IL80264A - Complexes of vitamin b12 or its analogues,their preparation and pharmaceutical compositions containing them - Google Patents

Complexes of vitamin b12 or its analogues,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL80264A
IL80264A IL80264A IL8026486A IL80264A IL 80264 A IL80264 A IL 80264A IL 80264 A IL80264 A IL 80264A IL 8026486 A IL8026486 A IL 8026486A IL 80264 A IL80264 A IL 80264A
Authority
IL
Israel
Prior art keywords
complex
vitamin
analogues
complexes
preparation
Prior art date
Application number
IL80264A
Other languages
English (en)
Other versions
IL80264A0 (en
Original Assignee
Biotech Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3771313&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL80264(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotech Australia Pty Ltd filed Critical Biotech Australia Pty Ltd
Publication of IL80264A0 publication Critical patent/IL80264A0/xx
Publication of IL80264A publication Critical patent/IL80264A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Vending Machines For Individual Products (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
IL80264A 1985-10-10 1986-10-09 Complexes of vitamin b12 or its analogues,their preparation and pharmaceutical compositions containing them IL80264A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPH283885 1985-10-10

Publications (2)

Publication Number Publication Date
IL80264A0 IL80264A0 (en) 1987-01-30
IL80264A true IL80264A (en) 1991-11-21

Family

ID=3771313

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80264A IL80264A (en) 1985-10-10 1986-10-09 Complexes of vitamin b12 or its analogues,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (2) US5428023A (instruction)
EP (1) EP0220030B1 (instruction)
JP (1) JPH08779B2 (instruction)
KR (1) KR940003057B1 (instruction)
CN (1) CN1045391C (instruction)
AT (1) ATE64534T1 (instruction)
CA (1) CA1330791C (instruction)
DK (1) DK167099B1 (instruction)
ES (1) ES2051690T3 (instruction)
GR (1) GR3002160T3 (instruction)
HK (1) HK69094A (instruction)
IL (1) IL80264A (instruction)
IN (1) IN165029B (instruction)
NZ (1) NZ217821A (instruction)
WO (1) WO1987002251A1 (instruction)
ZA (1) ZA867703B (instruction)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643889A (en) * 1984-07-11 1997-07-01 Temple University-Of The Commonwealth System Of Pennsylvania Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof
US5550111A (en) * 1984-07-11 1996-08-27 Temple University-Of The Commonwealth System Of Higher Education Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US4842868A (en) * 1986-09-26 1989-06-27 Helwing Robert F Covalently bonded active agents with carbonium ion base groups
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
US4997815A (en) * 1988-11-01 1991-03-05 Children's Hospital Medical Center Of Northern California Method for augmenting fetal hemoglobin by treatment with activin and/or inhibin
US5108921A (en) * 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
AU5356490A (en) * 1989-04-03 1990-11-05 Purdue Research Foundation Method for enhancing transmembrane transport of exogenous molecules
US5688488A (en) * 1989-04-03 1997-11-18 Purdue Research Foundation Composition and method for tumor imaging
FR2649321A1 (fr) * 1989-07-07 1991-01-11 Inst Nat Sante Rech Med Compositions a base de derives nucleotidiques, leurs procedes de preparation, et leurs utilisations notamment en tant que compositions pharmaceutiques
GR900100249A (el) * 1990-03-28 1992-06-30 Purdue Research Foundation Μεθοδος δια την ηυξημενην δια των μεμβρανων μεταφοραν εξωγενων μοριων.
ES2108111T3 (es) * 1991-04-02 1997-12-16 Biotech Australia Pty Ltd Sistemas de suministro oral de microparticulas.
CA2163225A1 (en) * 1993-05-20 1994-12-08 Gregory John Russell-Jones Lhrh antagonists
US5449720A (en) * 1993-05-24 1995-09-12 Biotech Australia Pty Limited Amplification of the VB12 uptake system using polymers
US5548064A (en) * 1993-05-24 1996-08-20 Biotech Australia Pty Limited Vitamin B12 conjugates with EPO, analogues thereof and pharmaceutical compositions
CA2187346C (en) * 1994-04-08 2010-06-29 A. Charles Morgan, Jr. Receptor modulating agents and methods relating thereto
US5840880A (en) * 1994-04-08 1998-11-24 Receptagen Corporation Receptor modulating agents
US5739287A (en) * 1994-04-08 1998-04-14 University Of Washington Biotinylated cobalamins
US5869465A (en) * 1994-04-08 1999-02-09 Receptagen Corporation Methods of receptor modulation and uses therefor
US5574018A (en) * 1994-07-29 1996-11-12 Amgen Inc. Conjugates of vitamin B12 and proteins
EP0781142A4 (en) * 1994-09-01 2003-04-09 Allied Medical Res Associates Compositions and methods for delivery of polypeptides
NZ323127A (en) * 1995-10-19 2001-03-30 Receptagen Corp Vitamin B12 receptor modulating agents and methods related thereto
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
WO1998008859A1 (en) 1996-08-27 1998-03-05 University Of Utah Research Foundation Bioconjugates and delivery of bioactive agents
US6054133A (en) * 1997-07-10 2000-04-25 The Regents Of The University Of California Anti-microbial targeting for intracellular pathogens
AU4328399A (en) * 1998-06-15 2000-01-05 Alza Corporation Nucleic acid-cobalamin complexes and their use in gene therapy
FR2787029A1 (fr) * 1998-12-09 2000-06-16 Biovector Therapeutics Utilisation dans une composition pharmaceutique pour l'administration par voie nasale de vitamine b12 pour la delivrance d'agents actifs au systeme nerveux central
US20010008627A1 (en) 1999-01-22 2001-07-19 Soll David R. Hiv-encoded chemoattractant
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
DE19930729A1 (de) * 1999-07-05 2001-01-11 Achim Goepferich Blockcopolymere zur Herstellung biomimetischer Oberflächen
EP1239887A1 (en) 1999-10-15 2002-09-18 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
JP2003512338A (ja) * 1999-10-15 2003-04-02 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 造影剤および抗腫瘍薬として有用なコバラミン結合体
US7591995B2 (en) 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
CN1441676B (zh) 2000-03-31 2012-08-22 普渡研究基金会 用配体-免疫原缀合物治疗的方法
AU2002243438A1 (en) * 2000-10-25 2002-07-24 Mayo Foundation For Medical Education And Research Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
EP1754712A3 (en) * 2000-10-25 2009-01-14 Mayo Foundation For Medical Education And Research Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
GB2374010B (en) * 2001-02-26 2004-12-29 Council Scient Ind Res Novel vitamin B12 - biodegradable micro particulate conjugate carrier systems for peroral delivery of drugs, therapeutic peptides/proteins and vaccines
NZ529808A (en) 2001-05-02 2007-02-23 Purdue Research Foundation Treatment and diagnosis of macrophage mediated disease
US6752986B2 (en) 2001-05-24 2004-06-22 The Cleveland Clinic Foundation Composition and methods for affecting metallocorrinoid uptake
WO2003000010A2 (en) * 2001-06-20 2003-01-03 Mayo Foundation For Medical Education And Research Adenosyl-cobalamin fortified compositions
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
EP1434603B1 (en) * 2001-09-28 2009-12-16 Purdue Research Foundation Method of treatment using ligand-immunogen conjugates
US20030144198A1 (en) * 2001-09-28 2003-07-31 Collins Douglas A. Coadministration of transport protein with conjugated cobalamin to deliver agents
US7255874B1 (en) 2001-12-21 2007-08-14 Closure Medical Corporation Biocompatible polymers and adhesives: compositions, methods of making and uses related thereto
US8043603B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
US8043602B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
FR2839407B1 (fr) * 2002-05-02 2004-12-17 Canon Kk Procede et dispositif d'ajustement de la taille maximale des sequences d'information transmises dans un reseau de telecommunications
EP2258401B1 (en) 2002-05-06 2014-07-09 Endocyte, Inc. Folate-receptor targeted imaging agents
KR100440725B1 (ko) * 2002-06-20 2004-07-15 주식회사 그린진 바이오텍 비생물성 스트레스에 대한 단자엽 식물의 내성을증가시키는 방법
KR20040080778A (ko) 2003-03-13 2004-09-20 삼성전자주식회사 4색 구동 액정 표시 장치 및 이에 사용하는 표시판
US7232805B2 (en) 2003-09-10 2007-06-19 Inflabloc Pharmaceuticals, Inc. Cobalamin conjugates for anti-tumor therapy
US20060024241A1 (en) * 2004-08-02 2006-02-02 Bebaas, Inc. Vitamin B12 compositions
BRPI0610419A2 (pt) * 2005-05-17 2012-10-23 Cargill Inc lecitina granular, lisolecitina, processo para produzir lecitina granular, composição granular, processo para produzir uma composição de lecitina granular, produto, e, processos para produzir lisolecitina granular e para produzir uma composição de lisolecitina granular
JP5175723B2 (ja) 2005-07-05 2013-04-03 パーデュー・リサーチ・ファウンデーション 単球介在性疾患を治療するための組成物の調製
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
WO2007030108A1 (en) * 2005-09-07 2007-03-15 Bebaas, Inc. Vitamin b-12 compositions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
EP1940473A2 (en) 2005-09-23 2008-07-09 Purdue Research Foundation Multiphoton in vivo flow cytometry method and device
KR100658436B1 (ko) * 2005-12-09 2006-12-27 한국화학연구원 아데노실코발라민 함유 피부질환 치료용 외용제 조성물
US20130084329A1 (en) 2005-12-09 2013-04-04 Hanall Biopharma Co., Ltd. Compositions for external application, containing adenosylcobalamin for improvement of skin diseases
US8168164B2 (en) 2006-02-03 2012-05-01 Purdue Research Foundation Targeted conjugates and radiation
EP2087337A4 (en) 2006-11-03 2010-09-08 Purdue Research Foundation METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY
CA2677792C (en) 2007-02-07 2015-04-14 Purdue Research Foundation Positron emission tomography imaging method
WO2008109068A2 (en) * 2007-03-05 2008-09-12 Syracuse University A conjugate of insulin and vitamin b12 for oral delivery
US20110092416A1 (en) * 2007-03-05 2011-04-21 Robert Patrick Doyle Vitamine B12 - Peptide Conjugates for Oral Delivery
US7851342B2 (en) * 2007-03-30 2010-12-14 Intel Corporation In-situ formation of conductive filling material in through-silicon via
CA2688308A1 (en) 2007-05-25 2008-12-04 Purdue Research Foundation Method of imaging localized infections
CA2695366C (en) * 2007-08-03 2016-10-04 Shaklee Corporation Nutritional supplement system
US20100330161A1 (en) * 2009-06-29 2010-12-30 Syracuse University Technology Transfer And Industrial Development Office Oral delivery of tetanus toxoid
WO2011130716A2 (en) 2010-04-16 2011-10-20 Access Pharmaceuticals, Inc. A nanostructures containing vitamin b12 for facilitated delivery of drugs across biological barriers
US8614184B2 (en) 2010-09-22 2013-12-24 Ronald P. Santasiero HCG formulations for achieving weight loss
WO2012122313A2 (en) 2011-03-08 2012-09-13 Access Pharmaceuticals, Inc. Targeted nanocarrier systems for delivery of actives across biological membranes
US9120858B2 (en) 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor
US9289507B2 (en) 2012-05-17 2016-03-22 Extend Biosciences, Inc. Carriers for improved drug delivery
WO2015126841A1 (en) 2014-02-18 2015-08-27 Plasmatech Biopharmaceuticals, Inc. Nutritional and therapeutic mucoadhesive formulations
US9616109B2 (en) 2014-10-22 2017-04-11 Extend Biosciences, Inc. Insulin vitamin D conjugates
WO2016065042A1 (en) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Therapeutic vitamin d conjugates
US9789197B2 (en) 2014-10-22 2017-10-17 Extend Biosciences, Inc. RNAi vitamin D conjugates
ES2811347T3 (es) 2015-08-14 2021-03-11 Endocyte Inc Método de formación de imágenes con un compuesto quelante
AU2023353057A1 (en) 2022-09-30 2025-05-01 Extend Biosciences, Inc. Long-acting parathyroid hormone

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2372066A (en) * 1940-12-23 1945-03-20 Parke Davis & Co Biological product and process of obtaining same
US3042588A (en) * 1957-04-04 1962-07-03 Distillers Co Yeast Ltd Process for producing cobalaminpeptide complexes
GB963373A (en) * 1961-12-11 1964-07-08 Glaxo Group Ltd Improvements in or relating to substituted cobamides
GB1152461A (en) * 1965-06-16 1969-05-21 Ivan Rolovich New Derivatives of Cobalamins
FR5372M (instruction) * 1966-02-10 1967-10-16
BE774108A (fr) * 1970-10-28 1972-04-18 Boige Jean Derives de l'hydroxocobalamine, procede pour leur preparation et utilisation de ces derives en therapeutique
IT1044233B (it) * 1973-04-04 1980-03-20 Zambelletti L S P A Derivati della vitamina bi2 ad azione vitaminica di lunga durata
JPS5247012B2 (instruction) * 1974-11-16 1977-11-29
US3981863A (en) * 1975-02-25 1976-09-21 Micromedic Diagonistics, Inc. Cyanocobalamin derivatives
US4133951A (en) * 1975-05-08 1979-01-09 The Radiochemical Centre Limited Vitamin B-12 cobalt-57 and process
DE2546474A1 (de) * 1975-10-17 1977-04-21 Murray M D Israel Injizierbares pharmazeutisches thyroxinpraeparat und verfahren zu dessen herstellung
FR2373285A1 (fr) * 1976-11-25 1978-07-07 Roussel Uclaf Nouveaux derives du coenzyme b 12, procede de preparation et application a titre de medicaments de ces nouveaux produits
DE2718700A1 (de) * 1977-04-27 1978-11-02 Hans A Dipl Chem Dr Thoma Verfahren zur gesamtbestimmung von hormonen und pharmaka
US4209614A (en) * 1978-05-30 1980-06-24 E. R. Squibb & Sons, Inc. Vitamin B12 derivative suitable for radiolabeling
US4377570A (en) * 1979-01-29 1983-03-22 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
US4360358A (en) * 1980-03-07 1982-11-23 Yash Sharma Immunoassay with solid phase having coating containing blood platelet substitute
CA1165238A (en) * 1980-03-12 1984-04-10 Demetrios P. Papahadjopoulos Activated liposomes and method
ATE30780T1 (de) * 1981-06-22 1987-11-15 Battelle Memorial Institute Verfahren zum bestimmen bioaktiver substanzen.
CA1180273A (en) * 1981-06-22 1985-01-02 Technicon Instruments Corporation Assay of vitamin b in12 xx
US4454125A (en) * 1982-04-22 1984-06-12 Demopoulos Harry B Dry powder formulations having improved flow and compressibility characteristics, and method for the preparation thereof
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US4746508A (en) * 1983-06-06 1988-05-24 Beth Israel Hospital Assn. Drug administration
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US4751285A (en) * 1986-10-09 1988-06-14 Toohey John I Derivative of cobalamin containing persulfide sulfur and glutathione
IL84167A (en) * 1986-10-24 1991-04-15 Southern Res Inst Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response

Also Published As

Publication number Publication date
ATE64534T1 (de) 1991-07-15
DK292587D0 (da) 1987-06-09
IL80264A0 (en) 1987-01-30
EP0220030A2 (en) 1987-04-29
JPH08779B2 (ja) 1996-01-10
HK69094A (en) 1994-07-22
WO1987002251A1 (en) 1987-04-23
DK167099B1 (da) 1993-08-30
NZ217821A (en) 1989-07-27
ES2051690T3 (es) 1994-07-01
CN86107590A (zh) 1987-05-20
IN165029B (instruction) 1989-08-05
US5428023A (en) 1995-06-27
KR940003057B1 (ko) 1994-04-13
CN1045391C (zh) 1999-10-06
EP0220030A3 (en) 1987-09-30
US5589463A (en) 1996-12-31
DK292587A (da) 1987-06-09
ZA867703B (en) 1987-06-24
CA1330791C (en) 1994-07-19
GR3002160T3 (en) 1992-12-30
JPS63501015A (ja) 1988-04-14
KR870700361A (ko) 1987-12-28
EP0220030B1 (en) 1991-06-19

Similar Documents

Publication Publication Date Title
IL80264A (en) Complexes of vitamin b12 or its analogues,their preparation and pharmaceutical compositions containing them
GB2185397B (en) Drug delivery system
DK156375C (da) Praeparater til oral administration til droevtyggere med langvarig medikamentafgivelse
LTIP1652A (en) Protein, biologically active hormone, method for protein production, pharmaceutical preparation
PH24331A (en) Drug delivery system
DE3776946D1 (de) Nasale verabreichung von arzneimitteln.
ZA873696B (en) Pulsatile drug delivery system
IT8767796A0 (it) Forma farmaceutica di dosaggio per somministrazione orale con erogazione controllata di un ingrediente attivo
GB8712176D0 (en) Drug delivery system
ZA849802B (en) Delivery system for controlled administration of beneficial agent to ruminants
GB8616007D0 (en) Connecting medicament delivery cannula to apparatus
PT85155A (en) Process for preparing pharmaceutical compositions for parenteral administration containing proteins having fibrinolytic activity
SE7900458L (sv) Liposom-avgivningssystem for lekemedel
ZA881053B (en) Prostaglandin e1 derivatives as pharmacologically active agents,and pharmaceutical compositions containing these compounds,especially for transcutaneous administration
HUT45249A (en) Process for producing 6,7,8,9-tetrahydro-10-methylpyrido/1,2-a/indol-9-amines, theyr derivatives and pharmaceutical compositions containing them as active components
MY100780A (en) Azumolene dosage form.
HUT44770A (en) Process for producing 6-phenoxymethyl-4-hydroxy-tetrahydropyran-2-one derivatives and pharmaceutical preparations comprising them as active substance
IT8722647A0 (it) Composizione farmaceutica per somministrazione nasale.
HUT44754A (en) Process for producing gem-dihalogen- and tetrahalogen-1,12-diamino-4,9-diaza-dodecane derivatives and pharmaceutical preparations comprising such compounds
IT8520712A0 (it) Formulazioni farmaceutiche per stimolare la liberazione di ormone somatotropo.
ES2016052A6 (es) Procedimiento para preparar derivados de adenosinmonofosfonato (amp) ciclico y de guanosinmonofosfonato (gmp) ciclico.
IL84777A (en) Prevention of bovine respiratory disease complex in cattle by administration of interferon
FR2224147A1 (en) Uridine-5'-monophosphate contg. compsns - used to accelerate glucuronide formation
GB8723744D0 (en) Topical drug administration systems
ZA879325B (en) Prevention of bovine respiratory disease complex in cattle by administration of interferon

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees