IL92368A0 - Process for the preparation of tripeptides - Google Patents

Process for the preparation of tripeptides

Info

Publication number
IL92368A0
IL92368A0 IL92368A IL9236889A IL92368A0 IL 92368 A0 IL92368 A0 IL 92368A0 IL 92368 A IL92368 A IL 92368A IL 9236889 A IL9236889 A IL 9236889A IL 92368 A0 IL92368 A0 IL 92368A0
Authority
IL
Israel
Prior art keywords
general formula
compound
tripeptides
reacting
preparation
Prior art date
Application number
IL92368A
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL92368A0 publication Critical patent/IL92368A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Process for preparing tripeptides of the general formula I U-A-B-C-OH I in which U is hydrogen or a urethane protective group and A, B and C are amino acids, by reacting a compound of the general formula II U'-B-OH II in which U' is a urethane protective group which can be eliminated by hydrogenolysis, with a compound of the general formula III H-C-OR III in which R is alkyl, by the PPA method, eliminating U', reacting the compound obtained in this way with a compound of the general formula IV H-B-C-OR IV by the PPA method and subsequently eliminating R enzymatically.
IL92368A 1988-11-22 1989-11-20 Process for the preparation of tripeptides IL92368A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839379A DE3839379A1 (en) 1988-11-22 1988-11-22 METHOD FOR PRODUCING TRIPEPTIDES

Publications (1)

Publication Number Publication Date
IL92368A0 true IL92368A0 (en) 1990-07-26

Family

ID=6367619

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92368A IL92368A0 (en) 1988-11-22 1989-11-20 Process for the preparation of tripeptides

Country Status (10)

Country Link
EP (1) EP0370399B1 (en)
JP (1) JP2843618B2 (en)
AT (1) ATE124053T1 (en)
AU (1) AU626608B2 (en)
CA (1) CA1335493C (en)
DE (2) DE3839379A1 (en)
DK (1) DK173690B1 (en)
ES (1) ES2075028T3 (en)
IE (1) IE67293B1 (en)
IL (1) IL92368A0 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004029811A1 (en) * 2004-06-19 2006-01-12 Clariant Gmbh Process for the preparation of alkenes by elimination of water from alcohols with alkylphosphonic anhydrides
DE102004029812A1 (en) * 2004-06-19 2006-05-24 Clariant Gmbh Process for the preparation of nitriles from aldehyde oximes by reaction with alkylphosphonic anhydrides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7801373L (en) * 1978-02-07 1979-08-08 Kabi Ab EASY SPLABLE SUBSTRATE FOR QUANTIFIATION OF PROTEASES
US4293648A (en) * 1979-12-12 1981-10-06 G. D. Searle & Co. Process for esterification of α-L-aspartyl-L-phenylalanine
DE3411224A1 (en) * 1984-03-27 1985-10-10 Hoechst Ag, 6230 Frankfurt METHOD FOR THE RACEMATAR PRODUCTION OF INTERMEDIATE PEPTIDE PRODUCTS OF THE GONADORELIN AND GONADORELINANALOGA SYNTHESIS AND NEW INTERMEDIATE PRODUCTS IN THIS METHOD
DE3438189A1 (en) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt METHOD FOR PRODUCING AROMATICALLY SUBSTITUTED L-AMINO ACIDS
US4888385A (en) * 1987-04-30 1989-12-19 Millipore Corporation BOP reagent for solid phase peptide synthesis
US4946942A (en) * 1988-03-11 1990-08-07 Bioresearch, Inc. Urethane-protected amino acid-N-carboxyanhydrides

Also Published As

Publication number Publication date
AU626608B2 (en) 1992-08-06
EP0370399A3 (en) 1991-09-18
ATE124053T1 (en) 1995-07-15
DK173690B1 (en) 2001-06-25
EP0370399B1 (en) 1995-06-21
DE3839379A1 (en) 1990-05-23
IE67293B1 (en) 1996-03-20
DK584489A (en) 1990-05-23
DE58909308D1 (en) 1995-07-27
DK584489D0 (en) 1989-11-21
CA1335493C (en) 1995-05-09
AU4532889A (en) 1990-05-31
EP0370399A2 (en) 1990-05-30
ES2075028T3 (en) 1995-10-01
JP2843618B2 (en) 1999-01-06
IE893717L (en) 1990-05-22
JPH02219587A (en) 1990-09-03

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Legal Events

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