IL87172A - A method of inhibiting the isolation of a purer tissue factor - Google Patents

A method of inhibiting the isolation of a purer tissue factor

Info

Publication number
IL87172A
IL87172A IL8717288A IL8717288A IL87172A IL 87172 A IL87172 A IL 87172A IL 8717288 A IL8717288 A IL 8717288A IL 8717288 A IL8717288 A IL 8717288A IL 87172 A IL87172 A IL 87172A
Authority
IL
Israel
Prior art keywords
tfi
factor
column
activity
purified
Prior art date
Application number
IL8717288A
Other languages
English (en)
Hebrew (he)
Other versions
IL87172A0 (en
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22137642&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL87172(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Washington filed Critical Univ Washington
Publication of IL87172A0 publication Critical patent/IL87172A0/xx
Publication of IL87172A publication Critical patent/IL87172A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL8717288A 1987-07-23 1988-07-21 A method of inhibiting the isolation of a purer tissue factor IL87172A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7736687A 1987-07-23 1987-07-23

Publications (2)

Publication Number Publication Date
IL87172A0 IL87172A0 (en) 1988-12-30
IL87172A true IL87172A (en) 1994-12-29

Family

ID=22137642

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8717288A IL87172A (en) 1987-07-23 1988-07-21 A method of inhibiting the isolation of a purer tissue factor

Country Status (14)

Country Link
US (3) US6534276B1 (fr)
EP (1) EP0300988A3 (fr)
JP (1) JP2781391B2 (fr)
KR (1) KR900007261B1 (fr)
AU (1) AU604138B2 (fr)
BR (1) BR1100464A (fr)
CA (1) CA1338122C (fr)
DK (1) DK174522B1 (fr)
FI (1) FI97298C (fr)
IL (1) IL87172A (fr)
NO (1) NO174776C (fr)
NZ (1) NZ225534A (fr)
PT (1) PT88075B (fr)
ZA (2) ZA885370B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87171A (en) * 1987-11-23 1995-08-31 Monsanto Co ANDC of human tissue factor inhibitor
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
US5378614A (en) * 1989-08-18 1995-01-03 Novo Nordisk A/S Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast
PT98779B (pt) * 1990-08-27 1999-06-30 Monsanto Co Processo para a preparacao de uma composicao anticoagulante contendo inibidor sulfatados e metodos para a sua utilizacao
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
US5346991A (en) * 1991-06-13 1994-09-13 Genentech, Inc. Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders
US5276015A (en) * 1992-03-18 1994-01-04 Washington University Method of inhibiting microvascular thrombosis
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
KR100443572B1 (ko) * 2002-05-29 2004-08-09 광양청매실농원영농조합법인 매실 농축액 제조방법
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
DK2311432T3 (en) * 2002-06-07 2015-02-02 Dyax Corp Modified Kunitz domain polypeptides and their use in reducing ischemia or the onset of a systemic inflammatory response associated with a surgical procedure
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
DK1981519T3 (en) 2005-12-29 2018-02-19 Dyax Corp protease inhibition
WO2007092607A2 (fr) * 2006-02-09 2007-08-16 Genetech, Inc. Traitement d'infections virales hémorragiques au moyen d'un inhibiteur du facteur tissulaire
WO2009026334A2 (fr) * 2007-08-21 2009-02-26 Genzyme Corporation Traitement par des inhibiteurs de la kallikréine
EP2728017B1 (fr) * 2007-11-19 2016-08-24 Celera Corporation Marqueurs du cancer du poumon et utilisations de ceux-ci
US8637454B2 (en) 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
ES2905545T3 (es) 2010-01-06 2022-04-11 Takeda Pharmaceuticals Co Proteínas de unión a calicreína plasmática
KR102502293B1 (ko) 2011-01-06 2023-02-21 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 결합 단백질
CA2942713A1 (fr) 2014-03-27 2015-10-01 Dyax Corp. Compositions et procedes pour le traitement de l'oedeme maculaire diabetique
EA201891388A1 (ru) 2015-12-11 2018-11-30 Дайэкс Корп. Ингибиторы калликреина плазмы и их применение для лечения обострения наследственного ангионевротического отека

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE81149B1 (en) * 1987-02-12 2000-05-03 Genentech Inc Methods and deoxyribonucleic acid for the preparation of tissue factor protein
US5223427A (en) * 1987-03-31 1993-06-29 The Scripps Research Institute Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain
AU1948388A (en) * 1987-06-12 1989-01-04 Mount Sinai School Of Medicine Of The City University Of New York, The Cloning and expression of human tissue factor
US4966852A (en) * 1987-07-23 1990-10-30 Monsanto Company DNA clone of human tissue factor inhibitor

Also Published As

Publication number Publication date
NO883271D0 (no) 1988-07-22
KR890001581A (ko) 1989-03-27
DK413588A (da) 1989-01-24
FI883477A0 (fi) 1988-07-22
BR1100464A (pt) 2000-02-08
ZA885371B (en) 1989-04-26
DK413588D0 (da) 1988-07-22
CA1338122C (fr) 1996-03-05
NO174776B (no) 1994-03-28
AU1928688A (en) 1989-02-02
NZ225534A (en) 1991-02-26
EP0300988A3 (fr) 1990-04-11
US7060805B2 (en) 2006-06-13
FI97298C (fi) 1996-11-25
FI97298B (fi) 1996-08-15
ZA885370B (en) 1989-10-25
PT88075B (pt) 1995-06-30
JPS6447799A (en) 1989-02-22
PT88075A (pt) 1989-07-31
KR900007261B1 (en) 1990-10-06
US6806360B2 (en) 2004-10-19
JP2781391B2 (ja) 1998-07-30
DK174522B1 (da) 2003-05-12
US6534276B1 (en) 2003-03-18
US20030166194A1 (en) 2003-09-04
NO883271L (no) 1989-01-24
AU604138B2 (en) 1990-12-06
EP0300988A2 (fr) 1989-01-25
IL87172A0 (en) 1988-12-30
FI883477A (fi) 1989-01-24
NO174776C (no) 1994-07-06
US20040265981A1 (en) 2004-12-30

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