IL87172A - A method of inhibiting the isolation of a purer tissue factor - Google Patents

A method of inhibiting the isolation of a purer tissue factor

Info

Publication number
IL87172A
IL87172A IL8717288A IL8717288A IL87172A IL 87172 A IL87172 A IL 87172A IL 8717288 A IL8717288 A IL 8717288A IL 8717288 A IL8717288 A IL 8717288A IL 87172 A IL87172 A IL 87172A
Authority
IL
Israel
Prior art keywords
tfi
factor
column
activity
purified
Prior art date
Application number
IL8717288A
Other languages
English (en)
Hebrew (he)
Other versions
IL87172A0 (en
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22137642&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL87172(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Washington filed Critical Univ Washington
Publication of IL87172A0 publication Critical patent/IL87172A0/xx
Publication of IL87172A publication Critical patent/IL87172A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL8717288A 1987-07-23 1988-07-21 A method of inhibiting the isolation of a purer tissue factor IL87172A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7736687A 1987-07-23 1987-07-23

Publications (2)

Publication Number Publication Date
IL87172A0 IL87172A0 (en) 1988-12-30
IL87172A true IL87172A (en) 1994-12-29

Family

ID=22137642

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8717288A IL87172A (en) 1987-07-23 1988-07-21 A method of inhibiting the isolation of a purer tissue factor

Country Status (14)

Country Link
US (3) US6534276B1 (xx)
EP (1) EP0300988A3 (xx)
JP (1) JP2781391B2 (xx)
KR (1) KR900007261B1 (xx)
AU (1) AU604138B2 (xx)
BR (1) BR1100464A (xx)
CA (1) CA1338122C (xx)
DK (1) DK174522B1 (xx)
FI (1) FI97298C (xx)
IL (1) IL87172A (xx)
NO (1) NO174776C (xx)
NZ (1) NZ225534A (xx)
PT (1) PT88075B (xx)
ZA (2) ZA885370B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87171A (en) * 1987-11-23 1995-08-31 Monsanto Co ANDC of human tissue factor inhibitor
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
US5378614A (en) * 1989-08-18 1995-01-03 Novo Nordisk A/S Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast
PT98779B (pt) * 1990-08-27 1999-06-30 Monsanto Co Processo para a preparacao de uma composicao anticoagulante contendo inibidor sulfatados e metodos para a sua utilizacao
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
US5346991A (en) * 1991-06-13 1994-09-13 Genentech, Inc. Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders
US5276015A (en) * 1992-03-18 1994-01-04 Washington University Method of inhibiting microvascular thrombosis
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
KR100443572B1 (ko) * 2002-05-29 2004-08-09 광양청매실농원영농조합법인 매실 농축액 제조방법
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
EP2298278B1 (en) * 2002-06-07 2015-11-11 Dyax Corp. Prevention and reduction of blood loss and inflammatory response
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US8828703B2 (en) 2005-12-29 2014-09-09 Dyax Corp. Protease inhibition
WO2007092607A2 (en) * 2006-02-09 2007-08-16 Genetech, Inc. Treatment of hemorrhagic viral infections using a tissue factor inhibitor
US20090075887A1 (en) * 2007-08-21 2009-03-19 Genzyme Corporation Treatment with Kallikrein Inhibitors
JP5580205B2 (ja) * 2007-11-19 2014-08-27 セレラ コーポレーション 肺癌マーカーとその使用
AU2010203712A1 (en) 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
RS62853B1 (sr) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Proteini koji vezuju kalikrein plazme
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
CN106459210A (zh) 2014-03-27 2017-02-22 戴埃克斯有限公司 用于治疗糖尿病黄斑性水肿的组合物和方法
US11286307B2 (en) 2015-12-11 2022-03-29 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE81149B1 (en) * 1987-02-12 2000-05-03 Genentech Inc Methods and deoxyribonucleic acid for the preparation of tissue factor protein
US5223427A (en) * 1987-03-31 1993-06-29 The Scripps Research Institute Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain
AU1948388A (en) * 1987-06-12 1989-01-04 Mount Sinai School Of Medicine Of The City University Of New York, The Cloning and expression of human tissue factor
US4966852A (en) * 1987-07-23 1990-10-30 Monsanto Company DNA clone of human tissue factor inhibitor

Also Published As

Publication number Publication date
CA1338122C (en) 1996-03-05
FI883477A (fi) 1989-01-24
FI97298C (fi) 1996-11-25
US6534276B1 (en) 2003-03-18
PT88075A (pt) 1989-07-31
FI883477A0 (fi) 1988-07-22
US7060805B2 (en) 2006-06-13
DK174522B1 (da) 2003-05-12
US20030166194A1 (en) 2003-09-04
NZ225534A (en) 1991-02-26
ZA885371B (en) 1989-04-26
EP0300988A3 (en) 1990-04-11
AU1928688A (en) 1989-02-02
ZA885370B (en) 1989-10-25
NO174776C (no) 1994-07-06
EP0300988A2 (en) 1989-01-25
IL87172A0 (en) 1988-12-30
NO174776B (no) 1994-03-28
NO883271L (no) 1989-01-24
JPS6447799A (en) 1989-02-22
DK413588D0 (da) 1988-07-22
NO883271D0 (no) 1988-07-22
AU604138B2 (en) 1990-12-06
US6806360B2 (en) 2004-10-19
DK413588A (da) 1989-01-24
JP2781391B2 (ja) 1998-07-30
PT88075B (pt) 1995-06-30
US20040265981A1 (en) 2004-12-30
KR900007261B1 (en) 1990-10-06
BR1100464A (pt) 2000-02-08
FI97298B (fi) 1996-08-15
KR890001581A (ko) 1989-03-27

Similar Documents

Publication Publication Date Title
CA1338122C (en) Tissue factor inhibitor of coagulation
Broze Jr et al. Isolation of the tissue factor inhibitor produced by HepG2 hepatoma cells.
US5466783A (en) Human tissue factor inhibitor
US4245051A (en) Human serum plasminogen activator
JP3122127B2 (ja) 抗凝血タンパク質
EP0197901B1 (en) Biologically active fragments of the human antihemophilic factor and method for their preparation and pharmaceutical preparations
AU2002218306A1 (en) Von willebrand factor (vWF) cleaving protease polypeptide, nucleic acid encoding the polypeptide and use of polypeptide
EP0182372A2 (en) New factor VIII coagulant polypeptides
JPH01165383A (ja) ヒト組織因子抑制因子のdnaクローン
JPH0443638B2 (xx)
EP0439442B1 (en) Factor x-laci hybrid protein
JPH08500833A (ja) 凝血性蛋白質に特異的な抗体、未変性蛋白質を単離するためのそれらの利用、その蛋白質の蛋白質分解性開裂産物を含まない凝血性組成物
US4886876A (en) Factor VIII coagulant polypeptides
Franco et al. Synthesis and apparent secretion of prothymosin alpha by different subpopulations of calf and rat thymocytes.
DE3486023T2 (de) Verfahren zur herstellung von urokinase zymogen.
JPH08510212A (ja) 鉤虫抗凝固剤
OHLSSON et al. Monoclonal Antibodies Specific for Neutrophil Proteinase 4. Production and Use for Isolation of the Enyzme
He et al. Rabbit plasma, unlike its human counterpart, contains no complex between protein S and C4b-binding protein
EP0380443A2 (en) Monoclonal antibodies specific for thrombin hirudin
JP3022984B2 (ja) 細菌コラゲナーゼ遺伝子
Mezina et al. Isolation of milk-clotting enzyme from transgenic sheep milk and its comparison with calf chymosin
EP0354408A1 (en) Anti-urokinase monoclonal antibodies
JPH11508449A (ja) 組換えヒト前立腺特異的抗原およびその使用
IE911285A1 (en) Monoclonal antibodies against PP4, processes for the¹preparation thereof and the use thereof
Yamamoto et al. Presence of active and inactive molecules of a cell wall-associated proteinase in Lactobacillus helveticus CP790

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired