IL80547A0 - Method for the preparation of immunoglobulins suitable for intravenous administration - Google Patents
Method for the preparation of immunoglobulins suitable for intravenous administrationInfo
- Publication number
- IL80547A0 IL80547A0 IL80547A IL8054786A IL80547A0 IL 80547 A0 IL80547 A0 IL 80547A0 IL 80547 A IL80547 A IL 80547A IL 8054786 A IL8054786 A IL 8054786A IL 80547 A0 IL80547 A0 IL 80547A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- intravenous administration
- chem
- pepsin
- immunoglobulins suitable
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 3
- 102000018358 immunoglobulin Human genes 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- 229940072221 immunoglobulins Drugs 0.000 title abstract 2
- 238000001990 intravenous administration Methods 0.000 title abstract 2
- 102000057297 Pepsin A Human genes 0.000 abstract 2
- 108090000284 Pepsin A Proteins 0.000 abstract 2
- 229940111202 pepsin Drugs 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000007822 coupling agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 230000003100 immobilizing effect Effects 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/091—Phenol resins; Amino resins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/098—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer formed in the presence of the enzymes or microbial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22766/85A IT1186766B (it) | 1985-11-08 | 1985-11-08 | Metodo per la preparazione di immunoglobuline per uso endovenoso |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL80547A0 true IL80547A0 (en) | 1987-02-27 |
Family
ID=11200219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80547A IL80547A0 (en) | 1985-11-08 | 1986-11-07 | Method for the preparation of immunoglobulins suitable for intravenous administration |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0221505B1 (de) |
| JP (1) | JPH07121876B2 (de) |
| AT (1) | ATE66151T1 (de) |
| AU (1) | AU6427886A (de) |
| CA (1) | CA1306964C (de) |
| DE (1) | DE3680860D1 (de) |
| ES (1) | ES2033231T3 (de) |
| GR (1) | GR3002931T3 (de) |
| IL (1) | IL80547A0 (de) |
| IT (1) | IT1186766B (de) |
| ZA (1) | ZA868271B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE465950B (sv) * | 1989-10-23 | 1991-11-25 | Medinvent Sa | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
| US5354461A (en) * | 1991-02-20 | 1994-10-11 | Eisai Co., Ltd. | Packings combining protein to a support via a spacer |
| CA2061519C (en) * | 1991-02-20 | 2004-05-18 | Naoki Asakawa | Packings combining protein to a support via a spacer |
| EP0835880A1 (de) * | 1996-10-14 | 1998-04-15 | Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk | Verfahren zur Herstellung eines IgM Präparates für die intravenöse Applikation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH664496A5 (de) * | 1982-05-31 | 1988-03-15 | Mochida Pharm Co Ltd | Material zur entfernung von immunkomplexen aus dem blut oder aus plasma. |
-
1985
- 1985-11-08 IT IT22766/85A patent/IT1186766B/it active
-
1986
- 1986-10-22 AU AU64278/86A patent/AU6427886A/en not_active Withdrawn
- 1986-10-23 CA CA000521255A patent/CA1306964C/en not_active Expired - Fee Related
- 1986-10-29 EP EP86115016A patent/EP0221505B1/de not_active Expired - Lifetime
- 1986-10-29 DE DE8686115016T patent/DE3680860D1/de not_active Expired - Fee Related
- 1986-10-29 AT AT86115016T patent/ATE66151T1/de not_active IP Right Cessation
- 1986-10-29 ES ES198686115016T patent/ES2033231T3/es not_active Expired - Lifetime
- 1986-10-30 ZA ZA868271A patent/ZA868271B/xx unknown
- 1986-11-07 IL IL80547A patent/IL80547A0/xx unknown
- 1986-11-07 JP JP61264125A patent/JPH07121876B2/ja not_active Expired - Lifetime
-
1991
- 1991-10-17 GR GR91401562T patent/GR3002931T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0221505A2 (de) | 1987-05-13 |
| IT1186766B (it) | 1987-12-16 |
| GR3002931T3 (en) | 1993-01-25 |
| ATE66151T1 (de) | 1991-08-15 |
| DE3680860D1 (de) | 1991-09-19 |
| JPH07121876B2 (ja) | 1995-12-25 |
| IT8522766A0 (it) | 1985-11-08 |
| EP0221505B1 (de) | 1991-08-14 |
| ZA868271B (en) | 1987-06-24 |
| CA1306964C (en) | 1992-09-01 |
| EP0221505A3 (en) | 1988-05-04 |
| JPS62114919A (ja) | 1987-05-26 |
| AU6427886A (en) | 1987-05-14 |
| ES2033231T3 (es) | 1993-03-16 |
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