IL84167A - Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation - Google Patents

Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation

Info

Publication number
IL84167A
IL84167A IL84167A IL8416787A IL84167A IL 84167 A IL84167 A IL 84167A IL 84167 A IL84167 A IL 84167A IL 8416787 A IL8416787 A IL 8416787A IL 84167 A IL84167 A IL 84167A
Authority
IL
Israel
Prior art keywords
peyer
patch
microencapsulation
bioactive agents
oral delivery
Prior art date
Application number
IL84167A
Other languages
English (en)
Other versions
IL84167A0 (en
Original Assignee
Southern Res Inst
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36954601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL84167(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Southern Res Inst, Uab Research Foundation filed Critical Southern Res Inst
Publication of IL84167A0 publication Critical patent/IL84167A0/xx
Publication of IL84167A publication Critical patent/IL84167A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL84167A 1986-10-24 1987-10-13 Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation IL84167A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92315986A 1986-10-24 1986-10-24
CN95100893A CN1111157A (zh) 1986-10-24 1995-03-08 用于到达派亚氏淋巴结的口服生物活性剂的制法和配方

Publications (2)

Publication Number Publication Date
IL84167A0 IL84167A0 (en) 1988-03-31
IL84167A true IL84167A (en) 1991-04-15

Family

ID=36954601

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84167A IL84167A (en) 1986-10-24 1987-10-13 Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation

Country Status (15)

Country Link
EP (1) EP0266119B2 (xx)
JP (1) JP2741728B2 (xx)
KR (1) KR900003559B1 (xx)
CN (1) CN1111157A (xx)
AT (1) ATE108650T1 (xx)
AU (1) AU607439B2 (xx)
CA (1) CA1331738C (xx)
DE (1) DE3750247T2 (xx)
DK (1) DK175859B1 (xx)
ES (1) ES2056068T3 (xx)
HK (1) HK122495A (xx)
IE (1) IE64786B1 (xx)
IL (1) IL84167A (xx)
NZ (1) NZ222278A (xx)
ZA (1) ZA877946B (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
JP2664906B2 (ja) * 1987-08-13 1997-10-22 ストール・リサーチ・アンド・デイベロップメント・コーポレーション 改良された哺乳類の免疫法
US5444113A (en) * 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
AU642932B2 (en) * 1989-11-06 1993-11-04 Alkermes Controlled Therapeutics, Inc. Protein microspheres and methods of using them
JP3249147B2 (ja) * 1990-06-01 2002-01-21 キリン−アムジエン・インコーポレーテツド 生理活性蛋白含有経口製剤
ES2108111T3 (es) * 1991-04-02 1997-12-16 Biotech Australia Pty Ltd Sistemas de suministro oral de microparticulas.
US5912015A (en) 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US6514533B1 (en) 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
AU4932493A (en) * 1992-09-25 1994-04-26 Dynagen, Inc. An immunobooster for delayed release of immunogen
DK0724433T3 (da) * 1993-10-22 1999-08-30 Genentech Inc Fremgangsmåde til fremstilling af mikrosfærer med et tørringstrin i fluidiseret leje
US6913767B1 (en) 1993-10-25 2005-07-05 Genentech, Inc. Compositions for microencapsulation of antigens for use as vaccines
US6080429A (en) * 1993-10-25 2000-06-27 Genentech, Inc. Method for drying microspheres
ES2236700T3 (es) * 1993-11-19 2005-07-16 Janssen Pharmaceutica N.V. 1,2-benzazoles microencapsulados.
US5902565A (en) * 1993-12-24 1999-05-11 Csl Limited Spray dried vaccine preparation comprising aluminium adsorbed immunogens
US6531156B1 (en) 1994-04-15 2003-03-11 Temple University Aqueous solven encapsulation method, apparatus and microcapsules
KR100201352B1 (ko) * 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
US6265389B1 (en) 1995-08-31 2001-07-24 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of oligonucleotides
AU710347B2 (en) * 1995-08-31 1999-09-16 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
WO1997017063A1 (en) * 1995-11-09 1997-05-15 Microbiological Research Authority Microencapsulated dna for vaccination and gene therapy
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
DE19545257A1 (de) * 1995-11-24 1997-06-19 Schering Ag Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
US5980948A (en) * 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
US5783567A (en) * 1997-01-22 1998-07-21 Pangaea Pharmaceuticals, Inc. Microparticles for delivery of nucleic acid
US6197229B1 (en) * 1997-12-12 2001-03-06 Massachusetts Institute Of Technology Method for high supercoiled DNA content microspheres
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
WO1999065531A1 (en) 1998-06-18 1999-12-23 Johns Hopkins University School Of Medicine Polymers for delivery of nucleic acids
JP4601823B2 (ja) 1998-09-01 2010-12-22 メリオン リサーチ スリー リミテッド 経口ワクチン組成物
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
WO2000045847A1 (en) 1999-02-05 2000-08-10 Alk-Abelló A/S Novel mucosal delivery system
US20020051794A1 (en) 2000-08-09 2002-05-02 Alk-Abello A/S Novel parenteral vaccine formulations and uses thereof
CA2451741C (en) * 2001-07-02 2014-02-18 Elan Corporation, Plc Peyers's patch and/or m-celle targeting ligands
GB0300881D0 (en) * 2003-01-15 2003-02-12 Secr Defence Therapeutic treatment
JP6334214B2 (ja) * 2013-03-08 2018-05-30 学校法人慶應義塾 レーザーを用いた薬剤放出方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3823228A (en) * 1971-09-29 1974-07-09 Univ Illinois Tge virus vaccine
IL54167A (en) * 1977-03-14 1980-05-30 Baxter Travenol Lab Frangible protective sealing arrangement
AU526320B2 (en) * 1979-04-27 1983-01-06 Acme Fluid Foundry Pty. Ltd. Manway cover fastening assembly
AU567155B2 (en) * 1983-04-15 1987-11-12 Damon Biotech Inc. Capsules for releasing core material at constant rate
IL72106A (en) * 1983-06-22 1988-02-29 Univ Ohio State Res Found Process for microencapsulating a weakly acidic or basic organic compound
GB2144950A (en) * 1983-08-10 1985-03-13 Philips Electronic Associated Data transmission system

Also Published As

Publication number Publication date
AU607439B2 (en) 1991-03-07
CN1111157A (zh) 1995-11-08
DE3750247T2 (de) 1994-10-27
HK122495A (en) 1995-08-04
ZA877946B (en) 1988-04-26
DE3750247D1 (de) 1994-08-25
IE872851L (en) 1988-04-24
KR880004800A (ko) 1988-06-27
ES2056068T3 (es) 1994-10-01
IL84167A0 (en) 1988-03-31
CA1331738C (en) 1994-08-30
EP0266119B2 (en) 2005-05-04
EP0266119A3 (en) 1989-07-26
EP0266119A2 (en) 1988-05-04
JP2741728B2 (ja) 1998-04-22
DK557787D0 (da) 1987-10-23
IE64786B1 (en) 1995-09-06
NZ222278A (en) 1989-09-27
JPS63190833A (ja) 1988-08-08
KR900003559B1 (ko) 1990-05-21
EP0266119B1 (en) 1994-07-20
DK175859B1 (da) 2005-04-11
DK557787A (da) 1988-04-25
AU7992987A (en) 1988-04-28
ATE108650T1 (de) 1994-08-15

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