IL85342A - 3-aminomethyl- dihydrobenzofuran - dihydrobenzothiophene and -indoline derivatives and 1-aminomethyl-indane derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

3-aminomethyl- dihydrobenzofuran - dihydrobenzothiophene and -indoline derivatives and 1-aminomethyl-indane derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL85342A
IL85342A IL85342A IL8534288A IL85342A IL 85342 A IL85342 A IL 85342A IL 85342 A IL85342 A IL 85342A IL 8534288 A IL8534288 A IL 8534288A IL 85342 A IL85342 A IL 85342A
Authority
IL
Israel
Prior art keywords
aminomethyl
derivatives
dihydrobenzothiophene
preparation
dihydrobenzofuran
Prior art date
Application number
IL85342A
Other languages
English (en)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of IL85342A publication Critical patent/IL85342A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL85342A 1987-02-26 1988-02-07 3-aminomethyl- dihydrobenzofuran - dihydrobenzothiophene and -indoline derivatives and 1-aminomethyl-indane derivatives, process for their preparation and pharmaceutical compositions containing them IL85342A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878704572A GB8704572D0 (en) 1987-02-26 1987-02-26 Organic compounds

Publications (1)

Publication Number Publication Date
IL85342A true IL85342A (en) 1993-01-14

Family

ID=10613009

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85342A IL85342A (en) 1987-02-26 1988-02-07 3-aminomethyl- dihydrobenzofuran - dihydrobenzothiophene and -indoline derivatives and 1-aminomethyl-indane derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (2) US4847254A (pt)
EP (1) EP0281261B1 (pt)
JP (1) JP2677588B2 (pt)
AT (1) ATE75723T1 (pt)
AU (1) AU608293B2 (pt)
CA (1) CA1338934C (pt)
DE (1) DE3870666D1 (pt)
DK (1) DK170636B1 (pt)
ES (1) ES2037208T3 (pt)
FI (1) FI97380C (pt)
GB (1) GB8704572D0 (pt)
GR (1) GR3004984T3 (pt)
IE (1) IE61257B1 (pt)
IL (1) IL85342A (pt)
NO (1) NO169119C (pt)
NZ (1) NZ223440A (pt)
PT (1) PT86836B (pt)
ZA (1) ZA881217B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2693843B2 (ja) * 1988-01-15 1997-12-24 アボツト・ラボラトリーズ １―アミノメチル―１，２，３，４―テトラヒドロナフタレン
JP2931986B2 (ja) * 1989-02-17 1999-08-09 武田薬品工業株式会社 アラルキルアミン誘導体
ATE121740T1 (de) * 1989-03-22 1995-05-15 Ciba Geigy Ag Neue benzothiopyranylamine.
JPH0318935A (ja) * 1989-06-15 1991-01-28 Hitachi Ltd データリストに対するアクセスの直列化方式
US5500444A (en) * 1989-11-14 1996-03-19 Hoechst Marion Roussel, Inc. Cardioprotective tocopherol analogs
TW199152B (pt) * 1990-11-01 1993-02-01 Takeda Pharm Industry Co Ltd
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
DK36291D0 (da) * 1991-03-01 1991-03-01 Lundbeck & Co As H Anvendelse af piperidylsubstituerede indolderivater til behandling af kognitive lidelser
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
EP0550292A1 (en) * 1992-01-02 1993-07-07 Merrell Dow Pharmaceuticals Inc. Tissue protective tocopherol analogs
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
ATE158287T1 (de) * 1992-04-06 1997-10-15 Merrell Pharma Inc Derivate von 2,3-dihydro-2,2,4,6,7-pentaalkyl-5- benzofuranen
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
DK55192D0 (da) * 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
DK148292D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Forbindelser
EP0679649B1 (en) * 1993-01-12 2000-04-26 Asahi Kasei Kogyo Kabushiki Kaisha 2,3-Dihydrobenzofuran Derivatives
US5792791A (en) * 1993-01-12 1998-08-11 Asahi Kasei Kogyo Kabushiki Kaisha 2,3-dihydrobenzofuran derivatives
AU1440395A (en) * 1993-12-21 1995-07-10 Eli Lilly And Company Methods for the treatment or prevention of conditions associated with amyloidogenic reptides
WO1995029911A1 (en) * 1994-04-28 1995-11-09 Merck Sharp & Dohme Limited Benzofuran derivatives as d4 receptor antagonists
WO1996001816A1 (fr) * 1994-07-07 1996-01-25 Asahi Kasei Kogyo Kabushiki Kaisha Nouveau derive de 2,3-dihydrobenzofuranne, son procede de production et son utilisation
JPH09124643A (ja) * 1995-08-14 1997-05-13 Bristol Myers Squibb Co 抗うつ作用を有する１−アリールアルキル−４−（アルコキシピリジニル）−又は４−（アルコキシピリミジニル）ピペラジン誘導体
GB9521347D0 (en) * 1995-10-18 1995-12-20 Merck Sharp & Dohme Therapeutic agents
JP2001501946A (ja) * 1996-10-08 2001-02-13 イーライ・リリー・アンド・カンパニー 新規セロトニン５―ｈｔ▲下１ｆ▼アゴニスト
WO1998055454A2 (en) * 1997-06-05 1998-12-10 Takeda Chemical Industries, Ltd. Benzofurans and benzothophenes as suppressors of neurodegeneration
AU2001278875B2 (en) * 2000-07-06 2007-06-07 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tetrahydrobenzothiazole analogues as neuroprotective agents
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE623403A (pt) * 1962-08-08
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
US3513239A (en) * 1967-03-15 1970-05-19 Smithkline Corp Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith
BE786748A (fr) * 1971-07-26 1973-01-26 Basf Ag 1-aminomethyl-indanes-n-substitues
CH601166A5 (pt) * 1974-02-14 1978-06-30 Ciba Geigy Ag
JPS535146A (en) * 1976-07-02 1978-01-18 Tanabe Seiyaku Co Ltd Indane derivatives and their preparation
US4505932A (en) * 1983-05-13 1985-03-19 Abbott Laboratories Method of producing α2 -adrenergic receptor agonist activity
US4777168A (en) * 1984-10-23 1988-10-11 Rorer Pharmaceutical Corporation Bicyclic benzo-oxy heterocyclic ethers and thioethers, pharmaceutical compositions and use

Also Published As

Publication number Publication date
PT86836B (pt) 1992-05-29
GB8704572D0 (en) 1987-04-01
IE880297L (en) 1988-08-26
NO169119C (no) 1992-05-13
DE3870666D1 (de) 1992-06-11
AU1216788A (en) 1988-09-01
NO880833D0 (no) 1988-02-25
FI880906A (fi) 1988-08-27
NZ223440A (en) 1991-02-26
DK91488D0 (da) 1988-02-23
AU608293B2 (en) 1991-03-28
ZA881217B (en) 1989-01-25
FI97380C (fi) 1996-12-10
US4946863A (en) 1990-08-07
FI97380B (fi) 1996-08-30
EP0281261A3 (en) 1989-11-23
GR3004984T3 (pt) 1993-04-28
NO880833L (no) 1988-08-29
ES2037208T3 (es) 1993-06-16
ATE75723T1 (de) 1992-05-15
JP2677588B2 (ja) 1997-11-17
US4847254A (en) 1989-07-11
DK91488A (da) 1988-08-27
IE61257B1 (en) 1994-10-19
NO169119B (no) 1992-02-03
EP0281261A2 (en) 1988-09-07
FI880906A0 (fi) 1988-02-26
EP0281261B1 (en) 1992-05-06
PT86836A (pt) 1988-03-01
CA1338934C (en) 1997-02-25
DK170636B1 (da) 1995-11-20
JPS63264557A (ja) 1988-11-01

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