IL79881A - Populations of random coding series of oligonucleotides and peptides - Google Patents

Populations of random coding series of oligonucleotides and peptides

Info

Publication number
IL79881A
IL79881A IL7988186A IL7988186A IL79881A IL 79881 A IL79881 A IL 79881A IL 7988186 A IL7988186 A IL 7988186A IL 7988186 A IL7988186 A IL 7988186A IL 79881 A IL79881 A IL 79881A
Authority
IL
Israel
Prior art keywords
population
discrete
units
peptide
antibodies
Prior art date
Application number
IL7988186A
Other languages
English (en)
Hebrew (he)
Other versions
IL79881A0 (en
Original Assignee
Pieczenik George
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pieczenik George filed Critical Pieczenik George
Publication of IL79881A0 publication Critical patent/IL79881A0/xx
Publication of IL79881A publication Critical patent/IL79881A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL7988186A 1985-08-28 1986-08-28 Populations of random coding series of oligonucleotides and peptides IL79881A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77039085A 1985-08-28 1985-08-28

Publications (2)

Publication Number Publication Date
IL79881A0 IL79881A0 (en) 1986-11-30
IL79881A true IL79881A (en) 1995-12-08

Family

ID=25088390

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7988186A IL79881A (en) 1985-08-28 1986-08-28 Populations of random coding series of oligonucleotides and peptides

Country Status (6)

Country Link
EP (1) EP0241487B1 (de)
AT (1) ATE165363T1 (de)
AU (1) AU626252B2 (de)
DE (1) DE3650676T2 (de)
IL (1) IL79881A (de)
WO (1) WO1987001374A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US7413537B2 (en) 1989-09-01 2008-08-19 Dyax Corp. Directed evolution of disulfide-bonded micro-proteins
FR2656626B1 (fr) * 1989-12-29 1994-08-12 Pasteur Institut Fragment peptidique comprenant une sequence issue de la proteine 28 kda de schistosoma mansoni et compositions vaccinantes et/ou therapeutiques comprenant ledit fragment.
US5366862A (en) * 1990-02-14 1994-11-22 Receptor Laboratories, Inc. Method for generating and screening useful peptides
US5814460A (en) * 1990-02-14 1998-09-29 Diatide, Inc. Method for generating and screening useful peptides
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
CA2105300C (en) 1991-03-01 2008-12-23 Robert C. Ladner Process for the development of binding mini-proteins
US5672472A (en) * 1991-08-23 1997-09-30 Isis Pharmaceuticals, Inc. Synthetic unrandomization of oligomer fragments
US5747253A (en) * 1991-08-23 1998-05-05 Isis Pharmaceuticals, Inc. Combinatorial oligomer immunoabsorbant screening assay for transcription factors and other biomolecule binding
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5733731A (en) * 1991-10-16 1998-03-31 Affymax Technologies N.V. Peptide library and screening method
US6448373B1 (en) 1994-01-11 2002-09-10 Isis Pharmaceuticals, Inc. Phosphate linked oligomers formed of monomeric diols and processes for preparing same
US6184389B1 (en) 1994-01-11 2001-02-06 Isis Pharmaceuticals, Inc. Combinatorial libraries having aminodiol monomer subunits
US6828427B1 (en) 1994-01-11 2004-12-07 Isis Pharmaceuticals, Inc. Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same
JP3498316B2 (ja) * 1997-12-15 2004-02-16 藤沢薬品工業株式会社 ディジィタルハイブリダイゼーションスクリーニング
US6248541B1 (en) 2000-04-21 2001-06-19 Genencor International, Inc. Screening under nutrient limited conditions
US6534292B1 (en) 2000-05-08 2003-03-18 Genencor International, Inc. Methods for forming recombined nucleic acids
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD143794A1 (de) * 1979-06-01 1980-09-10 Liebscher Dirck Hartmut Verfahren zur isolierung langer doppelstrang-cdns-molekuele aus einer heterogenen population
JPS57129691A (en) * 1980-09-22 1982-08-11 Yunibaashiteii Obu Sazan Karif Rearranged dna active in nuclear cell and preparation thereof
GB2145092B (en) * 1983-01-28 1988-04-07 Univ New York Protective peptide antigen
US4503142A (en) * 1982-06-25 1985-03-05 Litton Bionetics, Inc. Open reading frame vectors
DE3300632A1 (de) * 1982-12-13 1984-07-12 Christian Dipl.-Ing. 8900 Augsburg Strobel Verfahren genetischer analyse und synthese
AU576750B2 (en) * 1983-03-08 1988-09-08 Chiron Mimotopes Pty Ltd Method of determining antigenically active amino acid sequences
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
DE3461093D1 (en) * 1983-07-21 1986-12-04 Scripps Clinic Res Synthetic polypeptides corresponding to portions of proteinoids translated from brain-specific mrnas, receptors, methods and diagnostics using the same
DE3328832A1 (de) * 1983-08-10 1985-02-28 Boehringer Ingelheim Diagnostika GmbH, 8046 Garching Reagenz und verfahren zur quantitativen bestimmung von antikoerpern
CA1219232A (en) * 1983-08-17 1987-03-17 Richard A. Lerner Polypeptide-induced monoclonal receptors to protein ligands
DE3586360T2 (de) * 1984-02-10 1993-01-07 Cytoclonal Pharmaceutics Inc Isolierung eines interferongens und expression desselben.
GB8404378D0 (en) * 1984-02-20 1984-03-28 Biogen Nv Dna sequence recombinant dna molecules
US4636463A (en) * 1984-04-05 1987-01-13 Scripps Clinic And Research Foundation Antibodies to human interleukin-2 induced by synthetic polypeptides
JPH07119760B2 (ja) * 1984-07-24 1995-12-20 コモンウエルス・セ−ラム・ラボラトリ−ズ・コミッション ミモトープを検出または決定する方法

Also Published As

Publication number Publication date
WO1987001374A2 (en) 1987-03-12
EP0241487A1 (de) 1987-10-21
DE3650676T2 (de) 1998-09-17
WO1987001374A3 (en) 1987-05-21
DE3650676D1 (de) 1998-05-28
IL79881A0 (en) 1986-11-30
AU6338086A (en) 1987-03-24
AU626252B2 (en) 1992-07-30
ATE165363T1 (de) 1998-05-15
EP0241487B1 (de) 1998-04-22

Similar Documents

Publication Publication Date Title
IL79881A (en) Populations of random coding series of oligonucleotides and peptides
US5866363A (en) Method and means for sorting and identifying biological information
JP5607357B2 (ja) 抗原特異的b細胞のクローン集団を獲得するための培養方法
Velazquez et al. Is the major Drosophila heat shock protein present in cells that have not been heat shocked?
US6569641B1 (en) Process for obtaining DNA, RNA, peptides, polypeptides, or protein by recombinant DNA technique
Burton Phage display
US5541291A (en) Methods and compositions useful in the diagnosis and treatment of autoimmune diseases
US5763192A (en) Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
JP3135126B2 (ja) 疾患の臨床的発現に基づく、診断用試薬を得る方法、アッセイ、及び治療剤
Bosma et al. Congenic mouse strains: the expression of a hidden immunoglobulin allotype in a congenic partner strain of BALB/c mice
CA2006334A1 (en) Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques
WO1988000974A3 (en) Genes encoding antigens of m. leprae
JPH0242977A (ja) 主要ヒトライノウイルス受容体を表現するトランスフエクション性細胞系
Borrebaeck In vitro immunization for production of murine and human monoclonal antibodies: present status
RU99101121A (ru) Полипептиды, способные к образованию антигенсвязывающих структур со специфичностью к резус-d-антигенам, днк, кодирующая их, способы их получения и применение
KR20020007281A (ko) 조류종에 있어서 폴리뉴클레오타이드 백신접종을 이용한항체의 생산방법
Parham et al. Characterization, evolution, and molecular basis of a polymorphic antigenic determinant shared by HLA-A and B products
US5891438A (en) Method for stimulating production of variable region gene family restricted antibodies through B-cell superantigen vaccination
Sioud et al. Selection of ligands for polyclonal antibodies from random peptide libraries: potential identification of (auto) antigens that may trigger B and T cell responses in autoimmune diseases
Atsushi et al. Antibodies raised against peptide fragments of bovine αs1-casein cross-react with the intact protein only when the peptides contain both B and T cell determinants
US5254459A (en) Nucleotide and amino acid sequences of protein MTP40 of M. tuberculosis and synthetic peptides derived therefrom
Shimizu et al. Japanese wild mouse, Mus musculus molossinus, has duplicated immunoglobulin γ 2a genes
US5171839A (en) Nucleotide and amino acid sequences of protein mtp40 of m. tuberculosis and synthetic peptides derived therefrom
Hausman et al. Alteration of immunoglobulin phenotype in cell culture-adapted lines of two mouse plasmacytomas.
Jack et al. Immunoaffinity chromatography of clinical products

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void