IL80215A0 - 5,6,7,8-tetrahydro-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
5,6,7,8-tetrahydro-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL80215A0 IL80215A0 IL80215A IL8021586A IL80215A0 IL 80215 A0 IL80215 A0 IL 80215A0 IL 80215 A IL80215 A IL 80215A IL 8021586 A IL8021586 A IL 8021586A IL 80215 A0 IL80215 A0 IL 80215A0
- Authority
- IL
- Israel
- Prior art keywords
- lower alkyl
- tetrahydro
- beta
- processes
- preparation
- Prior art date
Links
- XLUKCVDNZMRJNM-UHFFFAOYSA-N 6,7,8,9-tetrahydro-5h-pyrido[3,4-b]indole Chemical class N1C2=CN=CC=C2C2=C1CCCC2 XLUKCVDNZMRJNM-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 phenyloxy Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Photoreceptors In Electrophotography (AREA)
- Eyeglasses (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853535928 DE3535928A1 (de) | 1985-10-04 | 1985-10-04 | Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL80215A0 true IL80215A0 (en) | 1987-01-30 |
Family
ID=6283083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80215A IL80215A0 (en) | 1985-10-04 | 1986-10-02 | 5,6,7,8-tetrahydro-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4855295A (da) |
| EP (1) | EP0217737B1 (da) |
| JP (1) | JPH0759580B2 (da) |
| AT (1) | ATE66226T1 (da) |
| AU (1) | AU593024B2 (da) |
| CA (1) | CA1269981A (da) |
| DE (2) | DE3535928A1 (da) |
| DK (1) | DK169581B1 (da) |
| ES (1) | ES2039360T3 (da) |
| FI (1) | FI864018A7 (da) |
| GR (1) | GR3002944T3 (da) |
| HU (1) | HU195814B (da) |
| IE (1) | IE58896B1 (da) |
| IL (1) | IL80215A0 (da) |
| NO (1) | NO164354C (da) |
| ZA (1) | ZA867616B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0738717A1 (en) * | 1990-10-09 | 1996-10-23 | Neurogen Corporation | Certain substituted pyrimidines as intermediates for production of cycloalkyl and azacycloalkyl pyrrolopyrimidines |
| FR2677024B1 (fr) * | 1991-05-29 | 1995-03-03 | Centre Nat Rech Scient | Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant. |
| US5367077A (en) * | 1992-04-08 | 1994-11-22 | Neurogen Corporation | Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands |
| AU664912B2 (en) * | 1992-09-02 | 1995-12-07 | Dainippon Pharmaceutical Co. Ltd. | Novel 3-oxadiazolyl-1,6-naphthyridine derivatives |
| DE4308788A1 (de) * | 1993-03-18 | 1994-09-22 | Bayer Ag | Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate |
| CA2140722A1 (en) * | 1994-01-24 | 1995-07-25 | Joseph A. Jakubowski | Beta-carboline thromboxane synthase inhibitors |
| US5550118A (en) * | 1994-01-31 | 1996-08-27 | Eli Lilly And Company | Polyhydronorharman synthase inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES273769A1 (es) * | 1961-01-18 | 1962-06-01 | Geigy Ag J R | Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico |
| NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
| DE3240511A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von ss-carbolinderivaten |
| DE3240513A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung |
| DK149270C (da) * | 1983-05-27 | 1986-08-25 | Schering Ag | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
| DK240084D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | New beta-carboline-3-oxadiazolyl derivatives |
-
1985
- 1985-10-04 DE DE19853535928 patent/DE3535928A1/de not_active Withdrawn
-
1986
- 1986-10-02 DK DK471686A patent/DK169581B1/da active
- 1986-10-02 IL IL80215A patent/IL80215A0/xx not_active IP Right Cessation
- 1986-10-03 AT AT86730154T patent/ATE66226T1/de not_active IP Right Cessation
- 1986-10-03 ES ES198686730154T patent/ES2039360T3/es not_active Expired - Lifetime
- 1986-10-03 FI FI864018A patent/FI864018A7/fi not_active Application Discontinuation
- 1986-10-03 HU HU864182A patent/HU195814B/hu not_active IP Right Cessation
- 1986-10-03 DE DE8686730154T patent/DE3680850D1/de not_active Expired - Lifetime
- 1986-10-03 NO NO863962A patent/NO164354C/no unknown
- 1986-10-03 JP JP61234694A patent/JPH0759580B2/ja not_active Expired - Lifetime
- 1986-10-03 EP EP86730154A patent/EP0217737B1/de not_active Expired - Lifetime
- 1986-10-06 CA CA000519910A patent/CA1269981A/en not_active Expired - Lifetime
- 1986-10-06 IE IE262986A patent/IE58896B1/en not_active IP Right Cessation
- 1986-10-06 ZA ZA867616A patent/ZA867616B/xx unknown
- 1986-10-06 US US06/915,357 patent/US4855295A/en not_active Expired - Fee Related
- 1986-10-07 AU AU63662/86A patent/AU593024B2/en not_active Ceased
-
1991
- 1991-10-18 GR GR91401328T patent/GR3002944T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA867616B (en) | 1987-05-27 |
| JPS62181278A (ja) | 1987-08-08 |
| NO164354C (no) | 1990-09-26 |
| NO164354B (no) | 1990-06-18 |
| AU6366286A (en) | 1987-04-09 |
| JPH0759580B2 (ja) | 1995-06-28 |
| GR3002944T3 (en) | 1993-01-25 |
| FI864018A0 (fi) | 1986-10-03 |
| DK471686D0 (da) | 1986-10-02 |
| FI864018A7 (fi) | 1987-04-05 |
| NO863962D0 (no) | 1986-10-03 |
| ES2039360T3 (es) | 1993-10-01 |
| EP0217737A2 (de) | 1987-04-08 |
| US4855295A (en) | 1989-08-08 |
| AU593024B2 (en) | 1990-02-01 |
| EP0217737A3 (en) | 1988-06-01 |
| NO863962L (no) | 1987-04-06 |
| DK471686A (da) | 1987-04-05 |
| IE862629L (en) | 1987-04-04 |
| HUT42091A (en) | 1987-06-29 |
| DK169581B1 (da) | 1994-12-12 |
| DE3680850D1 (de) | 1991-09-19 |
| DE3535928A1 (de) | 1987-04-09 |
| IE58896B1 (en) | 1993-12-01 |
| EP0217737B1 (de) | 1991-08-14 |
| ATE66226T1 (de) | 1991-08-15 |
| HU195814B (en) | 1988-07-28 |
| CA1269981A (en) | 1990-06-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3262880D1 (en) | Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations | |
| ES8205398A1 (es) | Un procedimiento para la preparacion de derivados de hidan- toina | |
| NZ218243A (en) | B-carboline derivatives and pharmaceutical compositions | |
| IL80216A0 (en) | 3-vinyl-and 3-ethinyl-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| DE69004815D1 (de) | 1,8-Benzonaphthyridinderivate, ihre Herstellung und diese enthaltende Zusammensetzungen. | |
| ES466366A1 (es) | Un procedimiento para preparar derivados de metasulfonamido-benzamida. | |
| IL80215A0 (en) | 5,6,7,8-tetrahydro-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| IL72166A0 (en) | Beta-carboline derivatives and pharmaceutical compositions containing the same | |
| ZA858418B (en) | 5-alkyl-1-phenyl-2-piperazinoalkylpyrazoline-3-one compounds and methods for the preparation thereof,intermediates for use in the preparation of said compounds and medicaments containing said compounds | |
| DE3171074D1 (en) | Phenylpiperazine derivatives of heterylphenols and hetarylanilines, their preparation and their pharmaceutical compositions | |
| IL61275A (en) | 5-halo-6h-1,2,4,6-thiatriazine-1,1-dioxides,their manufacture and their use as herbicides | |
| HUT43068A (en) | Process for preparing 5-amino-alkyl-beta-carboline derivatives and pharmaceutical compositions containing them | |
| DE3374783D1 (en) | Beta-lactam antibiotics, process for their preparation and preparations containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |