FI891200A0 - Förfarande för framställning av terapeutiskt användbara 5-substituerade /4,5-c/imidazopyridinderivat - Google Patents

Förfarande för framställning av terapeutiskt användbara 5-substituerade /4,5-c/imidazopyridinderivat

Info

Publication number
FI891200A0
FI891200A0 FI891200A FI891200A FI891200A0 FI 891200 A0 FI891200 A0 FI 891200A0 FI 891200 A FI891200 A FI 891200A FI 891200 A FI891200 A FI 891200A FI 891200 A0 FI891200 A0 FI 891200A0
Authority
FI
Finland
Prior art keywords
carbon atoms
alkyl
substituted
group
halogen
Prior art date
Application number
FI891200A
Other languages
English (en)
Finnish (fi)
Other versions
FI91407B (sv
FI91407C (sv
FI891200A (sv
Inventor
Ish K Khanna
Roger Nosal
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/167,671 external-priority patent/US4914108A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of FI891200A0 publication Critical patent/FI891200A0/sv
Publication of FI891200A publication Critical patent/FI891200A/sv
Publication of FI91407B publication Critical patent/FI91407B/sv
Application granted granted Critical
Publication of FI91407C publication Critical patent/FI91407C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI891200A 1988-03-14 1989-03-14 Förfarande för framställning av terapeutiskt användbara 5-substituerade /4,5-c/imidazopyridinderivat FI91407C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/167,671 US4914108A (en) 1988-03-14 1988-03-14 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US16767188 1988-03-14
US07/317,871 US5019581A (en) 1988-03-14 1989-03-06 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US31787189 1989-03-06

Publications (4)

Publication Number Publication Date
FI891200A0 true FI891200A0 (sv) 1989-03-14
FI891200A FI891200A (sv) 1989-09-15
FI91407B FI91407B (sv) 1994-03-15
FI91407C FI91407C (sv) 1994-06-27

Family

ID=26863369

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891200A FI91407C (sv) 1988-03-14 1989-03-14 Förfarande för framställning av terapeutiskt användbara 5-substituerade /4,5-c/imidazopyridinderivat

Country Status (15)

Country Link
US (1) US5019581A (sv)
EP (1) EP0344414B1 (sv)
JP (1) JP2714426B2 (sv)
KR (1) KR890014537A (sv)
AT (1) ATE112774T1 (sv)
AU (1) AU625058B2 (sv)
CA (1) CA1337072C (sv)
DE (1) DE68918755T2 (sv)
DK (1) DK169872B1 (sv)
ES (1) ES2061753T3 (sv)
FI (1) FI91407C (sv)
IL (1) IL89588A0 (sv)
NO (1) NO169965C (sv)
NZ (1) NZ228336A (sv)
PH (1) PH26967A (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302601A (en) * 1988-03-14 1994-04-12 G. D. Searle & Co. 5-substituted imidazo[4,5-c]pyridines
US5227384A (en) * 1988-03-14 1993-07-13 G. D. Searle & Co. 5-substituted [4,5-c] imidazopyridines and pharmaceutical use thereof
US4990518A (en) * 1989-09-13 1991-02-05 G. D. Searle & Co. Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines
GB9116056D0 (en) * 1991-07-24 1991-09-11 British Bio Technology Compounds
US5223539A (en) * 1991-11-22 1993-06-29 G. D. Searle & Co. N,n-di-alkyl(phenoxy)benzamide derivatives
US5208242A (en) * 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5262426A (en) * 1993-01-22 1993-11-16 G. D. Searle & Co. N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists
US5360907A (en) * 1993-06-14 1994-11-01 G.D. Searle & Co. Pyrrolo[3,2-B]pyridinylalkyl benzamide derivatives
US5496855A (en) * 1995-01-27 1996-03-05 Smithkline Beecham Corp. Anti-inflammatory compounds
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7648998B2 (en) * 2003-12-22 2010-01-19 K.U. Leuven Research & Development Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
AU2005319167B2 (en) * 2004-12-21 2011-09-29 Gilead Sciences, Inc. Imidazo[4,5-C]pyridine compound and method of antiviral treatment
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
WO2008005519A2 (en) * 2006-07-07 2008-01-10 Gilead Sciences, Inc. Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
ZA832938B (en) * 1982-05-03 1984-12-24 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
CA1337072C (en) 1995-09-19
US5019581A (en) 1991-05-28
EP0344414A1 (en) 1989-12-06
ES2061753T3 (es) 1994-12-16
DK169872B1 (da) 1995-03-20
FI91407B (sv) 1994-03-15
PH26967A (en) 1992-12-28
DK121189A (da) 1989-09-15
NO891058L (no) 1989-09-15
ATE112774T1 (de) 1994-10-15
NZ228336A (en) 1992-01-29
EP0344414B1 (en) 1994-10-12
NO169965C (no) 1992-08-26
KR890014537A (ko) 1989-10-24
FI91407C (sv) 1994-06-27
DE68918755T2 (de) 1995-03-09
JP2714426B2 (ja) 1998-02-16
NO169965B (no) 1992-05-18
AU625058B2 (en) 1992-07-02
JPH01316378A (ja) 1989-12-21
IL89588A0 (en) 1989-09-10
FI891200A (sv) 1989-09-15
DE68918755D1 (de) 1994-11-17
DK121189D0 (da) 1989-03-13
AU3127089A (en) 1989-09-14
NO891058D0 (no) 1989-03-13

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: G D SEARLE & CO.