GB2209669B - Pharmaceutical composition containing high drug load and method for preparing same - Google Patents

Pharmaceutical composition containing high drug load and method for preparing same

Info

Publication number
GB2209669B
GB2209669B GB8821209A GB8821209A GB2209669B GB 2209669 B GB2209669 B GB 2209669B GB 8821209 A GB8821209 A GB 8821209A GB 8821209 A GB8821209 A GB 8821209A GB 2209669 B GB2209669 B GB 2209669B
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical composition
composition containing
containing high
drug load
high drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8821209A
Other versions
GB2209669A (en
GB8821209D0 (en
Inventor
John Russell Howard
Anne Marie Delargy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB8821209D0 publication Critical patent/GB8821209D0/en
Publication of GB2209669A publication Critical patent/GB2209669A/en
Application granted granted Critical
Publication of GB2209669B publication Critical patent/GB2209669B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8821209A 1987-09-11 1988-09-09 Pharmaceutical composition containing high drug load and method for preparing same Expired - Lifetime GB2209669B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9549887A 1987-09-11 1987-09-11

Publications (3)

Publication Number Publication Date
GB8821209D0 GB8821209D0 (en) 1988-10-12
GB2209669A GB2209669A (en) 1989-05-24
GB2209669B true GB2209669B (en) 1992-02-12

Family

ID=22252273

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8821209A Expired - Lifetime GB2209669B (en) 1987-09-11 1988-09-09 Pharmaceutical composition containing high drug load and method for preparing same

Country Status (6)

Country Link
JP (1) JP2804048B2 (en)
CA (1) CA1334074C (en)
DE (1) DE3830749A1 (en)
FR (1) FR2620332A1 (en)
GB (1) GB2209669B (en)
IT (1) IT1227336B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
DE3932378A1 (en) * 1989-09-28 1991-04-11 Knoll Ag SOLID MEDICAL FORM WITH A HIGH VERAPAMIL CONTENT
GB2264639B (en) * 1992-02-20 1996-05-22 Euro Celtique Sa Modified Release Formulation
FR2705677B1 (en) * 1993-05-28 1995-08-11 Roquette Freres Micro-granules obtained by extrusion-spheronization containing a cyclodextrin.
WO1999034780A1 (en) * 1998-01-12 1999-07-15 Bühler AG Method and device for capsulating active ingredients
EP2144599B1 (en) 2007-03-02 2010-08-04 Farnam Companies, Inc. Sustained release pellets comprising wax-like material
US20100278880A1 (en) * 2008-01-02 2010-11-04 Biotech Tools S.A. Pharmaceutical formulation for allergen preparation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090739A (en) * 1980-12-22 1982-07-21 Monsanto Co Directly compressible acetaminophen granulation
GB2098867A (en) * 1981-05-21 1982-12-01 Wyeth John & Brother Ltd Sustained release pharmaceutical composition
EP0172014A2 (en) * 1984-08-17 1986-02-19 The Upjohn Company Formulations of ibuprofen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA935093A (en) * 1969-07-28 1973-10-09 Eurand S.R.L. Method of preparing granules with controlled release of the active substance contained therein
BE795766A (en) * 1972-02-22 1973-08-22 Lilly Co Eli PROPOXYPHENE DELAY NAPSYLATE PARTICLES AND PROCESS FOR MANUFACTURING SUCH PARTICLES
DE2416903A1 (en) * 1974-04-06 1975-10-09 Bayer Ag USE OF MELT-SPRAYED BALL-SHAPED PHENACETIN GRANULES FOR THE MANUFACTURING OF TABLETS IN THE DIRECT TABLET PROCESS
DE2446058A1 (en) * 1974-09-26 1976-04-08 Henning Berlin Gmbh GALENIC PREPARATION FOR ALLOPURINOL CONTINUOUS THERAPY
US4115563A (en) * 1977-03-14 1978-09-19 Sterling Drug Inc. Pharmaceutical steroid formulation
JPS5411226A (en) * 1977-06-24 1979-01-27 Shin Etsu Chem Co Ltd Disintegratable granule
US4439453A (en) * 1980-12-22 1984-03-27 Monsanto Company Directly compressible acetaminophen granulation
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
DE3410732A1 (en) * 1984-03-23 1985-09-26 Hoechst Ag, 6230 Frankfurt METHOD FOR TREATING GLAUCOMA
US4639458A (en) * 1985-01-22 1987-01-27 Merck & Co., Inc. Tablet and formulation
IL81419A0 (en) * 1986-01-30 1987-08-31 Syntex Inc Long acting sustained release pharmaceutical compositions containing dihydropyridines and their preparation
US4670422A (en) * 1986-03-27 1987-06-02 E. R. Squibb & Sons, Inc. α-acyloxy phosphonate angiotensin converting enzyme inhibitors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090739A (en) * 1980-12-22 1982-07-21 Monsanto Co Directly compressible acetaminophen granulation
GB2098867A (en) * 1981-05-21 1982-12-01 Wyeth John & Brother Ltd Sustained release pharmaceutical composition
EP0172014A2 (en) * 1984-08-17 1986-02-19 The Upjohn Company Formulations of ibuprofen

Also Published As

Publication number Publication date
IT8821892A0 (en) 1988-09-09
IT1227336B (en) 1991-04-08
FR2620332A1 (en) 1989-03-17
JPH01156913A (en) 1989-06-20
GB2209669A (en) 1989-05-24
GB8821209D0 (en) 1988-10-12
JP2804048B2 (en) 1998-09-24
CA1334074C (en) 1995-01-24
DE3830749A1 (en) 1989-03-30

Similar Documents

Publication Publication Date Title
NZ223630A (en) Insulin derivative and pharmaceutical compositions
HUT48267A (en) Process for producing fluoro-citidin derivatives and pharmaceutical compositions containing them
GB2221157B (en) Intravenous pharmaceutical composition comprising cyclosporin and process for preparing the same
HUT48900A (en) Process for producing phosphoruus-containing squalene-synthetase inhibitores and pharmaceutical compositions containing them
HUT53644A (en) Process for producing pharmaceutical nukleozides and pharmaceutical compositions containing them
EP0326618A4 (en) Medicinal composition containing albumin as carrier and process for its preparation.
HUT51222A (en) Process for producing 9-halogen-/z/-prostaglandin derivatives and pharmaceutical compositions comprising such active ingredient
IL87079A0 (en) Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them
HUT48247A (en) Process for producing aza-bicyclo-octyl-ether derivatives and pharmaceutical compositions containing them as active components
HUT48269A (en) Process for producing pharmaceutically active nukleozide and pharmaceutical compositions containing them
NZ226445A (en) Aminopyridine derivatives and pharmaceutical compositions containing such
PT86516A (en) Process for the preparation of heteroaryl-3-oxo-propani-nitrile derivatives and of pharmaceutical compositions containing the same
IL85969A0 (en) Ribofuranuronic acid derivatives and pharmaceutical compositions containing them
GB8924286D0 (en) Pharmaceutical composition and process for preparing the same
HUT50121A (en) Process for producing piperidinyl-derivatives and pharmaceutical compositions containing them
HUT47079A (en) Process for producing n-amino-butyl-n-phenyl-aryl-amide derivatives and pharmaceutical compositions containing them
HUT48870A (en) Process for producing aminoalkoxyphenyl derivatives and pharmaceutical compositions comprising same
HUT42774A (en) Process for preparing spirodioxolane-, spirodithiolane and spirooxa-thiolane-derivatives and pharmaceutical compositions comprising such compounds
IL85290A0 (en) Substituted 3,4-dihydro-2h-benzopyrans,processes for their preparation and pharmaceutical compositions containing same
HUT48244A (en) Process for producing isoxazol-3-carbolin derivatives and pharmaceutical compositions containing them
PH24992A (en) Alkadiene derivatives and pharmaceutical composition containing them
HUT46692A (en) Process for producing imidazo-pyridine derivatives and pharmaceutical compositions containing them
GB2209669B (en) Pharmaceutical composition containing high drug load and method for preparing same
PT82960A (en) Process for preparing 5-substituted-6-amino-pyrimidine derivatives and pharmaceutical compositions containing them
HUT46689A (en) Process for producing benzimidazole derovatives and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20080908