IL87662A0 - Pharmaceutical compositions containing 2-alkoxy-n-(1-azabi-cyclo(2.2.2)oct-3-yl)-benzamides and thiobenzamides - Google Patents
Pharmaceutical compositions containing 2-alkoxy-n-(1-azabi-cyclo(2.2.2)oct-3-yl)-benzamides and thiobenzamidesInfo
- Publication number
- IL87662A0 IL87662A0 IL87662A IL8766288A IL87662A0 IL 87662 A0 IL87662 A0 IL 87662A0 IL 87662 A IL87662 A IL 87662A IL 8766288 A IL8766288 A IL 8766288A IL 87662 A0 IL87662 A0 IL 87662A0
- Authority
- IL
- Israel
- Prior art keywords
- alkoxy
- thiobenzamides
- benzamides
- oct
- azabi
- Prior art date
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- -1 amino, methylamino Chemical group 0.000 abstract 1
- 230000002932 anti-schizophrenic effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000003936 benzamides Chemical class 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878720805A GB8720805D0 (en) | 1987-09-04 | 1987-09-04 | 2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL87662A0 true IL87662A0 (en) | 1989-02-28 |
Family
ID=10623261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL87662A IL87662A0 (en) | 1987-09-04 | 1988-09-02 | Pharmaceutical compositions containing 2-alkoxy-n-(1-azabi-cyclo(2.2.2)oct-3-yl)-benzamides and thiobenzamides |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4877794A (fr) |
| EP (1) | EP0306345B1 (fr) |
| JP (1) | JPH0269417A (fr) |
| AT (1) | ATE88091T1 (fr) |
| AU (1) | AU614768B2 (fr) |
| CA (1) | CA1318595C (fr) |
| DE (1) | DE3880240T2 (fr) |
| DK (1) | DK492688A (fr) |
| GB (1) | GB8720805D0 (fr) |
| IL (1) | IL87662A0 (fr) |
| PH (1) | PH25429A (fr) |
| ZA (1) | ZA886586B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0353372B1 (fr) * | 1988-08-04 | 1993-02-03 | Synthelabo | S-N-(1-azabicyclo [2.2.2.]oct-3-yl)benzamides et thiobenzamides ayant une activité antischizophrénique |
| AU631632B2 (en) * | 1989-04-21 | 1992-12-03 | Novartis Ag | Therapeutic use of 5-ht3 receptor antagonists |
| US5236931A (en) * | 1992-03-26 | 1993-08-17 | A. H. Robins Company, Incorporated | 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol |
| WO2002016357A2 (fr) | 2000-08-18 | 2002-02-28 | Pharmacia & Upjohn Company | Composes aryle substitues par quinuclidine destines au traitement de maladies |
| AU2001282874A1 (en) | 2000-08-18 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
| MXPA04000779A (es) * | 2001-08-24 | 2004-04-20 | Pharmacia & Up John Company | 7-aza[2.2.1]bicicloheptanos sustituidos con arilo para el tratamiento de enfermedades. |
| MXPA04007936A (es) | 2002-02-15 | 2004-11-26 | Upjohn Co | Compuestos de aril-sustituidos para el tratamiento de enfermedades. |
| MXPA04007083A (es) * | 2002-02-20 | 2004-10-29 | Upjohn Co | Compuestos azabiciclicos para el tratamiento de enfermedades. |
| FR2861076B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
| JP5775819B2 (ja) | 2008-10-09 | 2015-09-09 | ハワード ヒューズ メディカル インスティチュート | 新規なキメラリガンド開口型イオンチャネルおよびその使用方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4093734A (en) * | 1975-11-03 | 1978-06-06 | Boehringer Ingelheim Gmbh | Amino-benzoic acid amides |
| FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
| FR2529548A1 (fr) * | 1982-07-02 | 1984-01-06 | Delalande Sa | Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique |
| US4593034A (en) * | 1984-04-06 | 1986-06-03 | A. H. Robins Company, Inc. | 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides |
| US4605652A (en) * | 1985-02-04 | 1986-08-12 | A. H. Robins Company, Inc. | Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes |
| DE3689974T2 (de) * | 1985-03-14 | 1994-11-03 | Beecham Group Plc | Arzneimittel zur Behandlung von Emesis. |
| GB8511988D0 (en) * | 1985-05-11 | 1985-06-19 | Beecham Group Plc | Compounds |
| EP0272052B1 (fr) * | 1986-12-16 | 1992-07-08 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | N-(1-Azabicyclo[2.2.2]oct-3-yl)benzamides et -thiobenzamides anxiolytiques |
-
1987
- 1987-09-04 GB GB878720805A patent/GB8720805D0/en active Pending
-
1988
- 1988-09-02 IL IL87662A patent/IL87662A0/xx unknown
- 1988-09-05 DE DE88308182T patent/DE3880240T2/de not_active Expired - Fee Related
- 1988-09-05 JP JP63220559A patent/JPH0269417A/ja active Pending
- 1988-09-05 DK DK492688A patent/DK492688A/da not_active Application Discontinuation
- 1988-09-05 AT AT88308182T patent/ATE88091T1/de not_active IP Right Cessation
- 1988-09-05 PH PH37505A patent/PH25429A/en unknown
- 1988-09-05 AU AU21834/88A patent/AU614768B2/en not_active Ceased
- 1988-09-05 EP EP88308182A patent/EP0306345B1/fr not_active Expired - Lifetime
- 1988-09-05 ZA ZA886586A patent/ZA886586B/xx unknown
- 1988-09-06 US US07/240,868 patent/US4877794A/en not_active Expired - Fee Related
- 1988-09-06 CA CA000576593A patent/CA1318595C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0306345B1 (fr) | 1993-04-14 |
| DE3880240T2 (de) | 1993-10-28 |
| ATE88091T1 (de) | 1993-04-15 |
| US4877794A (en) | 1989-10-31 |
| EP0306345A2 (fr) | 1989-03-08 |
| DE3880240D1 (de) | 1993-05-19 |
| CA1318595C (fr) | 1993-06-01 |
| AU614768B2 (en) | 1991-09-12 |
| GB8720805D0 (en) | 1987-10-14 |
| AU2183488A (en) | 1989-03-09 |
| JPH0269417A (ja) | 1990-03-08 |
| ZA886586B (en) | 1990-05-30 |
| DK492688A (da) | 1989-03-05 |
| DK492688D0 (da) | 1988-09-05 |
| EP0306345A3 (en) | 1989-06-14 |
| PH25429A (en) | 1991-07-01 |
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