IL84301A - Preparation of 2-(1-substituted-3-guanidino)-4-(2-alkyl-4-imidazolyl)thiazole and the crystalline trihydrate thereof - Google Patents

Preparation of 2-(1-substituted-3-guanidino)-4-(2-alkyl-4-imidazolyl)thiazole and the crystalline trihydrate thereof

Info

Publication number
IL84301A
IL84301A IL84301A IL8430187A IL84301A IL 84301 A IL84301 A IL 84301A IL 84301 A IL84301 A IL 84301A IL 8430187 A IL8430187 A IL 8430187A IL 84301 A IL84301 A IL 84301A
Authority
IL
Israel
Prior art keywords
alkyl
imidazolyl
preparation
thiazole
guanidino
Prior art date
Application number
IL84301A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1986/002308 external-priority patent/WO1988003141A1/fr
Priority claimed from PCT/US1986/002307 external-priority patent/WO1988003140A1/fr
Application filed by Pfizer filed Critical Pfizer
Publication of IL84301A publication Critical patent/IL84301A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28—Y being a hetero atom, e.g. thiobiuret

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
IL84301A 1986-10-29 1987-10-28 Preparation of 2-(1-substituted-3-guanidino)-4-(2-alkyl-4-imidazolyl)thiazole and the crystalline trihydrate thereof IL84301A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1986/002308 WO1988003141A1 (fr) 1986-10-29 1986-10-29 Procedes pour 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyle)-thiazole et analogues
PCT/US1986/002307 WO1988003140A1 (fr) 1986-10-29 1986-10-29 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol dihydrochlorure trihydrate cristallin

Publications (1)

Publication Number Publication Date
IL84301A true IL84301A (en) 1992-08-18

Family

ID=26774088

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84301A IL84301A (en) 1986-10-29 1987-10-28 Preparation of 2-(1-substituted-3-guanidino)-4-(2-alkyl-4-imidazolyl)thiazole and the crystalline trihydrate thereof

Country Status (14)

Country Link
EP (1) EP0269239B1 (fr)
KR (1) KR900002343B1 (fr)
CN (1) CN1022567C (fr)
AT (1) ATE106884T1 (fr)
DE (1) DE3750023T2 (fr)
DK (1) DK565187A (fr)
EG (1) EG18271A (fr)
ES (1) ES2054684T3 (fr)
IE (1) IE872897L (fr)
IL (1) IL84301A (fr)
NZ (1) NZ222306A (fr)
PL (1) PL149549B1 (fr)
PT (1) PT86011B (fr)
YU (1) YU46081B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002127A1 (fr) * 1988-08-30 1990-03-08 Pfizer Inc. Hemihydrate hemiphosphate de 2-(1-pentyl-3-guanidino-4-imidazolyl)thyazole
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
CN100384237C (zh) * 2004-02-28 2008-04-23 鸿富锦精密工业（深圳）有限公司 音量调整装置及方法
CN100517961C (zh) * 2004-04-03 2009-07-22 鸿富锦精密工业（深圳）有限公司 音量调整装置及方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US391473A (en) * 1888-10-23 Feedeeick j
US3798269A (en) * 1968-08-05 1974-03-19 R Cutler Amidinoureas and amidinothioureas
US4374843A (en) * 1980-10-14 1983-02-22 Pfizer Inc. 2-Guanidino-4-heteroarylthiazoles
US4435396A (en) * 1982-05-10 1984-03-06 Pfizer Inc. Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents

Also Published As

Publication number Publication date
YU195787A (en) 1988-12-31
NZ222306A (en) 1989-09-27
KR900002343B1 (ko) 1990-04-12
EP0269239A2 (fr) 1988-06-01
IE872897L (en) 1988-04-29
KR880005124A (ko) 1988-06-28
DE3750023T2 (de) 1994-09-29
EP0269239A3 (en) 1990-03-28
DK565187A (da) 1988-04-30
CN1022567C (zh) 1993-10-27
ES2054684T3 (es) 1994-08-16
EG18271A (en) 1992-12-30
PT86011B (pt) 1990-08-31
DE3750023D1 (de) 1994-07-14
ATE106884T1 (de) 1994-06-15
YU46081B (sh) 1992-12-21
PT86011A (en) 1987-11-01
PL268454A1 (en) 1988-09-01
CN87107492A (zh) 1988-05-11
PL149549B1 (en) 1990-02-28
DK565187D0 (da) 1987-10-28
EP0269239B1 (fr) 1994-06-08

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Legal Events

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