ES2075028T3 - Procedimiento para la preparacion de tripeptidos. - Google Patents

Procedimiento para la preparacion de tripeptidos.

Info

Publication number
ES2075028T3
ES2075028T3 ES89121277T ES89121277T ES2075028T3 ES 2075028 T3 ES2075028 T3 ES 2075028T3 ES 89121277 T ES89121277 T ES 89121277T ES 89121277 T ES89121277 T ES 89121277T ES 2075028 T3 ES2075028 T3 ES 2075028T3
Authority
ES
Spain
Prior art keywords
general formula
compound
tripeptides
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89121277T
Other languages
English (en)
Inventor
Hans-Wolfram Dr Flemming
Manfred Dr Rukwied
Manfred Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2075028T3 publication Critical patent/ES2075028T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

EL INVENTO SE REFIERE A UN PROCEDIMIENTO PARA PRODUCIR TRIPEPTIDOS DE FORMULA (I) QUE CONSISTE EN TRATAR UN COMPUESTO DE FORMULA (U''-B-OH) CON UN COMPUESTO DE FORMULA (H-C-OR); ELIMINAR U'' DEL COMPUESTO OBTENIDO EN LA ETAPA ANTERIOR SEGUN EL METODO PPA; TRATAR AL COMPUESTO RESULTANTE CON UN COMPUESTO DE FORMULA (H-B-C-OR) SEGUN EL METODO PPA Y ELIMINAR ENZIMATICAMENTE R DEL COMPUESTO OBTENIDO EN LA ETAPA ANTERIOR. SIENDO A, B Y C AMINOACIDOS; U HIDROGENO O UN GRUPO PROTECTOR DE URETANO; Y U'' UN GRUPO PROTECTOR DE URETANO ELIMINABLE HIDROGENOLITICAMENTE.
ES89121277T 1988-11-22 1989-11-17 Procedimiento para la preparacion de tripeptidos. Expired - Lifetime ES2075028T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839379A DE3839379A1 (de) 1988-11-22 1988-11-22 Verfahren zur herstellung von tripeptiden

Publications (1)

Publication Number Publication Date
ES2075028T3 true ES2075028T3 (es) 1995-10-01

Family

ID=6367619

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89121277T Expired - Lifetime ES2075028T3 (es) 1988-11-22 1989-11-17 Procedimiento para la preparacion de tripeptidos.

Country Status (10)

Country Link
EP (1) EP0370399B1 (es)
JP (1) JP2843618B2 (es)
AT (1) ATE124053T1 (es)
AU (1) AU626608B2 (es)
CA (1) CA1335493C (es)
DE (2) DE3839379A1 (es)
DK (1) DK173690B1 (es)
ES (1) ES2075028T3 (es)
IE (1) IE67293B1 (es)
IL (1) IL92368A0 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004029812A1 (de) 2004-06-19 2006-05-24 Clariant Gmbh Verfahren zur Herstellung von Nitrilen aus Aldehydoximen durch Umsetzung mit Alkylphosphonsäureanhydriden
DE102004029811A1 (de) * 2004-06-19 2006-01-12 Clariant Gmbh Verfahren zur Herstellung von Alkenen durch Eliminierung von Wasser aus Alkoholen mit Alkylphosphonsäureanhydriden

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7801373L (sv) * 1978-02-07 1979-08-08 Kabi Ab Lett spjelkbara substrat for kvantifiering av proteaser
US4293648A (en) * 1979-12-12 1981-10-06 G. D. Searle & Co. Process for esterification of α-L-aspartyl-L-phenylalanine
DE3411224A1 (de) * 1984-03-27 1985-10-10 Hoechst Ag, 6230 Frankfurt Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
DE3438189A1 (de) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung aromatisch substituierter l-aminosaeuren
US4888385A (en) * 1987-04-30 1989-12-19 Millipore Corporation BOP reagent for solid phase peptide synthesis
US4946942A (en) * 1988-03-11 1990-08-07 Bioresearch, Inc. Urethane-protected amino acid-N-carboxyanhydrides

Also Published As

Publication number Publication date
EP0370399A2 (de) 1990-05-30
DE58909308D1 (de) 1995-07-27
ATE124053T1 (de) 1995-07-15
IE67293B1 (en) 1996-03-20
EP0370399A3 (de) 1991-09-18
JP2843618B2 (ja) 1999-01-06
IE893717L (en) 1990-05-22
JPH02219587A (ja) 1990-09-03
CA1335493C (en) 1995-05-09
DE3839379A1 (de) 1990-05-23
DK173690B1 (da) 2001-06-25
DK584489D0 (da) 1989-11-21
AU4532889A (en) 1990-05-31
EP0370399B1 (de) 1995-06-21
AU626608B2 (en) 1992-08-06
IL92368A0 (en) 1990-07-26
DK584489A (da) 1990-05-23

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