IL85870A - Controlled release pharmaceutical compositions for oral administration containing 3'-azido-3'-deoxythymidine - Google Patents

Controlled release pharmaceutical compositions for oral administration containing 3'-azido-3'-deoxythymidine

Info

Publication number
IL85870A
IL85870A IL85870A IL8587088A IL85870A IL 85870 A IL85870 A IL 85870A IL 85870 A IL85870 A IL 85870A IL 8587088 A IL8587088 A IL 8587088A IL 85870 A IL85870 A IL 85870A
Authority
IL
Israel
Prior art keywords
controlled release
deoxythymidine
azido
pharmaceutical compositions
oral administration
Prior art date
Application number
IL85870A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL85870A publication Critical patent/IL85870A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL85870A 1987-03-27 1988-03-25 Controlled release pharmaceutical compositions for oral administration containing 3'-azido-3'-deoxythymidine IL85870A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878707421A GB8707421D0 (en) 1987-03-27 1987-03-27 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
IL85870A true IL85870A (en) 1992-02-16

Family

ID=10614823

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85870A IL85870A (en) 1987-03-27 1988-03-25 Controlled release pharmaceutical compositions for oral administration containing 3'-azido-3'-deoxythymidine

Country Status (17)

Country Link
US (1) US4917900A (es)
EP (1) EP0284407B1 (es)
JP (1) JP2719344B2 (es)
KR (1) KR960013434B1 (es)
AT (1) ATE63818T1 (es)
AU (1) AU607474B2 (es)
CA (1) CA1308026C (es)
DE (1) DE3862974D1 (es)
DK (1) DK175348B1 (es)
ES (1) ES2033426T3 (es)
GB (1) GB8707421D0 (es)
GR (1) GR3002030T3 (es)
IE (1) IE60605B1 (es)
IL (1) IL85870A (es)
NZ (1) NZ224026A (es)
PT (1) PT87081B (es)
ZA (1) ZA882168B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051361A (en) * 1988-10-19 1991-09-24 Sigma Chemical Company AZT immunoassays, derivatives, conjugates and antibodies
US4938966A (en) * 1988-11-30 1990-07-03 Riker Laboratories, Inc. Controlled release flecainide acetate formulation
GB8912420D0 (en) 1989-05-31 1989-07-19 Schram Cornelius J Ultrasonic systems
EP0452862B1 (en) * 1990-04-18 1995-07-19 Asahi Kasei Kogyo Kabushiki Kaisha Spherical seed cores, spherical granules and process for production thereof
US5102668A (en) * 1990-10-05 1992-04-07 Kingaform Technology, Inc. Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH
HUT63852A (en) * 1991-06-21 1993-10-28 Acic Canada Inc Process for producing antiviral compounds and pharmaceutical compositions comprising same as active ingredient
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
EP0654038B1 (en) * 1992-08-04 1999-11-10 James M. Dunn Controlled release pharmaceutical formulations of 3'-azido-3'-deoxythymidine and methods of use
FR2698560B1 (fr) * 1992-11-30 1995-02-03 Virbac Laboratoires Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications.
US6245351B1 (en) 1996-03-07 2001-06-12 Takeda Chemical Industries, Ltd. Controlled-release composition
DE19945982A1 (de) * 1999-09-24 2001-03-29 Knoll Ag Geschwindigkeitsbestimmte Partikel
WO2001045676A2 (en) 1999-12-20 2001-06-28 Schering Corporation Extended release oral dosage composition
WO2001045668A2 (en) * 1999-12-20 2001-06-28 Schering Corporation Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine
PL366089A1 (en) * 2000-03-30 2005-01-24 Bristol-Myers Squibb Company Sustained release beadlets containing stavudine
JP4390702B2 (ja) * 2002-06-24 2009-12-24 株式会社Ａｄｅｋａ 難燃剤組成物及び該組成物を含有した難燃性樹脂組成物
WO2004043433A2 (en) * 2002-11-08 2004-05-27 Glaxo Group Limited Pharmaceutical antiviral compositions
WO2005048978A2 (en) * 2003-10-01 2005-06-02 Lupin Limited A controlled release pharmaceutical composition and a process for preparing the same
GB0403247D0 (en) 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
EP1730516A1 (en) * 2004-03-30 2006-12-13 Pfizer Products Incorporated Method and device for evaluation of pharmaceutical compositions
WO2008065502A1 (en) * 2006-11-29 2008-06-05 Pfizer Products Inc. Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein
WO2008125940A2 (en) * 2007-04-17 2008-10-23 Pfizer Products Inc. Nanoparticles comprising non-crystalline drug
WO2008135828A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US20100080852A1 (en) * 2007-05-03 2010-04-01 Ronald Arthur Beyerinck Phamaceutical composition comprising nanoparticles and casein
EP2162120B1 (en) * 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2178518A2 (en) * 2007-07-13 2010-04-28 Bend Research, Inc Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers
WO2009073215A1 (en) * 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US9233078B2 (en) * 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
US20140271893A1 (en) * 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Coated phenylephrine particles and use thereof in pharmaceutical formulations
CN106333957A (zh) * 2016-08-19 2017-01-18 丁静 齐多夫定用于制备自身免疫性神经炎治疗药物的应用
FR3070390A1 (fr) * 2017-08-25 2019-03-01 Eleonor Composition comprenant au moins un alcaloide de protoberberine et son procede de fabrication

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE145365C (es) *
BE785702A (fr) * 1971-07-14 1972-10-16 Roehm Gmbh Produits de revetement de formes medicamenteuses et leur utilisation
BE787973A (fr) * 1971-09-04 1973-02-26 Beecham Group Ltd Comprimes pharmaceutiques a effet retard
ES438635A1 (es) * 1974-06-24 1977-02-16 Shinetsu Chemical Co Procedimiento para el revestimiento de moldes solidos de do-sificacion.
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
ATE13486T1 (de) * 1980-11-12 1985-06-15 Ciba Geigy Ag Schnellzerfallende arzneimittel-presslinge.
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
DE3126703A1 (de) * 1981-07-07 1983-01-27 Dr. Karl Thomae Gmbh, 7950 Biberach Bromhexin-retardform und verfahren zu ihrer herstellung
ZA825384B (en) * 1981-07-31 1983-05-25 Tillott J B Ltd Orally administrable pharmaceutical compositions
IT1168014B (it) * 1981-08-05 1987-05-20 Erba Farmitalia Forme farmaceutiche a cessione protratta
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
JPS59193831A (ja) * 1983-04-18 1984-11-02 Sankyo Co Ltd 腸溶性製剤の製造法
JPS59227817A (ja) * 1983-06-07 1984-12-21 Toyo Jozo Co Ltd 持続性経口用ブレデニン製剤
JPH075457B2 (ja) * 1983-08-16 1995-01-25 ザ ウエルカム フアウンデ−シヨン リミテツド 調節された方法による有効成分の放出を可能にする医薬組成物
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
GB8506869D0 (en) * 1985-03-16 1985-04-17 Wellcome Found Antiviral compound
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
DE3608606A1 (de) * 1985-03-16 1986-09-18 The Wellcome Foundation Ltd., London 3'-azido-3'-deoxythymidin oder eine, ein pharmazeutisch vertraegliches derivat davon enthaltende pharmazeutische formulierung, verfahren zu ihrer herstellung und ihre verwendung
DE3650492T2 (de) * 1985-03-16 1996-10-31 The Wellcome Foundation Ltd., London Therapeutische Nukleoside
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
GB2209669B (en) * 1987-09-11 1992-02-12 Squibb & Sons Inc Pharmaceutical composition containing high drug load and method for preparing same

Also Published As

Publication number Publication date
KR880010759A (ko) 1988-10-24
KR960013434B1 (ko) 1996-10-05
EP0284407B1 (en) 1991-05-29
GB8707421D0 (en) 1987-04-29
IE880899L (en) 1988-09-27
NZ224026A (en) 1991-03-26
ES2033426T3 (es) 1993-03-16
ATE63818T1 (de) 1991-06-15
DK175348B1 (da) 2004-09-06
EP0284407A3 (en) 1988-12-14
DE3862974D1 (de) 1991-07-04
GR3002030T3 (en) 1992-12-30
JP2719344B2 (ja) 1998-02-25
JPS63255230A (ja) 1988-10-21
PT87081B (pt) 1992-07-31
US4917900A (en) 1990-04-17
CA1308026C (en) 1992-09-29
AU1375688A (en) 1988-09-29
ZA882168B (en) 1989-11-29
IE60605B1 (en) 1994-07-27
PT87081A (pt) 1988-04-01
DK164388D0 (da) 1988-03-25
DK164388A (da) 1988-09-28
AU607474B2 (en) 1991-03-07
EP0284407A2 (en) 1988-09-28

Similar Documents

Publication Publication Date Title
IL85870A (en) Controlled release pharmaceutical compositions for oral administration containing 3'-azido-3'-deoxythymidine
IL78158A (en) Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine
IL88363A0 (en) Fluorocytidine derivatives,their production and pharmaceutical compositions containing them
IL88670A0 (en) 2,5-diaryl-tetrahydrofurans and analogs thereof and pharmaceutical compositions containing them
IL87972A (en) Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives, their preparation and pharmaceutical compositions containing them
NZ224024A (en) Acrivastine sustained release compositions
DE3785570D1 (de) Zusammensetzungen enthaltend lhrh-analoga.
IL86798A0 (en) 2,2-dimethylchroman-3-ol derivatives,their preparation and pharmaceutical compositions containing them
IL88330A0 (en) 2',3'-dideoxy-2'-fluoro-nucleosides,their preparation and pharmaceutical compositions containing them
IL95158A0 (en) Pharmaceutical composition for oral administration containing n-acetyl-cysteine
ES8207184A1 (es) Procedimiento para la preparacion de composiciones fosfoli- pidicas de colina
IL74376A (en) 2,5-diaryl tetrahydrothiophenes and analogs thereof,their preparation and pharmaceutical compositions containing them
IL88002A0 (en) 2,2-dimethylchromene derivatives,their preparation and pharmaceutical compositions containing them
IL79134A (en) Continuous release peptide implants for parenteral administration
AU6062286A (en) Continuous release phenylethanolamine derivative compositions
DE69116423D1 (de) 3'-Deamino-4'-deoxy-4'-amino-8-fluoranthracycline und Verfahren zu ihrer Herstellung
IL100593A0 (en) Human bfgf derivatives and their analogs,their production and pharmaceutical compositions containing them
AU8243391A (en) 5'-vinylhalo-aristeromycin/adenosine analogs as immunosuppressants
IL87865A0 (en) Pharmaceutical compositions containing 1(2h)-phthalazinones and their preparation
IL86150A (en) 3,4-dideoxy-d- hexopyranoside- nitrosourea derivatives, their preparation and pharmaceutical compositions containing them
IL87792A0 (en) 1,3-diazocycloalkene derivatives,their preparation and pharmaceutical compositions containing them
IE871940L (en) Controlled release pharmaceutical compositions.

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired