israel
- Prior art keywords
- quinoxaline
- mmol
- dihydroxy
- water
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
- C07D517/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK356788A DK160941C (da) | 1988-06-28 | 1988-06-28 | Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar |
Publications (2)
Publication Number | Publication Date |
---|---|
IL90733A0 IL90733A0 (en) | 1990-01-18 |
IL90733A true IL90733A (en) | 1994-02-27 |
Family
ID=8124358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9073389A IL90733A (en) | 1988-06-28 | 1989-06-23 | Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type |
Country Status (18)
Country | Link |
---|---|
US (5) | US4977155A (no) |
EP (1) | EP0348872B1 (no) |
JP (1) | JPH0248578A (no) |
KR (1) | KR910000735A (no) |
AT (1) | ATE95181T1 (no) |
AU (1) | AU619863B2 (no) |
CA (1) | CA1326670C (no) |
DE (1) | DE68909513T2 (no) |
DK (1) | DK160941C (no) |
ES (1) | ES2059636T3 (no) |
FI (1) | FI91259C (no) |
IE (1) | IE64289B1 (no) |
IL (1) | IL90733A (no) |
NO (1) | NO169390C (no) |
NZ (1) | NZ229730A (no) |
PH (1) | PH27565A (no) |
PT (1) | PT91010B (no) |
ZA (1) | ZA894903B (no) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK716188D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
US5153195A (en) * | 1988-12-22 | 1992-10-06 | Novo Nordisk A/S | Quinoxaline compounds and their preparation and use |
PT99864B (pt) | 1990-12-21 | 1999-06-30 | Schering Ag | Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato |
US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
US5153196A (en) * | 1991-06-05 | 1992-10-06 | Eli Lilly And Company | Excitatory amino acid receptor antagonists and methods for the use thereof |
DK162491D0 (da) * | 1991-09-20 | 1991-09-20 | Novo Nordisk As | Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne |
EP0647137B1 (en) * | 1992-06-22 | 2008-08-13 | The Regents Of The University Of California | Glycine receptor antagonists and the use thereof |
AU680632B2 (en) | 1992-10-13 | 1997-08-07 | Neurosearch A/S | Quinoxalinedione derivatives as EAA antagonists |
DE4310523A1 (de) * | 1993-03-31 | 1994-10-06 | Basf Ag | Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen |
US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
US5576323A (en) * | 1993-12-03 | 1996-11-19 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
AU688459B2 (en) * | 1994-04-08 | 1998-03-12 | Shionogi & Co., Ltd. | Oxopyridinylquinoxaline derivative |
US5476851A (en) * | 1994-09-08 | 1995-12-19 | Rhone-Poulenc Rorer Pharmaceuticals, Inc. | Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase |
US5719153A (en) * | 1995-08-15 | 1998-02-17 | American Home Products Corporation | 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones |
US5824662A (en) | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
IL128718A0 (en) | 1996-09-27 | 2000-01-31 | Guildford Pharmaceuticals Inc | Naaldase compositions |
BR9807083A (pt) | 1997-01-23 | 2000-04-18 | Smithkline Beckman Corp | Antagonistas ao receptor de il-8 |
FR2760237B1 (fr) * | 1997-02-28 | 1999-04-16 | Rhone Poulenc Rorer Sa | Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant |
US6288075B1 (en) | 1998-02-26 | 2001-09-11 | Rhone-Poulenc Rorer S.A. | Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same |
FR2766487B1 (fr) * | 1997-07-28 | 1999-08-27 | Rhone Poulenc Rorer Sa | Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant |
US6262044B1 (en) | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
WO1999046267A1 (en) * | 1998-03-12 | 1999-09-16 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
JP2009286778A (ja) * | 2008-04-30 | 2009-12-10 | Sumitomo Chemical Co Ltd | tert−ブチル3−アミノピペリジン−1−カルボキシレートの製造方法およびその中間体 |
EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
CN113549087A (zh) * | 2020-04-26 | 2021-10-26 | 北京鼎材科技有限公司 | 一种化合物及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1246578A (en) * | 1982-03-29 | 1988-12-13 | John H. Musser | 2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents |
DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
-
1988
- 1988-06-28 DK DK356788A patent/DK160941C/da not_active IP Right Cessation
-
1989
- 1989-06-21 IE IE200889A patent/IE64289B1/en not_active IP Right Cessation
- 1989-06-22 US US07/369,762 patent/US4977155A/en not_active Expired - Fee Related
- 1989-06-23 IL IL9073389A patent/IL90733A/en not_active IP Right Cessation
- 1989-06-23 CA CA000603702A patent/CA1326670C/en not_active Expired - Fee Related
- 1989-06-26 ES ES89111622T patent/ES2059636T3/es not_active Expired - Lifetime
- 1989-06-26 EP EP89111622A patent/EP0348872B1/en not_active Expired - Lifetime
- 1989-06-26 AT AT89111622T patent/ATE95181T1/de active
- 1989-06-26 DE DE89111622T patent/DE68909513T2/de not_active Expired - Fee Related
- 1989-06-27 AU AU37077/89A patent/AU619863B2/en not_active Ceased
- 1989-06-27 NZ NZ229730A patent/NZ229730A/en unknown
- 1989-06-27 NO NO892680A patent/NO169390C/no unknown
- 1989-06-28 ZA ZA894903A patent/ZA894903B/xx unknown
- 1989-06-28 PH PH38872A patent/PH27565A/en unknown
- 1989-06-28 JP JP1164091A patent/JPH0248578A/ja active Pending
- 1989-06-28 FI FI893170A patent/FI91259C/fi not_active IP Right Cessation
- 1989-06-28 PT PT91010A patent/PT91010B/pt not_active IP Right Cessation
- 1989-06-28 KR KR1019890008933A patent/KR910000735A/ko not_active Application Discontinuation
-
1990
- 1990-08-20 US US07/570,019 patent/US5075306A/en not_active Expired - Fee Related
- 1990-08-22 US US07/570,819 patent/US5109001A/en not_active Expired - Fee Related
- 1990-08-22 US US07/570,903 patent/US5057516A/en not_active Expired - Fee Related
- 1990-08-23 US US07/572,172 patent/US5079250A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK356788D0 (da) | 1988-06-28 |
NO169390B (no) | 1992-03-09 |
EP0348872B1 (en) | 1993-09-29 |
IL90733A0 (en) | 1990-01-18 |
US4977155A (en) | 1990-12-11 |
FI91259C (fi) | 1994-06-10 |
US5109001A (en) | 1992-04-28 |
DK356788A (da) | 1990-03-21 |
NO169390C (no) | 1992-06-17 |
NZ229730A (en) | 1991-07-26 |
US5075306A (en) | 1991-12-24 |
IE892008L (en) | 1989-12-28 |
JPH0248578A (ja) | 1990-02-19 |
PT91010B (pt) | 1995-01-31 |
KR910000735A (ko) | 1991-01-30 |
DE68909513D1 (de) | 1993-11-04 |
DK160941C (da) | 1991-10-21 |
US5057516A (en) | 1991-10-15 |
DK160941B (da) | 1991-05-06 |
PT91010A (pt) | 1989-12-29 |
CA1326670C (en) | 1994-02-01 |
FI91259B (fi) | 1994-02-28 |
AU3707789A (en) | 1990-01-04 |
US5079250A (en) | 1992-01-07 |
NO892680L (no) | 1989-12-29 |
DE68909513T2 (de) | 1994-01-20 |
EP0348872A1 (en) | 1990-01-03 |
AU619863B2 (en) | 1992-02-06 |
PH27565A (en) | 1993-08-18 |
FI893170A0 (fi) | 1989-06-28 |
IE64289B1 (en) | 1995-07-26 |
ATE95181T1 (de) | 1993-10-15 |
NO892680D0 (no) | 1989-06-27 |
ZA894903B (en) | 1990-03-28 |
FI893170A (fi) | 1989-12-29 |
ES2059636T3 (es) | 1994-11-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4977155A (en) | 1,2,3-triazolo compounds | |
US4948794A (en) | Cycloalkyl or benzyl-6-substituted-quinoxalinediones | |
US4889855A (en) | Heterocyclic compounds and their preparation and use | |
US5081123A (en) | Quinoxaline compound and their preparation and use | |
US5061706A (en) | 2,3-quinoxalinediones for use as neuroleptics | |
CA1298298C (en) | Quinoxaline compounds and their preparation and use | |
US4812458A (en) | 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics | |
US5308845A (en) | Quinoxaline compounds and their preparation and use | |
US5153195A (en) | Quinoxaline compounds and their preparation and use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |