IL89214A - חומצות 4-פירידיל-1, 3-דיאוקסן- 5-איל אלקנואיות, תהליך להכנתן ותכשירים תרופתיים המכילים אותן - Google Patents

חומצות 4-פירידיל-1, 3-דיאוקסן- 5-איל אלקנואיות, תהליך להכנתן ותכשירים תרופתיים המכילים אותן

Info

Publication number
IL89214A
IL89214A IL8921489A IL8921489A IL89214A IL 89214 A IL89214 A IL 89214A IL 8921489 A IL8921489 A IL 8921489A IL 8921489 A IL8921489 A IL 8921489A IL 89214 A IL89214 A IL 89214A
Authority
IL
Israel
Prior art keywords
formula
pyridyl
compound
acid
hydroxy
Prior art date
Application number
IL8921489A
Other languages
English (en)
Inventor
Andrew George Brewster
George Robert Brown
Alan Wellington Faull
Reginald Jessup
Michael James Smithers
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888803516A external-priority patent/GB8803516D0/en
Priority claimed from GB888824666A external-priority patent/GB8824666D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL89214A publication Critical patent/IL89214A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
IL8921489A 1988-02-16 1989-02-07 חומצות 4-פירידיל-1, 3-דיאוקסן- 5-איל אלקנואיות, תהליך להכנתן ותכשירים תרופתיים המכילים אותן IL89214A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888803516A GB8803516D0 (en) 1988-02-16 1988-02-16 Heterocyclic compounds
GB888824666A GB8824666D0 (en) 1988-10-21 1988-10-21 Pyridine derivatives

Publications (1)

Publication Number Publication Date
IL89214A true IL89214A (he) 1994-01-25

Family

ID=26293498

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8921489A IL89214A (he) 1988-02-16 1989-02-07 חומצות 4-פירידיל-1, 3-דיאוקסן- 5-איל אלקנואיות, תהליך להכנתן ותכשירים תרופתיים המכילים אותן

Country Status (24)

Country Link
US (1) US5166213A (he)
EP (1) EP0329360B1 (he)
JP (1) JP2812697B2 (he)
KR (1) KR0145725B1 (he)
CN (1) CN1040753C (he)
AR (1) AR246965A1 (he)
AT (1) ATE109478T1 (he)
AU (1) AU626534B2 (he)
CA (1) CA1335816C (he)
DE (1) DE68917170T2 (he)
DK (1) DK66989A (he)
ES (1) ES2057104T3 (he)
FI (1) FI93216C (he)
GB (1) GB8901201D0 (he)
HU (1) HU209700B (he)
IE (1) IE63825B1 (he)
IL (1) IL89214A (he)
MY (1) MY103699A (he)
NO (1) NO172491C (he)
NZ (1) NZ227880A (he)
PH (1) PH26227A (he)
PL (1) PL158201B1 (he)
PT (1) PT89703B (he)
ZW (1) ZW1789A1 (he)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
WO2007138485A2 (en) * 2006-01-18 2007-12-06 Evolva Sa Ppar modulators
JP5662682B2 (ja) * 2007-01-18 2015-02-04 エヴォルヴァ エスアー Ｐｐａｒモジュレータとして有用な置換１，３−ジオキサン
WO2008089463A2 (en) * 2007-01-18 2008-07-24 Evolva Sa Substituted 1,3-dioxanes and their uses

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3262096D1 (en) * 1981-03-30 1985-03-14 Hoffmann La Roche 1,3-dioxolane derivatives, their preparation, fungicidal agents containing those compounds as active agents and use of such compounds or agents in combating fungi in agriculture and in gardening
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8330099D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cycloalkane derivatives
GB8330094D0 (en) * 1983-11-11 1983-12-21 Ici Plc Diphenyl compounds
GB8330120D0 (en) * 1983-11-11 1983-12-21 Ici Plc Chemical process
US4554011A (en) * 1984-08-24 1985-11-19 Chevron Research Company Herbicidal 2S-(2β,4β,5β)-5-Arylmethoxy-4-substituted 2-alkyl-1,3-dioxane derivatives
GB8511890D0 (en) * 1985-05-10 1985-06-19 Ici Plc Benzene derivatives
ES8802508A1 (es) * 1985-05-10 1988-07-16 Ici Plc Procedimiento para preparar derivados alquenicos.
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
GB8511892D0 (en) * 1985-05-10 1985-06-19 Ici Plc Fluoralkane derivatives
GB8511894D0 (en) * 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
DK212786A (da) * 1985-05-10 1986-11-11 Ici Plc 1,3-dioxanethere
EP0223518B1 (en) * 1985-11-12 1990-09-26 Imperial Chemical Industries Plc Amide derivatives
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
GB8531892D0 (en) * 1985-12-30 1986-02-05 Ici Plc Carboxylic acids
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives

Also Published As

Publication number Publication date
MY103699A (en) 1993-08-28
EP0329360A2 (en) 1989-08-23
FI93216B (fi) 1994-11-30
PT89703A (pt) 1989-10-04
GB8901201D0 (en) 1989-03-15
IE890392L (en) 1989-08-16
NO890607L (no) 1989-08-17
CA1335816C (en) 1995-06-06
FI890678A0 (fi) 1989-02-13
ZW1789A1 (en) 1990-03-21
ATE109478T1 (de) 1994-08-15
NO172491C (no) 1993-07-28
NO890607D0 (no) 1989-02-13
DE68917170T2 (de) 1994-12-15
AU2990889A (en) 1989-08-17
FI93216C (fi) 1995-03-10
PT89703B (pt) 1994-04-29
AU626534B2 (en) 1992-08-06
EP0329360A3 (en) 1990-09-05
DK66989A (da) 1989-08-17
KR0145725B1 (ko) 1998-08-17
US5166213A (en) 1992-11-24
DK66989D0 (da) 1989-02-13
NZ227880A (en) 1991-10-25
KR890013005A (ko) 1989-09-20
FI890678A (fi) 1989-08-17
HUT54143A (en) 1991-01-28
HU209700B (en) 1994-10-28
AR246965A1 (es) 1994-10-31
CN1035115A (zh) 1989-08-30
ES2057104T3 (es) 1994-10-16
IE63825B1 (en) 1995-06-14
JPH01249770A (ja) 1989-10-05
PL158201B1 (pl) 1992-08-31
CN1040753C (zh) 1998-11-18
EP0329360B1 (en) 1994-08-03
PH26227A (en) 1992-04-01
JP2812697B2 (ja) 1998-10-22
NO172491B (no) 1993-04-19
DE68917170D1 (de) 1994-09-08

Similar Documents

Publication Publication Date Title
US5053415A (en) Pyridine derivatives
CA1335816C (en) 4-pyridyl-1,3-dioxan-5-ylalkenoic acid derivatives
JP2620298B2 (ja) １，３‐ジオキサンアルカノイツク酸誘導体、その製法、これを含有する心臓及び血管の疾病の治療剤及び中間体
US4908380A (en) Pharmaceutical compositions
US5248780A (en) Pyridyl substituted alkenoic acid derivatives
US4925869A (en) Therapeutic agents
KR100191763B1 (ko) 헤테로시클릭산
RU2040525C1 (ru) 1,3-дииоксаноновые производные алкеновой кислоты или их фармацевтически приемлемая соль
EP0201351A2 (en) 1,3-Dioxane ethers

Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force