IL90129A0 - Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase - Google Patents

Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase

Info

Publication number
IL90129A0
IL90129A0 IL90129A IL9012989A IL90129A0 IL 90129 A0 IL90129 A0 IL 90129A0 IL 90129 A IL90129 A IL 90129A IL 9012989 A IL9012989 A IL 9012989A IL 90129 A0 IL90129 A0 IL 90129A0
Authority
IL
Israel
Prior art keywords
deacetoxycephalosporin
synthetase
encode
expression vectors
dna
Prior art date
Application number
IL90129A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL90129A0 publication Critical patent/IL90129A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL90129A 1988-05-09 1989-05-01 Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase IL90129A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/192,273 US5070020A (en) 1988-05-09 1988-05-09 Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase

Publications (1)

Publication Number Publication Date
IL90129A0 true IL90129A0 (en) 1989-12-15

Family

ID=22708994

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90129A IL90129A0 (en) 1988-05-09 1989-05-01 Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase

Country Status (7)

Country Link
US (1) US5070020A (hu)
EP (1) EP0341892A1 (hu)
JP (1) JPH0227984A (hu)
AU (1) AU622662B2 (hu)
DK (1) DK217889A (hu)
HU (1) HU209581B (hu)
IL (1) IL90129A0 (hu)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709859B1 (en) * 1986-01-31 2004-03-23 Beecham Group P.L.C. Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.
CA2045951A1 (en) * 1990-07-06 1992-01-07 Steven Kovacevic Recombinant dna expression vectors and dna compounds that encode deacetylcephalosporin c synthase activity
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
RO116648B1 (ro) * 1991-10-15 2001-04-30 Merck & Co Inc Bioprocedeu pentru prepararea acidului 7-amino-3-deacetil-cefalosporanic si a acidului 7-aminocefalosporanic
US5554507A (en) * 1992-07-30 1996-09-10 American Cyanamid Company Bacillus subtilis siderophore genes
PL180565B1 (pl) * 1993-07-30 2001-02-28 Gist Brocades Bv Sposób wytwarzaniai wydzielania kwasu 7-aminodezacetoksycefalosporanowego (7-ADCA) PL PL
EP0763129A1 (en) * 1994-04-22 1997-03-19 Merck & Co. Inc. Dna encoding cephamycin biosynthesis late enzymes
CN101659926A (zh) * 1994-06-30 2010-03-03 诺沃奇梅兹有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
US6020151A (en) * 1995-06-02 2000-02-01 Dsm N.V. Process for the production of 7-ADCA via expandase activity on penicillin G
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
AU1097297A (en) * 1995-11-27 1997-06-19 Gist-Brocades B.V. Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin
AU4114697A (en) * 1996-07-16 1998-02-09 Gist-Brocades B.V. Improved process for the production of adipoyl cephalosporins
US6071724A (en) * 1996-12-13 2000-06-06 Eli Lilly And Company Streptococcus pneumoniaegene sequence era
EP1078069B1 (en) 1998-05-19 2008-02-13 DSM IP Assets B.V. Improved in vivo production of cephalosporins
US6720479B1 (en) * 1998-05-29 2004-04-13 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US7094953B2 (en) 1998-05-29 2006-08-22 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US6284483B1 (en) * 1999-10-06 2001-09-04 Board Of Trustees Operating Michigan State University Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate
EP1409514A4 (en) * 2001-06-22 2005-02-02 Ceres Inc CHIMERIC HISTON ACETYL TRANSFERASE POLYPEPTIDES
EP1900815B1 (en) 2001-07-12 2016-09-07 University of Massachusetts In vivo production of small interfering RNAs that mediate gene silencing
KR101021695B1 (ko) 2001-07-12 2011-03-15 유니버시티 오브 매사추세츠 유전자 불활성화를 매개하는 소형 간섭 ｒｎａ의 생체내 제조
US6699699B2 (en) 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
WO2004106347A1 (en) 2003-05-28 2004-12-09 Dsm Ip Assets B.V. Cephem compound
PT1633767T (pt) 2003-06-02 2019-02-27 Univ Massachusetts Métodos e composições para controlar a eficácia do silenciamento de arn
ES2864206T3 (es) 2003-06-02 2021-10-13 Univ Massachusetts Métodos y composiciones para mejorar la eficacia y la especificidad del ARNi
WO2007107810A1 (en) * 2006-03-20 2007-09-27 Council Of Scientific And Industrial Research A method for detecting the presence of water born pathogens and indicator microorganism
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
WO2010074760A1 (en) * 2008-12-22 2010-07-01 Greenlight Biosciences Compositions and methods for the production of a compound
KR20130071433A (ko) 2010-05-07 2013-06-28 그린라이트 바이오사이언시스, 아이엔씨. 효소의 재배치를 통한 대사 경로에서의 흐름의 제어 방법
EP2611922A1 (en) 2010-08-31 2013-07-10 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
EP2753702B1 (en) 2011-09-09 2021-12-15 GreenLight Biosciences, Inc. Cell-free preparation of carbapenems
AU2014306074B2 (en) 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
BR112017020690A2 (pt) 2015-03-30 2018-06-26 Greenlight Biosciences Inc produção livre de células de ácido ribonucleico
SG11201808721YA (en) 2016-04-06 2018-11-29 Greenlight Biosciences Inc Cell-free production of ribonucleic acid
AR113764A1 (es) 2017-10-11 2020-06-10 Greenlight Biosciences Inc Métodos y composiciones para la producción de nucleósido trifosfato y ácido ribonucleico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
US4510246A (en) * 1982-08-23 1985-04-09 Queen's University At Kingston Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.

Also Published As

Publication number Publication date
DK217889D0 (da) 1989-05-03
EP0341892A1 (en) 1989-11-15
AU3408289A (en) 1989-11-09
HUT51672A (en) 1990-05-28
AU622662B2 (en) 1992-04-16
US5070020A (en) 1991-12-03
JPH0227984A (ja) 1990-01-30
HU209581B (en) 1994-08-29
DK217889A (da) 1989-11-13

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