ES8605472A1 - Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona - Google Patents

Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona

Info

Publication number
ES8605472A1
ES8605472A1 ES546859A ES546859A ES8605472A1 ES 8605472 A1 ES8605472 A1 ES 8605472A1 ES 546859 A ES546859 A ES 546859A ES 546859 A ES546859 A ES 546859A ES 8605472 A1 ES8605472 A1 ES 8605472A1
Authority
ES
Spain
Prior art keywords
alpha
amino
methylacetyl
aminophenyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546859A
Other languages
English (en)
Other versions
ES546859A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of ES8605472A1 publication Critical patent/ES8605472A1/es
Publication of ES546859A0 publication Critical patent/ES546859A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 1-N-(A-AMINO-A-METILACETIL)-AMINOFENIL-2-AMINO-PROPANONA. CONSISTE EN AMINAR A UN DERIVADO DIHALOGENADO DE FORMULA (II) CON UNA AMINA DE FORMULA (HNRR), EN UNA RELACION I2/1 DE AMINA/DERIVADO HALOGENADO, EN UNAMEZCLA DE ALCOHOL INFERIOR DE C 1 A 3 Y AMINA DE FORMULA (HNRR), A UNA TEMPERATURA ENTRE 15JC Y LA TEMPERATURA DE REFLUJO DEL MEDIO Y DURANTE 1 HORA, PARA OBTENER LAS 1-N-(A-ALQUILAMINO-A-METILACETIL)-AMINOFENIL-2-AMINO-PROPANOS DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDOS. SIENDO: R, ALQUILO DE C 1 A 4; R, H, O UN GRUPO ALQUILO DE C 1 A 4; Y X, F, CL O BR. SE UTILIZAN COMO AGENTES ANTIDEPRESIVOS PARA EL SISTEMA NERVIOSO CENTRAL.
ES546859A 1984-08-20 1985-08-16 Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona Expired ES8605472A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8412964A FR2569186B1 (fr) 1984-08-20 1984-08-20 Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
ES8605472A1 true ES8605472A1 (es) 1986-03-16
ES546859A0 ES546859A0 (es) 1986-03-16

Family

ID=9307108

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546859A Expired ES8605472A1 (es) 1984-08-20 1985-08-16 Procedimiento para la preparacion de derivados de 1-(n-(a- amino-a-metilacetil)-aminofenil)-2-amino-propanona

Country Status (13)

Country Link
US (1) US4690950A (es)
EP (1) EP0174887B1 (es)
JP (1) JPS6165855A (es)
AT (1) ATE28071T1 (es)
AU (1) AU570820B2 (es)
CA (1) CA1292015C (es)
DE (1) DE3560291D1 (es)
DK (1) DK378885A (es)
ES (1) ES8605472A1 (es)
FR (1) FR2569186B1 (es)
GR (1) GR851996B (es)
PT (1) PT80992B (es)
ZA (1) ZA856150B (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2128255A (en) * 1934-12-22 1938-08-30 Gen Aniline Works Inc Azo dyestuffs
DE1015986B (de) * 1955-07-04 1957-09-19 Thomae Gmbh Dr K Licht- und Sonnenschutzmittel
FR1458118A (fr) * 1964-02-26 1966-03-04 Ciba Geigy Nouveaux amino-phényl-alcanols et procédé pour leur préparation
SE410732B (sv) * 1971-12-13 1979-10-29 Sumitomo Chemical Co Analogiforfarande for framstellning av anilidderivat med terapeutisk verkan
US4024282A (en) * 1975-11-25 1977-05-17 Mitsubishi Chemical Industries Ltd. Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes
GB1520812A (en) * 1975-10-02 1978-08-09 Lafon Labor Benzhydrylsulphinyl derivatives
GB1531781A (en) * 1976-03-23 1978-11-08 Lafon Labor N-propargyl-piperonylamine and its preparation and use
CA1086733A (en) * 1976-12-06 1980-09-30 Ryoji Kikumoto Pharmaceutically active 2-substituted-1-(omega- aminoalkoxy) benzenes
US4650771A (en) * 1983-11-04 1987-03-17 Miles Laboratories, Inc. Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof
ATE62222T1 (de) * 1985-02-15 1991-04-15 Res Corp Technologies Inc Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.

Also Published As

Publication number Publication date
CA1292015C (en) 1991-11-12
EP0174887B1 (fr) 1987-07-01
ZA856150B (en) 1986-04-30
FR2569186A1 (fr) 1986-02-21
DK378885D0 (da) 1985-08-20
PT80992A (fr) 1985-09-01
DK378885A (da) 1986-02-21
AU4646485A (en) 1986-02-27
US4690950A (en) 1987-09-01
EP0174887A1 (fr) 1986-03-19
JPS6165855A (ja) 1986-04-04
AU570820B2 (en) 1988-03-24
FR2569186B1 (fr) 1986-09-05
ES546859A0 (es) 1986-03-16
GR851996B (es) 1985-12-17
PT80992B (pt) 1987-09-30
DE3560291D1 (en) 1987-08-06
ATE28071T1 (de) 1987-07-15

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