IL89588A0 - 5-substituted imidazo(4,5-c)pyridines and pharmaceutical compositions containing them - Google Patents

5-substituted imidazo(4,5-c)pyridines and pharmaceutical compositions containing them

Info

Publication number
IL89588A0
IL89588A0 IL89588A IL8958889A IL89588A0 IL 89588 A0 IL89588 A0 IL 89588A0 IL 89588 A IL89588 A IL 89588A IL 8958889 A IL8958889 A IL 8958889A IL 89588 A0 IL89588 A0 IL 89588A0
Authority
IL
Israel
Prior art keywords
carbon atoms
alkyl
substituted
group
halogen
Prior art date
Application number
IL89588A
Other languages
English (en)
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/167,671 external-priority patent/US4914108A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL89588A0 publication Critical patent/IL89588A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL89588A 1988-03-14 1989-03-13 5-substituted imidazo(4,5-c)pyridines and pharmaceutical compositions containing them IL89588A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/167,671 US4914108A (en) 1988-03-14 1988-03-14 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US07/317,871 US5019581A (en) 1988-03-14 1989-03-06 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity

Publications (1)

Publication Number Publication Date
IL89588A0 true IL89588A0 (en) 1989-09-10

Family

ID=26863369

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89588A IL89588A0 (en) 1988-03-14 1989-03-13 5-substituted imidazo(4,5-c)pyridines and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US5019581A (sv)
EP (1) EP0344414B1 (sv)
JP (1) JP2714426B2 (sv)
KR (1) KR890014537A (sv)
AT (1) ATE112774T1 (sv)
AU (1) AU625058B2 (sv)
CA (1) CA1337072C (sv)
DE (1) DE68918755T2 (sv)
DK (1) DK169872B1 (sv)
ES (1) ES2061753T3 (sv)
FI (1) FI91407C (sv)
IL (1) IL89588A0 (sv)
NO (1) NO169965C (sv)
NZ (1) NZ228336A (sv)
PH (1) PH26967A (sv)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7648998B2 (en) 2003-12-22 2010-01-19 K.U. Leuven Research & Development Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
US7737162B2 (en) 2002-07-03 2010-06-15 Gilead Sciences, Inc. Viral inhibitors
US7754720B2 (en) 2006-07-07 2010-07-13 Gilead Sciences, Inc. Pyridazine compound and use thereof
US7795276B2 (en) 2004-12-21 2010-09-14 Gilead Sciences, Inc. Imiadazo[4,5-c] pyridine compound and method of antiviral treatment

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227384A (en) * 1988-03-14 1993-07-13 G. D. Searle & Co. 5-substituted [4,5-c] imidazopyridines and pharmaceutical use thereof
US5302601A (en) * 1988-03-14 1994-04-12 G. D. Searle & Co. 5-substituted imidazo[4,5-c]pyridines
US4990518A (en) * 1989-09-13 1991-02-05 G. D. Searle & Co. Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines
GB9116056D0 (en) * 1991-07-24 1991-09-11 British Bio Technology Compounds
US5223539A (en) * 1991-11-22 1993-06-29 G. D. Searle & Co. N,n-di-alkyl(phenoxy)benzamide derivatives
US5208242A (en) * 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5262426A (en) * 1993-01-22 1993-11-16 G. D. Searle & Co. N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists
US5360907A (en) * 1993-06-14 1994-11-01 G.D. Searle & Co. Pyrrolo[3,2-B]pyridinylalkyl benzamide derivatives
US5496855A (en) * 1995-01-27 1996-03-05 Smithkline Beecham Corp. Anti-inflammatory compounds
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
ZA832938B (en) * 1982-05-03 1984-12-24 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7737162B2 (en) 2002-07-03 2010-06-15 Gilead Sciences, Inc. Viral inhibitors
US8779141B2 (en) 2002-07-03 2014-07-15 Gilead Sciences, Inc. Viral inhibitors
US7648998B2 (en) 2003-12-22 2010-01-19 K.U. Leuven Research & Development Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
US8329727B2 (en) 2003-12-22 2012-12-11 Gilead Sciences, Inc. Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
US7795276B2 (en) 2004-12-21 2010-09-14 Gilead Sciences, Inc. Imiadazo[4,5-c] pyridine compound and method of antiviral treatment
US7754720B2 (en) 2006-07-07 2010-07-13 Gilead Sciences, Inc. Pyridazine compound and use thereof
US7956184B2 (en) 2006-07-07 2011-06-07 Gilead Sciences, Inc. Pyridazine compound and use thereof
US8569487B2 (en) 2006-07-07 2013-10-29 Gilead Sciences, Inc. Pyridazine compound and use thereof

Also Published As

Publication number Publication date
DE68918755T2 (de) 1995-03-09
AU625058B2 (en) 1992-07-02
NO891058D0 (no) 1989-03-13
AU3127089A (en) 1989-09-14
EP0344414A1 (en) 1989-12-06
FI891200A0 (sv) 1989-03-14
DK121189A (da) 1989-09-15
NO891058L (no) 1989-09-15
US5019581A (en) 1991-05-28
KR890014537A (ko) 1989-10-24
NO169965C (no) 1992-08-26
ES2061753T3 (es) 1994-12-16
NO169965B (no) 1992-05-18
JP2714426B2 (ja) 1998-02-16
JPH01316378A (ja) 1989-12-21
ATE112774T1 (de) 1994-10-15
FI91407B (sv) 1994-03-15
FI891200A (sv) 1989-09-15
NZ228336A (en) 1992-01-29
FI91407C (sv) 1994-06-27
DE68918755D1 (de) 1994-11-17
DK121189D0 (da) 1989-03-13
EP0344414B1 (en) 1994-10-12
CA1337072C (en) 1995-09-19
PH26967A (en) 1992-12-28
DK169872B1 (da) 1995-03-20

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Legal Events

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