IL86395A - Pharmaceutical compositions with improved bioavailability containing flunarizine and polyethoxylated castor oil - Google Patents
Pharmaceutical compositions with improved bioavailability containing flunarizine and polyethoxylated castor oilInfo
- Publication number
- IL86395A IL86395A IL86395A IL8639588A IL86395A IL 86395 A IL86395 A IL 86395A IL 86395 A IL86395 A IL 86395A IL 8639588 A IL8639588 A IL 8639588A IL 86395 A IL86395 A IL 86395A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- castor oil
- improved bioavailability
- polyethoxylated castor
- flunarizine
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5064487A | 1987-05-18 | 1987-05-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL86395A0 IL86395A0 (en) | 1988-11-15 |
| IL86395A true IL86395A (en) | 1992-11-15 |
Family
ID=21966482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL86395A IL86395A (en) | 1987-05-18 | 1988-05-16 | Pharmaceutical compositions with improved bioavailability containing flunarizine and polyethoxylated castor oil |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0292050B1 (no) |
| JP (1) | JPS63303926A (no) |
| KR (1) | KR880013559A (no) |
| AT (1) | ATE69555T1 (no) |
| AU (1) | AU603895B2 (no) |
| DE (1) | DE3866281D1 (no) |
| DK (1) | DK268788A (no) |
| ES (1) | ES2051827T3 (no) |
| FI (1) | FI882307A (no) |
| GR (1) | GR3003482T3 (no) |
| HU (1) | HU199073B (no) |
| IE (1) | IE60937B1 (no) |
| IL (1) | IL86395A (no) |
| NO (1) | NO882134L (no) |
| NZ (1) | NZ224497A (no) |
| PH (1) | PH24425A (no) |
| PT (1) | PT87496B (no) |
| RU (1) | RU1829935C (no) |
| ZA (1) | ZA883492B (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5532002A (en) * | 1989-08-17 | 1996-07-02 | Cortecs Limited | Gelatin pharmaceutical formulations |
| DK0487575T3 (da) * | 1989-08-17 | 1994-11-28 | Cortecs Ltd | Farmaceutiske formuleringer |
| NZ258044A (en) * | 1992-11-27 | 1995-12-21 | Faulding F H & Co Ltd | Pharmaceutical composition comprising taxol, solubilising agent, an acid and an organic solvent |
| TW401300B (en) * | 1992-12-25 | 2000-08-11 | Senju Pharma Co | Antiallergic composition for ophthalmic or nasal use |
| FR2729307B1 (fr) * | 1995-01-18 | 1997-04-18 | Seppic Sa | Utilisation d'esters d'acides gras ethoxyles comme composants auto-emulsionnables notamment utiles pour la preparation de produits de traitement phytosanitaires ou de medicaments a usage veterinaire ou humain |
| US6596706B1 (en) * | 1997-11-07 | 2003-07-22 | Daiichi Pharmaceutical Co., Ltd. | Piperazine-cyclodextrin complexes |
| US6683100B2 (en) | 1999-01-19 | 2004-01-27 | Novartis Ag | Organic compounds |
| US6194181B1 (en) | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
| DE60234952D1 (de) * | 2001-09-10 | 2010-02-11 | Tibotec Pharm Ltd | VERFAHREN ZUR HERSTELLUNG VON HEXAHYDROFUROc2,3-BÜFURAN-3-OL |
| AR038681A1 (es) * | 2002-02-14 | 2005-01-26 | Solvay Pharm Bv | Formulacion oral de solucion solida de una sustancia activa pobremente soluble en agua |
| WO2004062692A1 (en) * | 2003-01-13 | 2004-07-29 | Solvay Pharmaceuticals B.V. | Formulation of poorly water-soluble active substances |
| WO2011047259A1 (en) | 2009-10-16 | 2011-04-21 | Glaxosmithkline Llc | Compositions |
| CN104069086A (zh) * | 2014-07-22 | 2014-10-01 | 周有财 | 一种盐酸氟桂利嗪组合物胶囊及其制备方法 |
| CN113262207B (zh) * | 2020-02-17 | 2022-06-17 | 正大青春宝药业有限公司 | 一种盐酸氟桂利嗪胶囊制剂及其制备方法 |
| CN115381791B (zh) * | 2022-09-21 | 2023-06-16 | 迪沙药业集团有限公司 | 一种盐酸氟桂利嗪药物组合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346123A1 (de) * | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| EP0151987B1 (de) * | 1984-01-28 | 1991-05-29 | Roshdy Dr. Ismail | Mittel zur Behandlung von Erkrankungen der Venen und des Analbereichs |
| DE3421468A1 (de) * | 1984-06-08 | 1985-12-19 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung |
| GB8506792D0 (en) * | 1985-03-15 | 1985-04-17 | Janssen Pharmaceutica Nv | Derivatives of y-cyclodextrin |
| US5047229A (en) * | 1986-12-17 | 1991-09-10 | Miles, Inc. | Treatment of cardiovascular and cerebral toxicity using calcium modulators |
-
1988
- 1988-05-04 NZ NZ224497A patent/NZ224497A/en unknown
- 1988-05-10 AT AT88200931T patent/ATE69555T1/de not_active IP Right Cessation
- 1988-05-10 DE DE8888200931T patent/DE3866281D1/de not_active Expired - Fee Related
- 1988-05-10 EP EP88200931A patent/EP0292050B1/en not_active Expired - Lifetime
- 1988-05-10 ES ES88200931T patent/ES2051827T3/es not_active Expired - Lifetime
- 1988-05-13 AU AU16132/88A patent/AU603895B2/en not_active Ceased
- 1988-05-16 NO NO882134A patent/NO882134L/no unknown
- 1988-05-16 JP JP63117160A patent/JPS63303926A/ja active Pending
- 1988-05-16 IL IL86395A patent/IL86395A/xx unknown
- 1988-05-17 KR KR1019880005737A patent/KR880013559A/ko not_active Application Discontinuation
- 1988-05-17 IE IE147788A patent/IE60937B1/en not_active IP Right Cessation
- 1988-05-17 HU HU882453A patent/HU199073B/hu not_active IP Right Cessation
- 1988-05-17 PT PT87496A patent/PT87496B/pt not_active IP Right Cessation
- 1988-05-17 RU SU884355695A patent/RU1829935C/ru active
- 1988-05-17 DK DK268788A patent/DK268788A/da not_active Application Discontinuation
- 1988-05-17 ZA ZA883492A patent/ZA883492B/xx unknown
- 1988-05-17 FI FI882307A patent/FI882307A/fi not_active Application Discontinuation
- 1988-05-23 PH PH36962A patent/PH24425A/en unknown
-
1991
- 1991-12-31 GR GR91402259T patent/GR3003482T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3866281D1 (de) | 1992-01-02 |
| PT87496B (pt) | 1992-09-30 |
| DK268788A (da) | 1988-11-19 |
| AU1613288A (en) | 1988-11-24 |
| KR880013559A (ko) | 1988-12-21 |
| ES2051827T3 (es) | 1994-07-01 |
| IE60937B1 (en) | 1994-09-07 |
| HUT46851A (en) | 1988-12-28 |
| PH24425A (en) | 1990-06-25 |
| HU199073B (en) | 1990-01-29 |
| GR3003482T3 (en) | 1993-02-17 |
| FI882307A0 (fi) | 1988-05-17 |
| IE881477L (en) | 1988-11-18 |
| NO882134D0 (no) | 1988-05-16 |
| PT87496A (pt) | 1989-05-31 |
| EP0292050B1 (en) | 1991-11-21 |
| IL86395A0 (en) | 1988-11-15 |
| ZA883492B (en) | 1990-01-31 |
| JPS63303926A (ja) | 1988-12-12 |
| RU1829935C (ru) | 1993-07-23 |
| DK268788D0 (da) | 1988-05-17 |
| NO882134L (no) | 1988-11-21 |
| AU603895B2 (en) | 1990-11-29 |
| ATE69555T1 (de) | 1991-12-15 |
| NZ224497A (en) | 1990-04-26 |
| EP0292050A1 (en) | 1988-11-23 |
| FI882307A (fi) | 1988-11-19 |
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